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Pain Clinical Trials

A listing of Pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,817 clinical trials
O Olaf Gräbel, MD, PhD

Placebo Effect In Spinal Cord Electrical Stimulation for Pain

Objective: To evaluate if spinal cord stimulation (SCS) performs better than placebo (no stimulation) in the long term to reduce persistent neuropathic leg pain refractory to medication and other conservative treatments in patients who have undergone lumbar spinal surgery. Study design: Multicenter, double blind, randomized, sham-controlled trial. After a positive …

18 - 70 years of age All Phase N/A
T Tahereh Naeimi, MD

Evaluation of TENEX for Greater Trochanteric Pain Syndrome (GTPS)

The objective of this study is to evaluate how an ultrasound-guided percutaneous procedure, TENEX, can help people with chronic hip pain resulting from a condition called Greater Trochanteric Pain Syndrome (GTPS) and to characterize the efficacy of percutaneous tenotomy (PUT) using TENEX®, a device used for the treatment of various …

30 - 90 years of age All Phase N/A
A Alexander L Green, PhD

Efficacy of Pain Intervention With Deep Brain Stimulation Neuromodulation

The goal of this clinical trial is to learn if deep brain stimulation (DBS) works to treat severe pain following a stroke in adults. It will also learn about the safety of deep brain stimulation. The main questions it aims to answer are: Does DBS lower the pain score in …

21 years of age All Phase N/A
M Maarten Moens, Prof, Dr.

Intrathecal Therapy Versus Standard Care for Severe Cancer Pain

Approximately 66% of patients with advanced cancer experience pain, which is often inadequately controlled and associated with a decline in health-related quality of life (HRQoL). Conventional pharmacologic management, ranging from simple analgesics to strong opioids, is frequently limited by insufficient efficacy and systemic side effects. Intrathecal drug delivery (IDD) offers …

18 years of age All Phase N/A

TENS Versus Ultrasound With Exercise for Mechanical Neck Pain.

This randomized clinical trial aims to compare the effectiveness of Transcutaneous Electrical Nerve Stimulation (TENS) and therapeutic ultrasound, both combined with therapeutic exercises, in the management of mechanical neck pain. A total of 44 participants male and female both with mechanical neck pain will be randomly allocated into two equal …

18 - 45 years of age All Phase N/A
H Hio Teng Leong

Electroacupuncture on Neck Muscle Stiffness in Chronic Neck Pain

This randomized, single-blind, placebo-controlled clinical trial aims to investigate the immediate physiological effects of a single session of electroacupuncture (EA) on neck muscle stiffness in individuals with chronic neck pain. While acupuncture is a widely used complementary therapy for musculoskeletal pain, high-quality, objective evidence demonstrating its immediate effects on muscle …

18 - 65 years of age All Phase N/A
M Melanie Morin, PhD

Efficacy of Dry Needling in Reducing Pain During Sexual Intercourse

Chronic vulvar pain is a highly prevalent and debilitating condition affecting up to 16% of women. The most common subtype of vulvar pain, provoked vestibulodynia (PVD), is characterized by a sharp pain at the entry of the vagina in response to pressure or attempted vaginal penetration. Women with PVD not …

18 - 45 years of age Female Phase N/A
A AKM Mahzabin Akhtaruzzaman, MD

Efficacy and Safety of Mirogabalin in Diabetic Peripheral Neuropathic Pain

The goal of this clinical trial is to learn if drug Mirogabalin works to treat diabetic peripheral neuropathic pain in adults. It will also learn about the safety of the drug Mirogabalin. The main questions it aims to answer are: Does drug mirogabalin reduce neuropathic pain intensity? Is the drug …

40 years of age All Phase 4

Medullary Stimulation for the Treatment of Refractory Neck Pain (S2M)

Number of centres planned : 1 (CHU Nantes) Design : Randomized, Prospective Planning of the study : Total duration: 34 months Recruitment period: 24 months. Follow-up time per patients : 7-10 months Expected number of cases : 12 Treatment, procedure, combination of procedures under consideration : During the study, patients …

18 - 85 years of age All Phase N/A

Use of Virtual Reality in Pain Management in Pediatric Oncology

DOREVI is a monocentric randomized controlled study that will evaluate the efficacy of virtual reality helmets for pain prevention during invasive care on 78 oncologic pediatric patients. Two groups of children (between 6 and 11 and between 12 and 18 years old) will be randomized to use helmet plus standard …

6 - 18 years of age All Phase N/A

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