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Cardiac Disease Clinical Trials

A listing of Cardiac Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 1,818 clinical trials
P Paolo Denti

Transcatheter Interventions for Tricuspid Insufficiency in Italy

This is an observational, multi-center, retrospective and prospective study collecting data about patients undergoing transcatheter tricuspid valve interventions in a real world clinical environment. The aim is to report clinical characteristics, procedural results and short- and long-term outcomes of patients undergoing transcatheter tricuspid valve interventions in Italian centres.

18 - 100 years of age All Phase N/A
Z Zhiyun Xu, MD.

THE TRAVEL II TRIAL: Transcatheter Right Atrial-ventricular Valve rEplacement With LuX-Valve Via Jugular Vein

The trial aims to evaluate the safety and effectiveness of LuX-Valve transcatheter tricuspid valve and delivery system via jugular vein which are intended to use in symptomatic patients with severe tricuspid regurgitation and high surgical risk.

50 years of age All Phase N/A
U Ulrika Snygg-Martin, MD, PhD

Betalactam Pharmacokinetics in Endocarditis Patients

Infectious endocarditis (IE) is associated with mortality rates of 10-12%. Adequate antibiotic therapy is crucial for survival and is administered in high doses due to the severity of the disease. In most cases, beta-lactam antibiotics (e.g. ampicillin, penicillin G, cefotaxime or cloxacillin) are employed. A number of patient characteristics, such …

18 years of age All Phase N/A
K Kristine McGowen

Clinical Study of the inQB8 TTVR System

Prospective, multi-center study to assess safety and performance of the inQB8 MonarQ Tricuspid Valve Replacement System.

18 years of age All Phase N/A
C Chak Yu So

Application of Comprehensive Non-invasive Assessment To Phenotype Tricuspid Regurgitation

Tricuspid regurgitation (TR) is an increasingly recognized valvular heart disease associated with high morbidity and mortality. With the availability of various novel transcatheter tricuspid interventions, it is no longer considered a "forgotten valve." Heart failure with preserved ejection fraction (HFpEF) is a prevalent condition also characterized by high morbidity and …

18 years of age All Phase N/A
A Archil Chukhrukidze, PhD

Early Feasibility of 'Pivot Extend' for Tricuspid Regurgitation Treatment

This clinical trial aims to evaluate the safety and demonstrate the efficacy of treatment to improve tricuspid regurgitation (TR) symptoms in patients with severe and clinically symptomatic TR through long-term implantation of an investigational medical device. Determine the safety of long-term implantation of the investigational medical device "Pivot Extend" by …

18 years of age All Phase N/A
M MESSECA Clément

CBCT vs OPT on the Oral Health Status at 12 Months of Patients Hospitalized for Infective Endocarditis.

1\. Infective Endocarditis (IE) is a rare and serious disease with high morbidity and mortality; 2. Streptoccoci of oral origin are the second more frequent microorganisms responsible for IE; 3. Oral Infectious Foci (OIF) are underdetected using the current recommended clinical examination/Orthopantomogram (OPT) approach; 4. Cone Beam Computed Tomography (CBCT) …

18 - 100 years of age All Phase N/A
J Jong-Min Song, MD,PhD

Prospective Multicenter Registry of Patients With Mitral Stenosis Undergoing Percutaneous Mitral Balloon Commissurotomy

The goal of this observational study is to learn about the clinical outcomes after percutaneous mitral balloon commissurotomy (PMBC) for patients with mitral stenosis (MS) using nation-wide multicenter prospective registry including tertiary-referral hospitals in Korea. The main question it aims to answer is: What is the clinical outcomes after PMBC? …

18 - 89 years of age All Phase N/A
S Sara Jabeen

Laplace Early Feasibility Study - Canada

The objective of the study is to assess the safety and technical feasibility of the Laplace Transcatheter Tricuspid Valve Replacement (TTVR) System

60 - 90 years of age All Phase N/A
V Vilus Janusauskas, MD, PhD

Study of Transcatheter Tricuspid Annular Repair

The purpose of the study is to evaluate the safety and performance of the MIA Minimally Invasive Annuloplasty Device in patients with chronic functional tricuspid regurgitation.

18 - 85 years of age All Phase N/A

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