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a, a N Clinical Trials

A listing of a, a N clinical trials actively recruiting patients volunteers.

Found 11,315 clinical trials
M Marta Not Monegal, MSc

Effects of Application of a Motor Programme on Neurological Maduration in Children

The persistence of primitive reflexes in school-age children can affect neuromotor maturation. Some studies link the persistence of primitive reflexes with specific learning difficulties, low academic performance, neurodevelopmental disorders, and behavioral problems. There are studies that suggest introducing intervention programs to help integrate the activity of these reflexes. The objective …

7 - 9 years of age All Phase N/A

SARS-COV-2 Infection in Kidney Transplant Recipients: a Brazilian Multicenter Study

COVID-19 is the pandemic disease caused by the SARS-CoV-2 coronavirus. It is a highly contagious viral disease, the condition of which main clinical symptoms are characterized by fever and respiratory symptoms. Evidence indicates to worse outcomes in patients with pre-existing diseases, such as diabetes, arterial hypertension, heart disease, pneumopathies, chronic …

years of age All Phase N/A
S Sophie Miller

A Dose Escalation Study of AV-380 in Cancer Patients With Cachexia

This open label ascending dose study is designed to evaluate the safety, pharmacokinetics (PK), pharmacodynamics (PD), and immunogenicity of AV-380 in cancer patients with Cachexia. AV-380 is an immunoglobulin (Ig) G1 monoclonal antibody (mAb) intended to bind circulating human growth differentiation factor 15 (GDF-15), a cytokine involved in cancer-induced cachexia.

18 years of age All Phase 1
D Denise Juhr

Measurement of Bladder Pressure With a Novel External Device (Cystomanometer) - Home Use

The investigators have developed a novel pressure monitoring device that hooks to standard urinary catheters that are used by patients with a neurogenic bladder on daily clean intermittent catheterization. The device has already been demonstrated to be accurate compared to the gold standard in clinic urodynamics. This study will assess …

1 - 99 years of age All Phase N/A
Y Yongjun Wang, MD

A Clinical Trial of MT200605 for the Treatment of Acute Ischemic Stroke

MT200605 is an agonist of the receptor tyrosine kinase B (TrkB). It exerts brain-derived neurotrophic factor (BDNF)-like effects, protecting the structure and function of neural tissues in the brain. Simultaneously, it enhances ATP synthesis in the mitochondria of the striatum and bolsters antioxidant and free radical-scavenging capabilities. MT200605 is anticipated …

18 - 80 years of age All Phase 2

Prospective Longitudinal Study of Heylo™ for People Living With a Stoma

This study aims to longitudinally evaluate the usage and long-term benefits of the CE-marked device, Heylo™, a digital leakage notification system for people with intestinal stomas. The system, which includes a smartphone application, an adhesive sensor layer, and a Bluetooth transmitter, notifies users of changes in their baseplate status, potentially …

18 years of age All Phase N/A
T Tao Han, Dr.

A Prospective Study on the Treatment of cLM Based on ICG Imaging

The goal of this prospective randomized controlled study is to explore the role of indocyanine green-fluorescence imaging in management of cystic lymphatic malformation.. To clarify the application value of indocyanine green-fluorescence imaging in both diagnosis and treatment of cystic lymphatic malformation (cLM) in children, is helpful for exploring pathogenesis of …

30 - 16 years of age All Phase N/A
S Site Contact

A Study of YKST02 in Participants With Relapsed or Refractory Multiple Myeloma

This study aims to provide a basis for further clinical development of YKST02. YKST02 is a study medicine that targets multiple myeloma and activates the human body to fight against this disease.

18 - 75 years of age All Phase 1
X Xiaohong Han

A Safety and Tolerability Study of BPR-30221616 Injection in Healthy Subjects

The purpose of this study is to determine the safety, tolerability, pharmacokinetics、 pharmacodynamics and immunogenicity of BPR-30221616 in healthy subjects.

18 - 65 years of age All Phase 1
I Ina Callebaut, PhD

Using Digital Health in a Postoperative Setting After Major Surgery: Survey Study

This study aims to explore patients' use of digital services for self-management of their health following major surgery at Jessa Hospital. Besides this, the study evaluates patients' ability to process and critically assess health information during recovery, their understanding of health concepts and risk factors, and their perception of data …

18 years of age All Phase N/A

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