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Orlando, Florida Clinical Trials

A listing of Orlando, Florida clinical trials actively recruiting patient volunteers.

Found 307 clinical trials
A Advent Health Oncology Research

PET Scan Study to Detect Prostate Cancer in Patients with Early PSA Recurrence

Flotufolastat F-18, sold under the brand name Posluma, is a radioactive diagnostic agent for use with positron emission tomography (PET) imaging for prostate cancer. The research is being done to study the capability of 18F-rhPSMA-7.3 (flotufolastat F-18) PET scan to detect prostate cancer when there are very low levels of …

18 years of age Male Phase 2

A Phase 2 Study of Budoprutug in Subjects With Primary Membranous Nephropathy

To evaluate the safety and tolerability of three dose regimens of budoprutug in subjects with PMN

18 - 70 years of age All Phase 2

A Phase I Study to Investigate the Effects of Renal Impairment on the Pharmacokinetics, Safety, and Tolerability of Opemalirsen (AZD2373)

This study is being conducted to investigate the PK, safety, and tolerability of opemalirsen in participants with renal impairment, compared to participants with normal renal function.

18 - 80 years of age All Phase 1

Study of BPN14770 in Participants With Severe Renal Impairment and Healthy Controls

The purpose of this study is to assess the pharmacokinetics (PK), safety, and tolerability of BPN14770 in participants with severe renal impairment and those with normal renal function.

18 - 85 years of age All Phase 1

A Study Evaluating BFB759 in Moderate to Severe Atopic Dermatitis

This is a double-blind, placebo-controlled study where subjects are participating for approximately 36 to 40 weeks. The study compares how well BFB759 works and how safe it is compared with a placebo.

18 - 75 years of age All Phase 2

A Study of Nemtabrutinib in Participants With Moderate Hepatic Impairment (MK-1026-015)

The purpose of this study is to compare the plasma pharmacokinetics (PK) of nemabrutinib (MK-1026) following a single oral dose of nemtabrutinib in participants with moderate hepatic impairment to that of healthy matched control participants and to evaluate the safety and tolerability of nemtabrutinib.

18 - 75 years of age All Phase 1

Phase 1 Study of BPN14770 in Participants With Hepatic Impairment and Healthy Controls

The primary purpose of this study is to assess the pharmacokinetics (PK) of BPN14770 after a single oral administration of BPN14770 in participants with mild, moderate, and severe liver impairment compared with control participants with normal hepatic function.

18 - 80 years of age All Phase 1
E Eric Schrimshaw, PhD

Economic Navigation and Strengthening to Research Unrestricted Services for Transgender Women (ENTRUST)

The overall hypothesis is that stabilizing transgender women financially while providing them tailored counselling will increase their odds of them linking to substance use services, PrEP services if they do not have HIV, and transgender women who are living with HIV will be more adherent to their ART treatment.

18 years of age Male Phase N/A
B Boehringer Ingelheim

A Study to Test How BI 1584862 is Taken up in the Blood of People With and Without Liver Problems

This study is open to adults between 18 and 80 years of age. People with a body mass index (BMI) between 18 and 42 kg/m2 can take part. This study includes people with mild, moderate, and severe liver problems, and people without liver problems as a matching control. The purpose …

18 - 80 years of age All Phase 1
A Alexander Prezioso, MD

Effect of Hepatic Impairment on the Pharmacokinetics of Mirdametinib

The purposes of this study are to determine: The pharmacokinetics (the amount of study drug in your blood and how long it takes the body to get rid of it) of the study drug and its metabolites (substances produced as the body breaks down the study drug) in participants with …

18 - 80 years of age All Phase 1

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