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Cardiac Disease Clinical Trials

A listing of Cardiac Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 1,879 clinical trials
A Amy Flowers

Precision Rehabilitation for Veterans With (HFpEF)

This study is being completed because there is conflicting information regarding the value of monitored exercise in patients with heart failure with preserved ejection fraction (HFpEF). The purpose of this study is to collect baseline information necessary for researchers to pursue a larger study evaluating how monitored exercise performed during …

18 years of age All Phase N/A
C Carolina Di Leone, Master degree

Inspiratory Muscle Training in Hospitalized Heart Failure Patients

Introduction Exercise intolerance is the most common symptom in patients with heart failure (HF), significantly impacting their quality of life and functional capacity. Muscle metabolism may be impaired due to sympathetic hyperactivation, systemic inflammation, and neurohormonal alterations, contributing to ventilatory inefficiency and exercise intolerance. Inspiratory muscle training (IMT) has been …

18 years of age All Phase N/A
Y Yvonne Millerick

Heart Failure Carer Support Programme: Implementation Testing in the UK.

Background Heart failure (HF) is widespread in the United Kingdom (UK). Many of these patients rely on support from family carers who are ill-prepared and supported for this role. These carers often experience poor mental and physical health because of their caring role. HEart faiLure carer support Programme (HELP) is …

18 years of age All Phase N/A
P Piotr Musialek, MD, DPhil

Simultaneous Cardiac Surgery and Micronet-covered Stent Carotid Revascularization in High Perioperative Stroke Risk Patients

Prospective, single-center, clinical registry of patients with symptomatic/critical carotid artery stenosis at risk of stroke coexisting with unstable or multivessel severe coronary artery disease and/or severe valvular heart disease undergoing endovascular treatment of carotid atherosclerosis using a mesh stent in combination with cardiac surgery (coronary artery bypass grafting (CABG) and/or …

18 years of age All Phase N/A

Using a Connected Application to Maintain Physical Activity After Cardiac Rehabilitation

Maintaining physical activity after cardiac rehabilitation has a major role in disease progression and patient prognosis. 6 months after the cardiac rehabilitation, we find during a nursing interview that many patients do not maintain regular physical activity. 1 year after cardiac rehabilitation, between 30% and 60% of patients do not …

18 years of age All Phase N/A
X Xin Wang

A Bioequivalence Study of Two Formulations of HRS-1893 Tablets in Healthy Participants

This study will investigate the bioequivalence between two formulations of HRS-1893 tablets. Safety and tolerability will also be assessed.

18 - 55 years of age All Phase 1
S Stefano Carugo, Principal Investigator

Genetic Characterization of Cardiomyopathies (POLICARDIOMIO2021)

Cardiomyopathy refers to a diverse group of myocardial diseases with multiple causes. In 1995, the World Health Organization classified cardiomyopathies into hypertrophic, dilated, restrictive, and mixed type. This classification is based on the pathophysiology of the disease. However, with rapid evolution of molecular genetics in cardiology, the American Heart Association …

18 - 80 years of age All Phase N/A
Y Yang Yan

Risk Stratification and New Early Prevention and Treatment Strategies for Patients With Cardiomyopathy (STRENGTH)

This study will include patients with different types of cardiomyopathy from multiple centers were prospectively enrolled in a retrospective study to establish a natural population cohort of cardiomyopathy patients. By collecting clinical data and biological samples from surgical patients, we will construct a prognostic system for cardiomyopathy, optimize risk stratification, …

18 - 80 years of age All Phase N/A
A Ashraf Mohamed Sewelam, M.B.B.Ch., M.S., M.D.

Cardioprotective Effects of Melatonin in Patients With Cardiomyopathy

The aim of current study is to: Evaluate the cardioprotective effects of melatonin in patients with cardiomyopathy.

18 years of age All Phase 3
C Chunjian Li, MD, PhD

A Novel Ferumoxytol-enhanced Cardiac Magnetic Resonance Imaging for the Detection of Intracardiac Thrombus

The incidence of thrombosis in ventricular aneurysm was reported to be 35%-40%, which may lead to systemic thromboembolism. Patients with ventricular aneurysm without detectable thrombus are not routinely treated with anticoagulation. Therefore, the accuracy of intracardiac thrombus detection has an important impact on clinical management decisions. Currently, transthoracic echocardiography is …

18 - 80 years of age All Phase N/A

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