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a, a N Clinical Trials

A listing of a, a N clinical trials actively recruiting patients volunteers.

Found 11,315 clinical trials
L Luisa Klotz, Prof.

Effects of a Combined Supplementation of Conjugated Linoleic Acid (CLA) and Probiotics (Vivomixx®) as add-on to a First-line Immunotherapy in Relapsing-remitting Multiple Sclerosis

The goal of this randomized, double-blind, placebo-controlled multicenter study is to investigate whether the combination of food supplementation with Tonalin® and specific probiotics is a safe and effective add-on to first-line disease modifying treatment (DMT, interferon-beta derivatives as well as glatirameracetate and other glatirameroids) in relapsing remitting MS (RRMS). 100 …

18 - 60 years of age All Phase N/A
A Albert Cheng

A Study to Investigate the Safety of DSP-3077 After a Unilateral Eye Injection in Male and Female Participants 18 Years of Age or Older With Retinitis Pigmentosa

The Goal of this study is to evaluate the safety, tolerability, and clinical responses following single dose of DSP-3077. Study enrolls both male and female patients in 3 cohorts with each cohort defined by visual acuity (VA) criteria and dose level of DSP-3077. Each cohort will include 4 participants.

18 years of age All Phase 1/2

A Study to Test a New Immunotherapy, ABX-001, Alone and in Combination With the Marketed Drug, Pembrolizumab, for the Treatment of Tumors Previously Treated With Other Therapies

This is a Phase I/Ib first-in-human, open-label, non-randomized, multicenter, multi-country study to evaluate the safety and tolerability and to establish a recommended Phase 2 dose (RP2D) as well as assess preliminary clinical activity of ABX-001 administered intravenously (IV) alone (Part A) or co-administered with pembrolizumab (Part B) in participants with …

18 years of age All Phase 1
N Nancy Kuntz, MD

A Study to Assess the Safety of ARGX-124 in Healthy Volunteers

This study aims to assess the safety of ARGX-124 in healthy adults. Another aim is to measure the amount of ARGX-124 in the blood over time to learn how it acts and moves in the body and how the immune system responds to it. Participants will remain in the study …

18 - 65 years of age All Phase 1

A Phase 2/3 Study of Brepocitinib in Adults With Lichen Planopilaris

This study will evaluate the clinical safety and efficacy of oral brepocitinib in participants with lichen planopilaris

18 years of age All Phase 2/3

A Study of MB-001 in Moderately to Severely Active Ulcerative Colitis

The goal of this clinical trial is to learn if MB-001, an oral biologic, is able to treat patients with ulcerative colitis. Participants will be asked to take MB-001 or a matching placebo once-daily for a period of 12 weeks. Researchers will compare MB-001 to placebo to investigate its effects …

18 - 75 years of age All Phase 1/2
K Kara M Smith, MD MSCI FAAN

Delirium in Neurodegenerative Disease Patients: A Music Therapy Intervention for Hospital Care

In this pilot study a new kind of music therapy will be created and tested to help prevent confusion, called delirium, that can happen in the hospital. This can affect people with brain diseases like Alzheimer's disease and Parkinson's disease. Each of the anticipated 30 participants will have up to …

60 years of age All Phase N/A
C Cristina Valles, PhD

Long-term Stability of Peri-implantitis Treatments: a 3-year Clinical Evaluation

This prospective study will include patients previously enrolled in the PER-ECL-2019-05 trial who attend the Department of Periodontology (CUO) for maintenance therapy or treatment of periodontal and/or peri-implant diseases, provided they meet the inclusion criteria. Initially, 36 patients with advanced peri-implantitis were enrolled in a randomized clinical trial evaluating the …

years of age All Phase N/A
K Kim Ross

A Phase II Study Evaluating BMS-986504 in MTAP-deleted Pancreatic Cancer

To find out if the combination of BMS-986504 plus neoadjuvant/adjuvant chemotherapy and surgery (Cohort 1) or BMS-986504 plus standard of care chemotherapy (Cohorts 2 and 3) can help to control pancreatic cancer.

18 years of age All Phase 2
Z Zhijie Wang, MD, PhD

A Clinical Trial on the Efficacy and Safety of TQB6411 for Injection

To evaluate the efficacy and safety of TQB6411 for Injection in subjects with advanced lung cancer

18 - 75 years of age All Phase 1/2

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