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Toronto, Canada Clinical Trials

A listing of Toronto, Canada clinical trials actively recruiting patients volunteers.

Found 1,037 clinical trials
S Sabine Nabecker, MD

The Patient AS EDUcator in Anesthesia: Exploring the Patients' Experience During and After Unexpected Cesarean Delivery Under General Anesthesia to Inform Anesthetic Practice

This study aims to explore the patients' and providers' perspectives and inform future anesthetic practice for patients undergoing unexpected cesarean delivery (CD) under general anesthetic (GA). The consideration of patients' concerns, preferences, expectations, and suggestions may lead to enhanced patient satisfaction, compliance, and quality of care that future patients receive …

18 - 50 years of age Female Phase N/A

Clindamycin Phosphate, Adapalene, and Benzoyl Peroxide Triple Combination Gel in Canadian Patients With Acne Vulgaris

The goal of this observational study is to learn about the effects of a treatment that contains clindamycin phosphate, adapalene, and benzoyl peroxide in people with acne. The main questions the study aims to answer are: How satisfied are people with this treatment? How well do people follow the treatment …

12 years of age All Phase N/A
D Drew Taylor, MSc, PhD

Cryopreserved Hair Follicles for Disease and Cell Replacement

To explore the application of cells expanded from plucked hair follicles after collection, transport, and cryopreservation, in disease modeling and cell-based therapies.

18 - 80 years of age All Phase N/A
J Julie Hallet, MD MSc FRCSC FSSO

Life Following Excision of Neuroendocrine Tumors

Neuroendocrine tumors (NETs), often seen as "chronic cancer" present a survival paradox with relatively prolonged patient survival despite active disease. Treatment strategies emphasize management over cure, integrating tumor control with quality of life (QOL) considerations. Surgery is a cornerstone of NET management but demands a careful balance between its potential …

18 years of age All Phase N/A
J Jessie Hulst

Weaning is Winning? (WeWin Study)

We propose a multicenter prospective study on pediatric patients with intestinal failure (IF) who weaned off parenteral nutrition (PN).

- 18 years of age All Phase N/A
H Hon S Leong, PhD

Integrated Patient Avatars for Guiding Systemic Therapy Treatments in Metastatic Breast Cancer Patients

The investigators propose to use clinically validated patient avatar technology ("PDXovo") that can test multiple drugs against patients' cancers to identify the most promising systemic therapy for each individual.

18 years of age All Phase N/A
W Wilton vanKlei, MD

Long Term Cardiovascular Disease Event Risk for Patients Undergoing Major Non-Cardiac Surgery

The goal of this observational study is to learn whether the healthy lifestyle choices made around surgery can influence an individual's long term risk of developing cardiovascular disease. Patients will be observed 1-month prior to and 3-months following surgery to assess their risk of developing cardiovascular disease.

45 - 75 years of age All Phase N/A
J Jayanta Chowdhury

MCID and PASS for Acute Pain and Quality of Recovery After Orthopedic Surgery

This study seeks to define what constitutes an MCID and a PASS in patients undergoing a variety of elective major orthopedic surgery.

18 - 80 years of age All Phase N/A
Y Yishay Szekely, MD

NIVIA-Hemodynamics

This is an investigator-initiated, single-center, single-arm prospective study to compare non-invasive hemodynamic assessment using transthoracic echocardiography (TTE) and lung ultrasound (LUS) and hemodynamic assessment using PAC. Patients who have been hemodynamically assessed using PAC will be invited to participate. Each patient will undergo TTE and LUS immediately after first invasive …

18 years of age All Phase N/A
E Edward LW Chow, MBBS

Prospective Assessment of Acute Skin Toxicities in Breast Cancer Patients Undergoing Retreatment with 40 Gy in 15 Fractions Radiation Therapy

The most common cancer affecting Canadian women is breast cancer, with an estimated 1 in 8 women expected to be diagnosed with breast cancer during their lifetime. Improved screening and treatment have decreased mortality of breast cancer patients, however 14% of cancer-related deaths in Canadian women are still due to …

18 years of age All Phase N/A

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