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A, Kuopio N Clinical Trials

A listing of A, Kuopio N clinical trials actively recruiting patients volunteers.

Found 11,558 clinical trials

A Phase I Study of JSKN021 in Advanced Solid Tumors

This is a Phase I, open-label, multi-center, first-in-human (FIH) clinical trial designed to evaluate the safety, tolerability, pharmacokinetic (PK) profiles, and the preliminary antitumor activity of JSKN021 in advanced malignant solid tumors.

18 - 75 years of age All Phase 1

A Study of JNJ-1761981 in Participants With Solid Tumors

The purpose of Part 1 of this study is to determine a safe, tolerable, and feasible recommended total dose of intratumorally administered JNJ-1761981. The purpose of Part 2 of this study is to identify the optimal volumetric dose of JNJ-1761981 for the treatment of tumor lesions.

18 years of age All Phase 1
H Hany F Badawy, MD

Renal SWE as a Predictor After Pediatric Pyeloplasty for UPJO

Ureteropelvic junction obstruction is an important cause of hydronephrosis and potentially reversible renal functional impairment in children. Although open pyeloplasty is an effective standard treatment, the degree of postoperative renal functional recovery varies between patients. This prospective observational cohort study will evaluate whether renal cortical shear wave elastography can predict …

6 - 18 years of age All Phase N/A
V Victoria P Werth, MD

A Study of Quinacrine in Participants With Cutaneous Lupus Erythematosus

The research study is being conducted to learn more about how patients with cutaneous lupus erythematosus (CLE) respond to the use of quinacrine. Quinacrine is a medication that was originally developed and used starting in the 1930's to treat malaria. It has been used for decades to help reduce inflammation …

18 years of age All Phase 2

A Phase 1, First-in-human Study of VX-433

The purpose of this study is to evaluate the safety, tolerability, and pharmacokinetics (PK) of VX-433 following single and multiple ascending doses, as well as to assess the effect of VX-433 on the PK of midazolam, bupropion, and hydroxybupropion.

18 - 55 years of age All Phase 1
R Rebecca Saracino, PhD

A Study of Counseling Support for Cancer Survivors Age 65+

The purpose of this study is to find out if a psychotherapy method called brief behavioral activation (BBA) can improve depression, anxiety, and overall well-being and encourage healthy lifestyle behaviors in English- and Spanish-speaking Older Adult Cancer Survivors (OACS). BBA is a therapeutic technique that guides people to set goals …

65 years of age All Phase N/A
Y Yanxia Yu

A Phase Ia Study of KMY Tablets in Healthy Subjects

This is a Phase Ia, randomized, double-blind, placebo-controlled study conducted in healthy subjects. The study plans to enroll a total of 120 participants, with both males and females included in all parts. The trial consists of three distinct parts: Part A (Single-Ascending Dose, SAD): A total of 72 subjects will …

18 - 45 years of age All Phase 1

A Study of Patients' Preferences for Primary Immune Thrombocytopenia Treatment

This study aims to evaluate treatment preferences of patients with Primary Immune Thrombocytopenia (ITP) in the United States (US) by conducting a preference elicitation survey.

18 years of age All Phase N/A

A Study of V132 in Healthy Older Participants (V132-001)

The goal of this study is to learn about the safety and immune response to the V132 vaccine in healthy older adults.

50 - 75 years of age All Phase 1
S Spencer Herard

A Study of AWT020 in Participants With Advanced Solid Tumors

This study is aimed at establishing the MTD and/or the RP2D for AWT020 monotherapy and to provide safety, tolerability, efficacy, PK, immunogenicity characteristics of AWT020.

18 years of age All Phase 1

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