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Botox Clinical Trials

A listing of Botox medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 25 clinical trials
M Monique Vaughan, MD

Reduction in Number of Botox Injections for Urgency Urinary Incontinence

The overall objective of this study is to determine if a reduced injection site protocol (5 injection sites) using an equivalent amount of Botox provides comparable relief of Urgency Urinary Incontinence (UUI) symptoms compared to the standard injection site protocol (15-20 injection sites). Our central hypothesis is that the 5-site …

21 years of age Female Phase N/A

Evaluate the Safety and Efficacy of HG102 as Compared to Botox® in Subject With Moderate to Severe Glabellar Lines

To evaluate the efficacy and safety of HG102 for moderate to severe Glabellar Lines, non-inferiority compared to Botox® was confirmed and safety was evaluated.

19 - 65 years of age All Phase 3

Evaluation of the Efficacy and Safety of Microneedling Combined With Botulinum Toxin-A Versus Meso-Botox Injection in the Treatment of Atrophic Acne Scars: A Split-face Comparative Study

Post-acne scars are psychologically disappointing and therapeutically challenging condition. No standard treatment for atrophic acne scars. Micro-Botox, is a highly diluted BTX-A which could be injected safely intra-dermally. It targets the superficial fibers of facial muscles, sweat, and sebaceous glands inducing pores shrinkage, decreasing the sebum and excessive sweating, in …

18 - 50 years of age All Phase N/A
E Erin Kelly, MD FRCSC

Antibiotic Prophylaxis for Bladder Botox

Injection of Botox into the bladder is a common treatment for overactive bladder. Postoperative bladder infection is one of the more frequently reported complications of this procedure. Prophylactic antibiotics given at the time of bladder Botox for the reduction of postoperative bladder infection have not been well studied. The main …

18 years of age Female Phase 4
J Jordan Gisseman, MD

Bladder Botox UTI Antibiotic Prophylaxis

Overactive bladder (OAB) is a common condition with a prevalence of 17% in the general population that significantly affects quality of life. Intradetrusor onabotulinumtoxinA injections are an advanced therapy for OAB as well as interstitial cystitis/bladder pain syndrome (IC/BPS). The most common adverse event following intradetrusor injection of onabotulinumtoxinA in …

18 years of age All Phase 4
E Elena M Cortizas, MS

Botox for Chronic Pelvic Pain

The purpose of this research study is to find out if precise, targeted injection of botulinum neurotoxin (commonly known as Botox) provides better relief of pelvic floor hypertonicity and pain than the standard method being used. The researchers want to better understand the effects (good and bad) of targeted botulinum …

18 - 75 years of age Female Phase 1
A Amanda Goslawski, MD

BoTox Into the Sternocleidomastoid Muscles (SCM)

Botulinum toxin injections have been used both in the face and neck for many years. However, injection into the sternocleidomastoid muscle (SCM) has only been done to treat neck spasms. In this study botulinum toxin will be injected into the SCM to determine if this will result in a temporary …

18 - 65 years of age All Phase 4
J Joseph LaBossiere, MD FRCSC

Antibiotic Prophylaxis for Neurogenic Bladder Botox

Injection of Botox into the bladder is a procedure used to treat neurogenic overactive bladder at the Dianne and Irving Kipnes Urology Centre in the Kaye Edmonton Clinic. A common complication following bladder Botox is bladder infection. There are no well-studied preventative antibiotics given at the time of bladder Botox …

18 - 100 years of age All Phase 2
S Shannon Y Kelly, BS

BOTOX® vs. XEOMIN® for Chronic Migraine

Chronic migraine (CM) is a disabling disorder that sidelines active duty personnel and diminishes their quality of life. It affects 1.3% to 2.4% of the general population. These numbers increase in active duty personnel, especially those returning from deployment, as well as in veterans. Furthermore, these numbers are 4-5 times …

18 - 89 years of age All Phase 3
A Avraam Ploumis

Low or High Botox Dilution for the Hemiplegic Gait?

There is debate regarding the efficiency of different dilutions of Botulin toxin type A (BTX-A) injections. Some authors believe that highly diluted BTX-A injections achieve greater neuromuscular blockade resulting in higher spasticity reduction. On the other hand, other researchers suggest that there is no difference in spasticity decrease if either …

18 years of age All Phase 1

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