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Migraine Clinical Trials

A listing of Migraine medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 159 clinical trials
C Christian Woeber, Prof.

Closed-loop RTMS for Short-term Migraine Prevention

Migraine is a prevalent and debilitating primary headache disorder, where patients suffer from disabling symptoms that usually consist of a moderate to severe headache lasting 4 to 72 hours, nausea and/or vomiting, phonophobia and photophobia. Transcranial magnetic stimulation (TMS) is a noninvasive technique that is considered to be safe. Repetitive …

18 - 65 years of age All Phase N/A
M Myriam BENNANI

Treatment of Episodic Migraine With AURICular Neuromodulation

Migraine is a ubiquitous pathology affecting approximately 1 billion individuals and being the leading cause of morbidity worldwide before the age of 50. Migraine treatment consists of two main approaches: acute treatment to relieve headache symptoms and preventive treatment to reduce the frequency of migraine attacks by at least 50%. …

18 - 60 years of age All Phase N/A
P Pamela M Rist, ScD

Cocoa Extract for Migraine Trial

The goal of this clinical trial is to assess the feasibility of recruitment and adherence to a high-dose cocoa extract supplement in individuals diagnosed with episodic migraine. The main questions it aims to answer are: Will we be able to enroll 114 participants during the recruitment period? Will participants take …

18 years of age All Phase N/A
S Shengyuan Yu

Phase II Trial of PRT-064040 Nasal Spray for the Treatment of Migraine in Adults

The purpose of this study is to learn about the efficacy and safety of PRT-064040 Nasal Spray versus placebo in the acute treatment of moderate or severe migraine.

18 - 75 years of age All Phase 2
Y Yemisrach Tadesse

Rimegepant as Preemptive Treatment for Predictable Trigger-Induced Migraine in Adult Patients in the US

Single-center, open label, prospective study conducted at Medstar Georgetown Headache Center. Men and woman ≥ 18 years old that are diagnosed with migraine with or without aura for at least 1 year, who report a reliable migraine trigger. Acceptable triggers for the study will include exercise, alcohol (less than one …

18 years of age All Phase 4
M Michael R Leonard

Effectiveness and Tolerability of Zavegepant for Acute Migraine Treatment Among Those Using CGRP Targeting Preventive Medications

Zavegepant (Zavzpret) is approved for the acute treatment of migraine with or without aura in the US. The purpose of this study is to investigate the effectiveness and tolerability of zavegepant for the acute treatment of migraine attacks amongst participants who are using calcitonin gene-related peptide (CGRP) migraine preventive treatments.

18 years of age All Phase 4
A Astrid Hjelholt, MD, PhD

Cabergoline for Episodic Migraine

The goal of this randomized, placebo-controlled, double-blind clinical trial is to evaluate the efficacy, safety, and tolerability of cabergoline for the prevention of episodic migraine in adults with 4-14 monthly migraine days (MMD). The main questions it aims to answer are: Does once-weekly cabergoline (0.5 mg or 1.0 mg) reduce …

18 years of age All Phase 2
D Danilo A Montisano, MD

Neuropsychological Profile Characterization in Patients With Migraine: Cognitive Functioning and Psychological Variables

The overall objective is to define the neuropsychological profile of patients with migraine and evaluate its association with: psychological outcome measures (anxiety-depressive symptoms, pain catastrophizing, excessive worry, and coping strategies); the clinical profile of migraine; the prodromal, ictal, or interictal phase of the migraine attack; pharmacological therapy; and detoxification treatment …

18 - 65 years of age All Phase N/A
E Elisa Debien

Neuro-Complex & Multi Supplements for Migraine Prevention

The goal of this prospective, monocentric, open-label, non-randomized and single arm study is to evaluate a reduction of migraine days per months (MDM) by 25% by using the combined supplementation with Neuro-Complex \& Multi after 8 weeks of product intake on participants with diagnosis of migraine meeting the criteria of …

18 - 75 years of age All Phase N/A

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