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Musculoskeletal Diseases Clinical Trials

A listing of Musculoskeletal Diseases medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 134 clinical trials

Prospective SPINE Registry

This study is a prospective, multi-center, open label registry designed to collect real-world data on performance and safety data on RTI's spine products.

18 years of age All Phase N/A
A Alessandro Di Martino, MD

Comparing Reports Recorded by the Patients at the Time at Which They Feels Pain to What Patients Report at Monthly Visits to Assess Symptoms of Musculoskeletal Diseases.

Patients will be introduced to the use of a mobile application for their smartphone to record the Ecological Momentary Assessment (EMA). This app will ask the patients to assess their pain and function two times daily for 2 months. After 1 month and at the end of the 2 months, …

18 years of age All Phase N/A

Thumb Ossification Composite Index (TOCI) to Predict Skeletal Maturity and Curve Progression in AIS

Accurate skeletal maturity assessment is important for prediction of curve progression and clinical management of adolescent idiopathic scoliosis (AIS) including bracing decision and counseling for prognosis. Determination of the timing of peak growth height velocity and growth remaining are paramount important.1,2 Commonly used clinical or radiological methods are still inadequate …

years of age All Phase N/A
F For more information at the NIH Clinical Center contact Office of Patient Recruitment (OPR)

Natural History of Rheumatic Diseases in Minority Communities

This study will explore the causes of rheumatic diseases and why many of them affect certain minority communities more severely. Rheumatic diseases may cause joint pain, stiffness or swelling. Some can involve bones, muscles, tendons or ligaments. Some cause abnormalities of the immune system the body s defense against disease. …

18 - 100 years of age All Phase N/A
M M Maas, Prof. MD. PhD

Clinical Validation of BoneMRI in the Spine

BoneMRI is a quantitative 3D MRI technique that has been developed recently by MRIGuidance BV©, which is based on a multiple gradient-echo sequence and a machine learning processing pipeline. The BoneMRI technology is capable of generating CT-like, quantitative radiodensity bone MRI images to visualize cortical and trabecular bone, allowing to …

12 years of age All Phase N/A
W Won Jung Ha, Ph.D

Safety and Efficacy of Integrative Korean Medicine Treatment for Elderly After Traffic Accident

The purpose of this study was to analyze the medical records of elderly traffic accident patients hospitalized at 4 branches of Jaseng Korean Medicine Hospital to determine the status of elderly patients and the effectiveness and safety of Korean medicine combination treatment.

65 years of age All Phase N/A
F For more information at the NIH Clinical Center contact Office of Patient Recruitment (OPR)

Study of Inherited Neurological Disorders

This study is designed to learn more about the natural history of inherited neurological disorders and the role of heredity in their development. It will examine the genetics, symptoms, disease progression, treatment, and psychological and behavioral impact of diseases in the following categories: hereditary peripheral neuropathies; hereditary myopathies; muscular dystrophies; …

2 - 120 years of age All Phase N/A

Autoimmune and Autoinflammatory Genetics Study

This is an exploratory natural history protocol that will enroll patients with known genetic diseases, such as VEXAS syndrome, or as yet undiagnosed disorders of inflammation with the goal of improving our understanding of disease processes. Blood, saliva, hair, nail, or buccal samples may be collected for genetic analysis, blood …

1 years of age All Phase N/A
B Brian Leaker

OSTEOMICS: Identifying Regulators of Bone Homeostasis

Diseases of bone associated with ageing, including osteoporosis (OP) and osteoarthritis (OA), reduce bone mass, bone strength and joint integrity. Current non-surgical approaches are limited to pharmaceutical agents that are not disease modifying and have poor patient tolerability due to side effect profiles. Developing a fundamental understanding of cellular bone …

18 - 110 years of age All Phase N/A
R Richard Field, PhD FRCS

The Medacta International SMS Post-Marketing Surveillance Study

This is a Post-Marketing Surveillance of SMS femoral stem prosthesis.

18 - 75 years of age All Phase N/A

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