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Migraine Clinical Trials

A listing of Migraine medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 182 clinical trials
S Shengyuan Yu

Phase II Trial of PRT-064040 Nasal Spray for the Treatment of Migraine in Adults

The purpose of this study is to learn about the efficacy and safety of PRT-064040 Nasal Spray versus placebo in the acute treatment of moderate or severe migraine.

18 - 75 years of age All Phase 2
A Alessandra Parisi, PHD

NEUROPSYCHOLOGICAL PROFILE CHARACTERIZATION IN PATIENTS WITH MIGRAINE: COGNITIVE FUNCTIONING AND PSYCHOLOGICAL VARIABLES

The overall objective is to define the neuropsychological profile of patients with migraine and evaluate its association with: psychological outcome measures (anxiety-depressive symptoms, pain catastrophizing, excessive worry, and coping strategies); the clinical profile of migraine; the prodromal, ictal, or interictal phase of the migraine attack; pharmacological therapy; and detoxification treatment …

18 - 65 years of age All Phase N/A
A Anne Hege Aamodt, MD PhD

The Nordic Chronic Migraine Trial of CGRP Monoclonal Antibody and Onabotulinumtoxin A Dual Therapy Compared to CGRP mAbs Monotherapy

Migraine is characterized by attacks of throbbing, moderate or severe headache, often associated with nausea, vomiting, and/or sensitivity to light and/or sound. Chronic migraine, which occurs in 1-2 % of the population is characterized by 15 or more headache days/month for more than 3 months and at least 8 days/month …

18 - 70 years of age All Phase 3
P Pamela M Rist, ScD

Cocoa Extract for Migraine Trial

The goal of this clinical trial is to assess the feasibility of recruitment and adherence to a high-dose cocoa extract supplement in individuals diagnosed with episodic migraine. The main questions it aims to answer are: Will we be able to enroll 114 participants during the recruitment period? Will participants take …

18 years of age All Phase N/A
M Myriam BENNANI

Treatment of Episodic Migraine With AURICular Neuromodulation

Migraine is a ubiquitous pathology affecting approximately 1 billion individuals and being the leading cause of morbidity worldwide before the age of 50. Migraine treatment consists of two main approaches: acute treatment to relieve headache symptoms and preventive treatment to reduce the frequency of migraine attacks by at least 50%. …

18 - 60 years of age All Phase N/A
C Christian Woeber, Prof.

Closed-loop RTMS for Short-term Migraine Prevention

Migraine is a prevalent and debilitating primary headache disorder, where patients suffer from disabling symptoms that usually consist of a moderate to severe headache lasting 4 to 72 hours, nausea and/or vomiting, phonophobia and photophobia. Transcranial magnetic stimulation (TMS) is a noninvasive technique that is considered to be safe. Repetitive …

18 - 65 years of age All Phase N/A
h hira jabeen

Comparative Effects of Theragun Percussion Therapy and Compression Therapy in The Patients With Migraine

The aim of this study is to compare the effects of Theragun Percussion therapy and Compression Therapy on pain, neck range of motion and quality of life in the patients with Migraine

18 - 65 years of age All Phase N/A
Y Yao Jie Xie, PhD

Tai Chi for the Prophylaxis of Episodic Migraine: the Efficacy Examination and Mechanism Exploration

The proposed study aims to examine the clinical efficacy of 24-week Tai Chi training in the prophylaxis of episodic migraine comparing with standard prophylactic medication in Hong Kong Chinese women, and to explore the mechanism of Tai Chi's intervention effect by examining the associations of changes in migraine features with …

18 - 65 years of age Female Phase N/A
H Håkan Ashina, MD

Substance P-Induced Migraine Attacks Without Aura

Substance P is a neuropeptide implicated in the pathogenesis of headache. This study investigates whether its administration can trigger migraine attacks in individuals with migraine without aura.

18 - 65 years of age All Phase N/A

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