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Pain Clinical Trials

A listing of Pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,817 clinical trials

Transcutaneous Electrical Nerve Stimulation for Endometriosis-related Chronic Pain

The study evaluates the effect of TENS (transcutaneous electrical nerve stimulation) as add-on treatment compared with conventional analgesic treatment in patients with endometriosis-related chronic pain. Patients with frequent pain and high pain intensity will be randomized to additional treatment with TENS or conventional treatment for 8 weeks to evaluate the …

18 - 100 years of age Female Phase N/A
C Clifton Carey

Comparison of Patient-reported Pain After Initial Archwire Placement

Three different types of 'archwires' can be used in Orthodontic treatment, wire choice is decided by treating Orthodontist based on professional preference since research shows that all types are equally effective. It is possible that one type of wire engenders more patient discomfort. This study will compare the discomfort levels …

12 years of age All Phase N/A

Study of RTMS Analgesic Effect in Chronic Neuropathic Pain,

The purpose of this study is to compare the analgesic effectiveness of three modes of repetitive Transcranial Magnetic Stimulation (rTMS) in chronic neuropathic pain: Classical rTMS stimulation Deeper rTMS stimulation Sham rTMS stimulation

18 - 80 years of age All Phase N/A
M Michael Shalaby, MD

Genicular Nerve Block for Knee Pain in the ED

Patient with atraumatic knee pain without a large knee effusion on x-ray will be randomized to receive either a genicular nerve block (GNB) or standard of care in the emergency department.

18 years of age All Phase N/A
A Amélie Apinis-Deshaies Research Coordinator

Cannabidiol After Multi-Trauma for Pain and Opioid Therapy

The aim of this project is to investigate the therapeutic potential and safety of acute Cannabidiol (CBD) treatment on longitudinal pain symptoms, and to assess potential interactions with pain mediators including opioids and sex on CBD treatment response. To this end, this research protocol proposes a comprehensive translational approach including …

18 - 70 years of age All Phase 2
H Hesham Rashid, Professor

Intra-Articular Dexmedetomidine: A Treatment for Chronic Knee Pain

Chronic knee osteoarthritis (KOA) is a painful condition with limited treatment options. Non-pharmacological approaches often fall short, leading to decreased quality of life. Ozone therapy, a simple and affordable treatment, has shown promise for pain relief. Dexmedetomidine (DEX), a sedative and analgesic, has been used successfully as an adjuvant to …

40 - 75 years of age All Phase N/A

Efficacy of Suprascapular Radiofrequency Ablation in Hemiplegic Shoulder Pain

Stroke, one of the most important causes of disability and death in the world, is an acute focal deficit of the central system caused by vascular origin such as cerebral infarction, intracerebral haemorrhage and subarachnoid haemorrhage. Hemiplegic shoulder pain, which is one of the most common complications after stroke, is …

18 years of age All Phase N/A
P Paul Gerdhem, MD, PhD

Fusion or Not - a Study on Low Back Pain

Problems from the musculoskeletal system are one of the most common reasons for disability and sick leave. These problems include low back pain. Low back pain affects as many as 8 out of 10 individuals at some point in life. In most people it is quickly transient with little, or …

25 - 65 years of age All Phase N/A

An Acupuncture Study for Cancer Survivors With Joint Pain

The purpose of this study is to see whether acupuncture is a practical (feasible) treatment for cancer survivors with joint pain.

18 years of age All Phase N/A
D Daniel Torrez, BS

(2R,6R)-Hydroxynorketamine for the Treatment of Neuropathic Pain

The goal of this randomized double blind three way (1:1:1) cross over clinical trial is to evaluate the effectiveness and duration of analgesia of a single infusion of (2R,6R)-HNK 0.5mg/kg compared with ketamine 0.5mg/kg and saline with a 5-week interval between treatments on pain, pain qualities, physical function, pain interference, …

18 - 75 years of age All Phase 1/2

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