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Toronto, Canada Clinical Trials

A listing of Toronto, Canada clinical trials actively recruiting patients volunteers.

Found 1,046 clinical trials
D Drew Taylor, MSc, PhD

Cryopreserved Hair Follicles for Disease and Cell Replacement

To explore the application of cells expanded from plucked hair follicles after collection, transport, and cryopreservation, in disease modeling and cell-based therapies.

18 - 80 years of age All Phase N/A
D Dr. Venkat Bhat, M.D., F.R.C.P.C.

Digital Interventions for Adults with Treatment-Resistant Depression: a Pilot Study

The goal of this observational study is to learn about remote mental health monitoring technology for adults with treatment-resistant depression. The main question it aims to answer is: are digital mental health monitoring tools (an electronic data capture platform and wearable device (e.g., smartwatch or smart-ring)) feasible to implement alongside …

18 years of age All Phase N/A
K Kristi Downey, MSc

The Patient AS EDUcator in Anesthesia: Exploring the Patients' Experience During and After Unexpected Cesarean Delivery Under General Anesthesia to Inform Anesthetic Practice

This study aims to explore the patients' and providers' perspectives and inform future anesthetic practice for patients undergoing unexpected cesarean delivery (CD) under general anesthetic (GA). The consideration of patients' concerns, preferences, expectations, and suggestions may lead to enhanced patient satisfaction, compliance, and quality of care that future patients receive …

18 - 50 years of age Female Phase N/A
K Katarzyna Jerzak, MD

Integrated Patient Avatars for Guiding Systemic Therapy Treatments in Metastatic Breast Cancer Patients

The investigators propose to use clinically validated patient avatar technology ("PDXovo") that can test multiple drugs against patients' cancers to identify the most promising systemic therapy for each individual.

18 years of age All Phase N/A
W Wilton vanKlei, MD

Long Term Cardiovascular Disease Event Risk for Patients Undergoing Major Non-Cardiac Surgery

The goal of this observational study is to learn whether the healthy lifestyle choices made around surgery can influence an individual's long term risk of developing cardiovascular disease. Patients will be observed 1-month prior to and 3-months following surgery to assess their risk of developing cardiovascular disease.

45 - 75 years of age All Phase N/A
J Jayanta Chowdhury

MCID and PASS for Acute Pain and Quality of Recovery After Orthopedic Surgery

This study seeks to define what constitutes an MCID and a PASS in patients undergoing a variety of elective major orthopedic surgery.

18 - 80 years of age All Phase N/A
Y Yishay Szekely, MD

NIVIA-Hemodynamics

This is an investigator-initiated, single-center, single-arm prospective study to compare non-invasive hemodynamic assessment using transthoracic echocardiography (TTE) and lung ultrasound (LUS) and hemodynamic assessment using PAC. Patients who have been hemodynamically assessed using PAC will be invited to participate. Each patient will undergo TTE and LUS immediately after first invasive …

18 years of age All Phase N/A
J Jordan Rubin

Autologous Hair Follicle Derived Secretome as Adjunct to Aesthetic Procedures

Non-interventional, multi-site, prospective, open-label, observational, real-world study of autologous hair follicle secretome use.

18 - 60 years of age All Phase N/A
Z Zujaja-Tul-Noor Zujaja-Tul-Noor, MSc

Weaning is Winning? (WeWin Study)

We propose a multicenter prospective study on pediatric patients with intestinal failure (IF) who weaned off parenteral nutrition (PN).

- 18 years of age All Phase N/A
L Laurent Brochard, MD

Pressure Muscle Index and Threshold of Over-assistance During Pressure Support Ventilation

Pressure support ventilation (PSV) is used to assist the breathing of the intubated patient with some pressure from the ventilator. This support aims at avoiding excessive inspiratory effort, while ensuring a certain degree of training of the patient's inspiratory muscle. Avoiding both minimal and excessive assistance is thus important for …

18 years of age All Phase N/A

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