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Botox Clinical Trials

A listing of Botox medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 27 clinical trials
A Avraam Ploumis

Low or High Botox Dilution for the Hemiplegic Gait?

There is debate regarding the efficiency of different dilutions of Botulin toxin type A (BTX-A) injections. Some authors believe that highly diluted BTX-A injections achieve greater neuromuscular blockade resulting in higher spasticity reduction. On the other hand, other researchers suggest that there is no difference in spasticity decrease if either …

18 years of age All Phase 1
M Mohamed E Abdel Fattah, MD

Sphenopalatine Block Versus BOTOX in Management of Chronic Migraine

This trial compares the efficacy and safety of sphenopalatine ganglion block (SPGB) and intramuscular BOTOX injection in chronic migraine.

18 - 65 years of age All Phase N/A
W William C Bennett, MD

Preoperative BOTOX® Injection for Large Ventral Hernia Repair

This study is for adults who need open surgery to repair a very large abdominal (ventral) hernia. This study tests whether a one-time, image-guided injection of a medicine commonly known as "BOTOX®" (onabotulinumtoxinA) into the side abdominal muscles 3-7 weeks before surgery helps surgeons close the abdominal wall fully at …

18 years of age All Phase 4
C Charity Ruhl, LPN

The Impact of Botox on Neuroimmune Interactions in Atopic Dermatitis

The purpose of this study is to understand cellular and molecular interactions in the skin of participants with mild-to-moderate AD, and how botulinum toxin alters these interactions.

18 years of age All Phase 1
A Ahmed A Bessar, MD, PhD

Efficacy of Nerve Block Versus Botox in Chronic Migraine Management

The goal of this clinical trial is to determine whether nerve block injections (specifically, supratrochlear and greater occipital nerve injections) are as effective as Botulinum toxin A (Botox) injections in treating chronic migraine in adults. The main questions it aims to answer are: Do nerve block injections reduce the number …

18 - 65 years of age All Phase N/A
M Mohammed S ElSharkawy, MD

Intraarticular Injection of Botox and Hyaluronic Acid in Knee Osteoarthritis

This study aims to compare the efficacy of intra-articular injection of Botulinum toxin and hyaluronic acid on pain in knee osteoarthritis.

50 years of age All Phase N/A
A Andrew Conner, MD

Effectiveness of Methods for Pyloric Drainage in esophagecTomY: Botox vs. Pyloromyotomy

The goal of this pragmatic, registry-based, randomized clinical trial is to find out if using botulinum toxin (Botox) to help drain the stomach during an esophagectomy works as well as a pyloromyotomy in patients undergoing elective esophagectomy for benign or malignant esophageal disease. Both methods are intended to prevent problems …

18 years of age All Phase 2/3
A Arunmozhimaran Elavarasi, MD DM

Onabotulinum Toxin A (Botox) in the Treatment of Pharyngo-esophageal Dysphagia

Dysphagia in patients with stroke, multiple sclerosis, parkinsonism or dystonia can occur due to relative hypertonia of the cricopharyngeus muscle. In the resting state, muscle is contracted and relaxes only during deglutition. Treatment of dysphagia by injecting botulinum toxin in the cricopharyngeus was described by Schneider et al. in 1994. …

14 years of age All Phase 2/3
J Jiun Chyi Hwang, MD

Evaluation the Efficacy Between Botox Injection and Combination Pharmacotherapy in Patients With Detrusor Overactivity

To investigates the effects of botulinum toxin type A bladder injection compared to combined pharmacotherapy with Mirabegron and Solifenacin.

20 - 90 years of age Female Phase 4
A Afra Avar, DDS

EMG-Based Evaluation of Occlusal Splint and Masseter Botox Effects on Head and Neck Muscles

This randomized controlled clinical trial aims to evaluate the individual and combined effects of occlusal splint therapy and botulinum toxin type A (BTX-A) injections into the masseter muscle on the activity of head and neck muscles in patients diagnosed with myofascial pain syndrome (MPS). MPS is a common subtype of …

18 - 55 years of age All Phase 4

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