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Madison, Wisconsin Clinical Trials

A listing of Madison, Wisconsin clinical trials actively recruiting patient volunteers.

Found 326 clinical trials
L Lisa Barroilhet, MD

Testing RG1-VLP Vaccine to Prevent HPV-related Cancers

This phase I trial tests the safety, side effects, and best dose of RG1-virus-like particle (VLP) in preventing human papillomavirus (HPV)-related cancers in women. RG1-VLP is a vaccine that aims to protect against rare HPV types not targeted by currently approved HPV vaccines. HPV is a common sexually-transmitted infection that …

18 - 60 years of age Female Phase 1
C Cancer Connect

IFx-Hu2.0 As An Adjunctive Therapy To Pembrolizumab In Advanced Or Metastatic Merkel Cell Carcinoma (MCC)

This Phase 1, multicenter, open-label trial will assess the safety and feasibility of IFx-Hu2.0 as adjunctive therapy to pembrolizumab in adult patients (≥18 years) with non-cutaneous Merkel Cell Carcinoma. Nine subjects will receive IFx-Hu2.0 as a visceral lesion injection in a single lesion followed by pembrolizumab.

18 years of age All Phase 1

A Study of LY4167586 in Participants With Obesity or Overweight Who Are Otherwise Healthy

The purpose of this study is to look at how safe and well-tolerated LY4167586 is in participants with obesity or overweight who are otherwise healthy. Blood tests will be performed to check how much LY4167586 gets into the bloodstream and how long it takes the body to eliminate it following …

18 - 65 years of age All Phase 1
A Anna Howery, MS

Brain Blood Vessel Responses to Changes in Blood Flow: Younger Cohort

Brain blood flow will be measured during a simulated postural change test and while breathing increased levels of carbon dioxide using magnetic resonance imaging.

20 - 40 years of age All Phase 2

Sparsentan in Posttransplant Immunoglobulin A Nephropathy or Focal Segmental Glomerulosclerosis

To evaluate the safety and efficacy of sparsentan tablets for the treatment of patients with proteinuria after kidney transplantation with once-daily dosing for 36 weeks.

18 years of age All Phase 4

Full Plate Living Nutrition Education Program

The purpose of the research is to evaluate the acceptability and feasibility of implementing a 8-session nutritional education program in a general internal medicine clinic. This program emphasizes a fiber-rich, whole foods diet consisting of fruits, vegetables, legumes, whole grains, nuts and seeds. Such interventions can improve diabetes management and …

22 - 65 years of age All Phase N/A
C Cancer Connect

OAR-Based, Dose Escalated SBRT With Real Time Adaptive MRI Guidance for Liver Metastases

The purpose of this trial is to identify a safe maximum tolerated dose level for MRI-guided Stereotactic Body Radiation Therapy (SBRT) treatment of bowel and liver metastases, respectively. Eligible participants will be on study for up to 12 months.

18 years of age All Phase N/A

Cognitive Impact of Neoadjuvant Chemotherapy for Ovarian Cancer

The purpose of this research is to assess several components of cognition in patients recently diagnosed with advanced epithelial ovarian cancer and who will be undergoing neoadjuvant chemotherapy for treatment of the cancer. 18 participants will be enrolled and can expect to be on study for approximately 10 months.

18 years of age Female Phase N/A
J Jack Jiang, MD

Aerodynamic Measurements in the Pediatric Population

The goal of this clinical trial is to create a vocal health database of people aged 4-17 with no diagnosed voice pathology. The main question it aims to answer is: what is the best way to assess pediatric voices; and, what are the differences between healthy and dysphonic pediatric voices? …

4 - 17 years of age All Phase N/A
S Shari Barlow

ORCHARDS-AIR Study

The purpose of this observational study is to compare the effectiveness of air surveillance and to better understand the relationship between household transmission and viruses detected in the air. Participants will provide nasal swabs and have an air sample surveillance device installed in their home.

4 years of age All Phase N/A

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