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a, a N Clinical Trials

A listing of a, a N clinical trials actively recruiting patients volunteers.

Found 11,315 clinical trials
A Anika Clinical Research Coordinator

Extended-release Buprenorphine as a Novel Low-dose Induction Strategy

This is a clinical trial to characterize the safety and pharmacokinetics of using extended-release buprenorphine (XR-BUP) as a novel low-dose buprenorphine induction strategy. Individuals with a diagnosis of Opioid Use Disorder (OUD) (n=30) will be admitted to an inpatient unit to complete study procedures over the course of 3 days. …

18 years of age All Phase 2
E Emily M Bowers, BS

Digital Intervention for Adults With Misophonia: A Randomized Controlled Trial

The goal of this clinical trial is to test an online intervention for adults with misophonia. The main questions it aims to answer are: Is the online intervention effective, compared to a waitlist control condition? Is the online intervention acceptable to use? Participants will be randomized into either the online …

18 years of age All Phase N/A
j jian zhang, phD

A Study of HDM2006 in Patients With Advanced Solid Tumor

This is a first-in-human (FIH) study to evaluate the safety and preliminary efficacy of experimental drug HDM2006 in patients with advanced solid tumors.

18 years of age All Phase 1
T Taylor Moss, MPH

The SolanoConnex Trial: Evaluation of a Mental Health Access Project

The goal of this study is to evaluate the effectiveness of the SolanoConnex.org program on help-seeking attitudes and help-seeking behaviors among users compared to a control group. This study will employ a randomized controlled trial design with two parallel arms. Participants in the intervention group will receive full access and …

18 years of age All Phase N/A

Long Covid (LC)-REVITALIZE - A Long Covid Repurposed Drug Study

The Long-Covid (LC)-Revitalize clinical study is testing repurposed drug treatments for Long Covid, involving adult participants from Brazil, Canada, Italy, Uganda, the United States, and Zambia. To qualify, participants must have had Covid-19 and experienced Long Covid symptoms for at least three months. The main goal of the study is …

18 - 65 years of age All Phase 3

A Study of FB1003 in Healthy and Osteoarthritis Pain Subjects

The purpose of Part 1 is to evaluate safety and tolerability of FB1003 when given subcutaneously to healthy participants. Blood tests will be done to examine blood exposure, concentration and half-life of FB1003 following administrations. For each participant, the study will last up to about 12 weeks for single ascending …

18 - 75 years of age All Phase 1
L Li Chen, Master

Hybrid Closed-Loop System in LADA Patients: A Randomized Trial

Based on the difficulties in blood glucose control among the Latent Autoimmune Diabetes in Adults (LADA) population and the deficiencies of previous studies, this research aims to conduct a clinical comparative study. The short-term blood glucose control effects of the closed-loop system and the combination of a conventional insulin pump …

18 - 70 years of age All Phase N/A

A Study of BL-B01D1 in Patients With Recurrent Glioblastoma

This is an open-label, multicenter, phase II study to evaluate the safety, efficacy, and pharmacokinetic characteristics of BL-B01D1 for Injection in patients with recurrent glioblastoma.

18 years of age All Phase 2

A Study of HDM2005 in Patients With Advanced Solid Tumor

This is a study evaluating the efficacy, safety, and pharmacokinetics ofHDM2005 in participants with metastatic solid tumors.

18 years of age All Phase 1
N Ning Li

A Study of CSCJC3456 in Patients With Advanced Malignant Tumors

This study is a multicenter, open phase I clinical study of dose escalation, cohort expansion study to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, and preliminary efficacy of CSCJC3456 in patients with advanced malignant solid tumors.

18 - 75 years of age All Phase 1

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