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Musculoskeletal Diseases Clinical Trials

A listing of Musculoskeletal Diseases medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 133 clinical trials

A Phase 1 Study of Anitocabtagene Autoleucel for the Treatment of Subjects With Non-oncology Plasma Cell-related Diseases

A Phase 1 dose-escalation study designed to evaluate the safety, tolerability, and preliminary efficacy of anito-cel in subjects with generalized myasthenia gravis (GMG). Anitocabtagene autoleucel (anito-cel) is a BCMA-directed CAR-T cell therapy.

18 years of age All Phase 1
H Hussein Alawieh

Non-invasive BCI-controlled Assistive Devices

Injuries affecting the central nervous system may disrupt the cortical pathways to muscles causing loss of motor control. Nevertheless, the brain still exhibits sensorimotor rhythms (SMRs) during movement intents or motor imagery (MI), which is the mental rehearsal of the kinesthetics of a movement without actually performing it. Brain-computer interfaces …

18 - 80 years of age All Phase N/A

Akkermansia Muciniphilia and Metabolic Side Effects of ADT

The overriding objectives of this study are: Primary outcomes: To confirm that administration of oral acetate increases the proportion of A. muciniphilia in the stool samples of patients with metastatic, castration-sensitive prostate cancer compared to a standard of care arm. To confirm tolerability and assess for side effects of oral …

18 years of age Male Phase N/A
P Philippe DOUEK, MD

Comparison of Imaging Quality Between Spectral Photon Counting Computed Tomography (SPCCT) and Dual Energy Computed Tomography (DECT)

This pilot study wants to determine to which extent SPCCT allows obtaining images with improved quality and diagnostic confidence when compared to standard Dual Energy CT (DECT), both with and without contrast agent injection. Depending on the anatomical structures/organs to be visualized during CT examinations, different scanning protocols are performed …

18 years of age All Phase N/A
D Donna Belette

Clinical Trial Assessing Human Placental Membrane Products and Standard of Care Versus Standard of Care in Nonhealing DFUs and VLUs

The purpose of the study is to evaluate the efficacy of multiple human placental membrane products and Standard of Care (SOC) versus SOC alone in the management of nonhealing diabetic foot ulcers (DFUs) and venous leg ulcers (VLUs) over 12 weeks using a modified platform trial design.

18 years of age All Phase N/A
B Bernhard Krämer, Prof. Dr.

Ergonomic Benefits From Robotically Assisted Laparoscopy for Hysterectomies and Other Indications

This is a prospective, single-center, observational clinical trial at the Department of Women's Health of the University Hospital Tübingen.

18 - 68 years of age All Phase N/A
M Martin Pelitz, Dr.

Changes in Workability and Employment Following the Work-related Medical Rehabilitation PV RehaJET

The objective of this observational study is to gain insight into a new approach to rehabilitation in Austria, with a particular focus on work-specific exercises that are dependent on the specific work-related needs of the patients. Two groups are being observed: one was referred to a three-week work-specific rehabilitation programme …

years of age All Phase N/A
P Philippe Mahaudens, PhD

Improve the Quality of Care in Patients With Orthopaedic Disorders

The main objective of the investigators is to improve the quality of care in patients with orthopedic disorders followed in St Luc hospital (Brussels Belgium). To do this, the investigators want to assess the impact of Orthopedic treatments at the structural level (bone structure, muscle, etc.), at the functional level …

1 - 90 years of age All Phase N/A
M Morten Lind, MD

The Duration of Spinal Anaesthesia - a Prospective, Observational Cohort Study

Today, surgery in an ambulatory setting is preferred for many reasons. Total hip and knee arthroplasty (THA and TKA) are now procedures where patients can be sent home on the same day of the surgical procedure. However, this requires substantial knowledge of factors affecting the length of hospital stay. In …

18 - 100 years of age All Phase N/A
J Jonathan Hill, Prof

The National Musculoskeletal Audit and Research Database

Developing and testing a musculoskeletal national audit in community/primary care

18 years of age All Phase N/A

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