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Madison, Wisconsin Clinical Trials

A listing of Madison, Wisconsin clinical trials actively recruiting patient volunteers.

Found 290 clinical trials
E Erin Clements

Study of Pembrolizumab, Carboplatin, Paclitaxel, and Radiation for the Treatment of Early-Stage Anal Cancer

A single arm phase II study of pembrolizumab, carboplatin, paclitaxel, and radiation for the treatment of early-stage anal cancer. There are 2 treatments phases and then surveillance. The first treatment phase is the chemoradiation phase (Cycle 1-6, weekly cycles) which is followed by the maintenance phase (Cycle 7-14, 6 week …

18 years of age All Phase 2
E Evan Abramov

Pulmonary Artery DenerVation Clinical Study Using the Gradient Denervation System in Heart Failure Patients With Pulmonary Hypertension Group 2 (PreVail-PH2 Study)

This early feasibility study is intended to characterize the impact of pulmonary artery denervation on the quality of life in Heart Failure Patients with Group 2 Pulmonary Hypertension

22 - 85 years of age All Phase N/A
S Sara Heyn, JD, PhD

Sleep and Emotion Processing in Adolescent Post-traumatic Stress Disorder

The goal of this clinical trial is to characterize the role of sleep, emotion processing, and daily affect in post-traumatic stress disorder (PTSD) and whether improving sleep quality using slow wave activity enhancement will impact next-day affect in youth. Participants will attend 4 study visits: A clinical and trauma assessment …

15 - 18 years of age All Phase N/A

Non-invasive Stimulation of the Glymphatic System for Slowing Cognitive Decline

The purpose of this research is to demonstrate that mild stimulation of a nerve (trigeminal nerve) in the head can modulate blood flow in the brain. The modulated blood flow will restore the flow of cerebrospinal fluid (CSF) and this in turn can help improve waste clearance in the brain …

20 - 85 years of age All Phase N/A
C Cancer Connect

Real-Time MRI-Guided 3-Fraction Accelerated Partial Breast Irradiation in Early Breast Cancer

This trial will investigate a novel 3-fraction radiation regimen for participants undergoing breast-conserving therapy (BCT) for early breast cancer that will: 1) significantly reduce the duration of treatment and can be completed in one-week (5 working days) and 2) MRI-guided radiotherapy (MRIdian) would limit the volume of normal tissue radiated …

40 years of age Female Phase 2
S Stephanie Wilbrand, PhD

The AHA Oneida Study

The purpose of this clinical trial is to learn whether a cultural nutritional program can change stroke risk factors, cognitive decline, and learn how school education programs about nutrition can improve health in the Oneida Nation. Participants will undergo: A carotid ultrasound Cognitive testing Health assessment Blood work Health wellness …

7 - 85 years of age All Phase N/A
C Cancer Connect

HEARTS Trial for Thoracic Cancers

The goal of this clinical trial is to compare a new way of using magnetic resonance-guided adaptive radiation therapy (MRgART) to the standard of care linear accelerator (LINAC) radiation treatment in people with cancer in the thoracic region near the heart. The main question it aims to answer is whether …

18 years of age All Phase 2
M Maggie Chilsen

Calls and Coordination for Transitions of Care at Re-entry

The goal of this clinical trial is to learn if a short program for people being released from prison can help connect them to medical care. The main question it aims to answer is: Will there be more non-emergency, outpatient clinic visits? Researchers will compare the number of clinic visits …

18 years of age All Phase N/A
A Armin Edalatpour, MD

Effect of TXA on Reducing Bruising After Filler Injection

The goal of this clinical trial is to look at the effect tranexamic acid (TXA) may have on reducing bruising, swelling, and pain after facial filler injection. The main question it aims to answer is: Does the addition of TXA to hyaluronic acid (HA) reduce bruising, swelling, and tenderness after …

18 - 89 years of age All Phase 2
S Sascha Alexander Tuchman, MD, MHS

Selinexor and Backbone Treatments of Multiple Myeloma Patients

This study will independently assess the efficacy and safety of 11 combination therapies in 12 arms, in dose-escalation/-evaluation and expansion phases, for the treatment of patients with relapsed/refractory multiple myeloma (RRMM) and newly diagnosed multiple myeloma (NDMM). The combinations to be evaluated are: Arm 1: Selinexor + dexamethasone + pomalidomide …

18 years of age All Phase 1/2

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