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a, a N Clinical Trials

A listing of a, a N clinical trials actively recruiting patients volunteers.

Found 11,315 clinical trials
D Danielle M Zerr, MD, MPH

Fecal Microbiota Transplantation as a Strategy to Eradicate Resistant Organisms

This protocol will evaluate fecal microbiota transplantation (FMT) as a strategy to eradicate intestinal colonization of extended-spectrum resistant (ESC-R) Enterobacteriaceae in pediatric patients. FMT will be performed on subjects with a history of at least one infection due to ESC-R Enterobacteriaceae. This protocol aims to determine the feasibility, safety, tolerability, …

7 - 21 years of age All Phase 1
M Meili Sun, PhD.

A Study to Evaluate HB0034 in Healthy Chinese Adult Participants

The aim of this study is to investigate the safety and tolerability of HB0034 in healthy subjects following a single dose or multiple dose.

18 - 45 years of age All Phase 1
L Lori A Brotto, PhD

Virtual Reality Exposure for Vaginismus: A Replicated Single-Case Design

Vaginismus is a sexual dysfunction characterized by involuntary tightening of the pelvic floor muscles, preventing vaginal intercourse. It is defined by an intense fear of vaginal penetration, leading to persistent difficulties with vaginal intercourse and gynaecological exams. Psychological factors play a significant role in vaginismus. If the pelvic floor muscle …

19 years of age Female Phase N/A

A Phase 1 Study of FZ008-145 in Healthy Subjects.

The study will be conducted in 5 parts: Part A (single ascending dose \[SAD\] in solution formulation), Part C (food effect \[FE\]), Part D (cold pressor test \[CPT\] to evaluate pain tolerance following single dose), and Part E (multiple ascending dose \[MAD\] in tablet formulation).

18 - 65 years of age All Phase 1
C Craig Ritchie, Professor, MD, PhD

A Study to Assess THN391 in Subjects With Alzheimer's Disease

This is a Phase 1b study to evaluate different doses of the drug and see whether a drug is safe and how it behaves in the body. THN391 has already been assessed in healthy people without Alzheimer's disease. This is the first study of THN391 in patients with Early Alzheimer's …

65 - 85 years of age All Phase 1

"Using a Multisite TENS SysteM to Improve Fibromyalgia-related Symptoms.

Fibromyalgia is a debilitating pain condition that is characterized by the chronic occurrence of pain affecting the musculoskeletal system, a sensitivity to pressure stimuli, and a low threshold to noxious stimuli. The topography of pain is widespread, although it could be more pronounced in some bodily regions. Besides pain, patients …

18 - 75 years of age All Phase N/A
J Juan C. Pedemonte, MD

Development of a Pharmacodynamic Model for Propofol in Older Adults

The goal of this pharmacodynamic study is to develop a model for Propofol administration for older adults (\>65 years). The main objective is to create a model based on a new pharmacodynamic parameter, derived from frontal electroencephalogram (EEG), to admininster Propofol in older adults. With this new model, the investigators …

65 - 99 years of age All Phase N/A
T Tianshu Liu

A Study of HDM2012 in Patients With Advanced Solid Tumor

This is a first-in-human (FIH) study to evaluate the safety and preliminary efficacy of experimental drug HDM2012 in patients with advanced solid tumors.

18 - 75 years of age All Phase 1

A Clinical Study of SPH9788 Tablets in Healthy Chinese Subjects.

The purpose of the study is to evaluate the safety of SPH9788 tablets in healthy subjects.

18 - 45 years of age All Phase 1
T Thomas Marron, MD PhD

A Study of Exercise and Pharmacologic Intervention on Systemic Inflammation

This is a study assessing the feasibility of performing an anti-aging intervention which is a combination of an exercise regimen, spermidine supplementation, and either rapamycin or lamivudine.

65 - 80 years of age All Phase 1

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