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Orlando, Florida Clinical Trials

A listing of Orlando, Florida clinical trials actively recruiting patient volunteers.

Found 285 clinical trials
A Amy Chesire

A Phase 2 Study of NEU-411 in Companion Diagnostic-Positive Participants With Early Parkinson's Disease

The goal of this Phase 2 clinical trial is to investigate the efficacy and safety of NEU-411 in men and women aged 40-80 years with early Parkinson's Disease (PD) who have predicted elevations in the activity of the "leucine-rich repeat kinase 2" ("LRRK2" for short) pathway based on their genetic …

40 - 80 years of age All Phase 2

Safety, Tolerability and Efficacy Study of ARCT-032 in People With Cystic Fibrosis

ARCT-032-02 is a Phase 2, open-label, multicenter, multiple-ascending dose study of ARCT-032 in adults with CF who are not eligible for CFTR modulator therapy or are not taking CFTR modulators due to drug intolerance, poor response, or lack of access to modulators.

18 years of age All Phase 2

Safety and Effectiveness of Endoscopic Intestinal Re-Cellularization Therapy in Individuals With Type II Diabetes

This study is designed to evaluate the safety and effectiveness of endoscopic intestinal re-cellularization therapy in individuals with type 2 diabetes (T2D) inadequately controlled on non-insulin glucose-lowering medications.

22 - 70 years of age All Phase N/A

Safety, Tolerability and Pharmacokinetics of AZD1613 in Adults With Autosomal Dominant Polycystic Kidney Disease

A study to investigate safety, tolerability, and pharmacokinetics of AZD1613 following subcutaneous or intravenous administration in participants with autosomal dominant polycystic kidney disease (ADPKD).

18 - 65 years of age All Phase 1

A Study of Retatrutide (LY3437943) in Participants With Obesity or Overweight

The purpose of this study is to evaluate the efficacy and safety of retatrutide compared with placebo for body weight reduction. Participation in the study will last about 65 weeks and may include about 18 visits.

18 years of age All Phase 3

Beeline: A Phase 3 Study in GRIN-related Neurodevelopmental Disorder

The Phase 3 portion of Study RAD-GRIN-101 is a multinational, multicenter, randomized, double-blind, placebo-controlled trial followed by an open-label extension to evaluate the efficacy and safety of radiprodil in participants with GRIN-related neurodevelopmental disorder (GRIN-NDD) with a gain-of-function (GoF) genetic variant. This study will enroll two cohorts: one cohort of …

1 - 18 years of age All Phase 3
A Amoy Fraser, PhD, CCRP, PMP

De-identified Human Tissue Project

Research scientists of the University of Central Florida College of Medicine (COM) and Burnett School of Biomedical Sciences (BSBS) conduct laboratory studies in biomedical and translational medical research for the purpose of understanding human disease and developing innovative methods for diagnosing, measuring, or treating disease or disease symptoms. The key …

18 years of age All Phase N/A
A Amoy Fraser, PhD, CCRP, PMP

Blood Collection for COM/BSBS

The objective of this biospecimen collection protocol is the acquisition of blood from adult volunteers. These biospecimens will be transferred to the College of Medicine (COM)/Burnett School of Biomedical Sciences (BSBS) research scientists and their research teams for testing according to their separate IRB-approved/exempted protocols. These separate IRBapproved protocols cannot …

18 years of age All Phase N/A
R Recruitment Department

ImpaCt Of Shiftwork on METabolic Flexibility and Skeletal Muscle Clocks

The purpose of this study is to determine the impact of real-world shiftwork on metabolic flexibility.

21 - 45 years of age All Phase N/A
A Amoy Fraser, PhD, CCRP, PMP

UCF Deciding Brains

The purpose of this research study is to understand how people make trust-related decisions in healthy aging. Participants will be asked to complete one study session on the University of Central Florida (UCF) campus. The study session will be conducted in a private testing room and include a series of …

20 years of age All Phase N/A

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