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Migraine Clinical Trials

A listing of Migraine medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 182 clinical trials
M Marian Papp, PhD - post-doc

Yogabased Movements for Primary Headaches (Migraine and/or Cluster Headache) - YOURHEAD - a Pilot Study

Migraine and/or Cluster Headache: Study Overview \*\Background:\\* Migraine and cluster headache are two primary headache disorders that significantly impact quality of life and functionality in those affected. According to the WHO's recurring burden of disease reports, migraine is among the neurological conditions responsible for the highest number of years lost …

18 - 65 years of age All Phase N/A
S Sergey Motov, MD

A Comparison of Nurtec ODT to Maxalt MLT-ODT in Adult ED Patients With Migraine Headache

Rimegepant (Nurtec) is an orally administered small molecule CGRP receptor antagonist with efficacy in the acute treatment of migraine. Rizatriptan benzoate (MAXALT), is a selective 5-hydroxytryptamine1B/1D (5-HT1B/1D) receptor agonist. Rizatriptan binds with high affinity to human cloned 5-HT1B and 5-HT1D receptors which leads to activation of these receptors results in …

18 - 65 years of age All Phase 4
C Chumgyili Li

Investigating the Impact of Acupuncture on the Quality of Life of Primitive Headaches Patients

Primary headache is one of the most common neurological diseases in modern society, which seriously affects the patient's quality of life. Although the use of painkillers can alleviate primary headache symptoms, it may also cause drug dependence. Therefore, alternative therapies that do not rely on drugs have attracted increasing attention …

18 years of age All Phase N/A

Migraines Accepted Laser Acupuncture Compared in Blood Test of MMP2 and CGRP

Aims To investigate the efficacy of laser-acupuncture for the severity of primary headache and comorbidities, and the Lab data examination. Methods In this hospital-based prospective single blind randomized sham-controlled study, patients over 18 years old with primary headache will be randomly divided into two treatment arms including laser-acupuncture and sham-controlled …

18 years of age All Phase N/A
A Ayesha Rehman

Bilateral Middle Meningeal Artery Lidocaine Infusion for Chronic Debilitating Migraines

The main purpose of this study is to evaluate the effectiveness of a new treatment in improving chronic migraine symptoms. This treatment involves a targeted lidocaine infusion into blood vessels in the skull to numb pain receptors, potentially leading to improvements in chronic migraine intensity, frequency, and duration.

18 - 75 years of age All Phase 2
M Melanie K Choe, BS

Fremanezumab Treatment of Migraine in Women With Menstrual Migraine Ages 18-45

The goal of this clinical trial is to learn about how a migraine prevention medicine works for people who have migraines/headaches with their menstrual period. The study includes people ages 18 to 45 who have been diagnosed with migraine and who have a migraine with their menstrual period or those …

18 - 45 years of age Female Phase 4
S Simple Futarmal Kothari

Trial Designs for Evaluating Migraine Treatment

The study aims to estimate treatment effects in randomized controlled trials (RCT) and a balanced placebo design (BPD) to specify how contextual and psychological factors interact in acute migraine treatment and influence adverse event occurrence. Using a clinical within-subjects design, patients with episodic migraine will receive six treatment conditions in …

18 - 65 years of age All Phase N/A
S Samar Ashrafi, PharmD

Effectiveness of Magnesium in Addition to Prochlorperazine for the Treatment of Migraines

The purpose of this research study is to find out if using magnesium in addition to prochlorperazine will help reduce your migraine pain.

18 years of age All Phase 3
J Joel Brown

Migraine in Adolescents

Aim 1. To identify psychophysical and neural factors predicting migraine onset in adolescents Aim 2a. To determine hormonal, psychophysical, and neural changes associated with migraine onset. Aim 2b. To identify the temporal relationships between hormonal, psychophysical, and neural changes preceding vs. following migraine onset. Aim 3. To identify psychophysical and …

10 - 13 years of age All Phase N/A

Qudexy XR for the Prevention of Migraine in Children 6 to 11 Years Old

A Phase 4 study to evaluate Qudexy XR for the prevention of migraine in children 6 to 11 years of age.

6 - 11 years of age All Phase 4

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