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A, Kuopio N Clinical Trials

A listing of A, Kuopio N clinical trials actively recruiting patients volunteers.

Found 11,558 clinical trials

A Study to Evaluate ALN-4915 in Adult Healthy Volunteers

The purpose of this study is to evaluate the safety, tolerability, pharmacodynamics (PD) and pharmacokinetics (PK) of ALN-4915.

18 - 65 years of age All Phase 1

A Study of Brenipatide in Participants With Opioid Use Disorder

The purpose of this study is to see if brenipatide, when compared to placebo, is safe and effective for participants with opioid use disorder, when used with buprenorphine with or without naloxone. The maximum potential duration of study participation for a participant in Part A is approximately 144 weeks, maximum …

18 - 75 years of age All Phase 2

A Phase 1 Study of CLYM116 in Normal Healthy Volunteers

This Phase 1, first-in-human study will evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of CLYM116 in healthy volunteers.

18 - 60 years of age All Phase 1

A Single Ascending Dose of HRS-2162 in Healthy Subjects

The study is being conducted to evaluate the safety and tolerability of HRS-2162 injection in a single dose in healthy subjects, as well as the characteristics of PK/PD

18 - 45 years of age All Phase 1
H Huanming Wang, Ph.D

A Study of KC1036 in Adolescents With Advanced Ewing Sarcoma

This open-label, single-arm clinical trial is to evaluate the safety and effectiveness of KC1036 in treating adolescents aged 12 and above with advanced Ewing sarcoma. Participants will take KC1036 once daily, with each treatment cycle lasting 4 weeks.

12 - 18 years of age All Phase 2
C Caicun Zhou, PhD

A Study of HDM2024 in Participants With Advanced Solid Tumors

The goal of this clinical trial is to learn if the study drug can work in advanced cancer patients. The main questions it aims to answer are: Is the drug safe and tolerable ? Does the drug exhibit antitumor activity ? Participants will receive the study drug once every three …

18 - 75 years of age All Phase 1
L Leena Pandya, ND

Examining a Novel Gastrointestinal Intervention to Negate Environmental Toxicants (ENGINE)

This randomized, placebo-controlled crossover trial will test the feasibility and acceptability of using colesevelam in male firefighters with high per- and polyfluoroalkyl substances (PFAS) exposure. This trial will also explore whether colesevelam lowers blood PFAS levels and urine environmental toxicant and mold mycotoxin levels.

18 years of age Male Phase 1/2
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A Study of TAK-505 in Adults With Solid Tumors

Solid tumors occur when cells in an organ or tissue (for example in the lung or liver) start growing out of control (cancer) and form a lump or mass of cells. These solid cancers may grow very far in the general area where they started (called locally advanced) or may …

18 years of age All Phase 1/2
J Josh Oliver

Testing a Tailored Approach to Long-Term Weight Loss Success

The purpose of this study is to develop and test an adaptive, individually tailored intervention to prevent weight regain in people who have intentionally lost weight. The main questions it aims to answer are: Is an adaptive intervention with tailored re-engagement support feasible for individuals following intentional weight loss? Does …

18 - 65 years of age All Phase N/A
N Ning Li

A Study of TPD3310 in Patients With Advanced Malignant Tumors

This study is a multicenter, open phase I clinical study of dose escalation,cohort expansion study to evaluate the safety,tolerability,pharmacokinetics,pharmacodynamics, and preliminary efficacy of TPD3310 in patients withadvanced malignant solid tumors.

18 - 75 years of age All Phase 1

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