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Pain Clinical Trials

A listing of Pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,824 clinical trials
K Kelly M Naugle, PhD

Exploring the Acute and Dynamic Relationships Between Movement and Pain in Older Adults With Musculoskeletal Pain

The purpose of this research study is to evaluate the effect of brief bouts of intermittent walking on bodily pain, pain during movement, and how the body adapts to musculoskeletal pain in older adults.

55 - 85 years of age All Phase N/A
T Tonny S Luggya, MBChB, MMed

Multimodal Analgesia Utilization and Acute Postoperative Pain After Major Surgery at Mulago National Referral Hospital

The goal of this observational study is to understand the approach to pain management before, during, and after surgery at Mulago National Referral Hospital. It is focussed on adult patients undergoing major surgery. The main questions it aims to answer are: How often are combinations of pain medications utilised before, …

18 years of age All Phase N/A
G Ganesan Baranidharan

Spinal Cord Stimulation for Chronic Abdominal Pain Patients

Chronic abdominal pain is a common disorder that can have significant impact on the lives of patients. Treatment options include medication which can have limited effectiveness, be associated with side effects and may lead to tolerance and dependency. Spinal cord stimulation (SCS) is a minimally invasive, therapeutic option for managing …

18 - 130 years of age All Phase N/A
K Karen Van Manen

Pivotal Study on the NOVABLOC System for Patients Undergoing Primary Total Knee Arthroplasty

Multi-center, randomized, blinded, sham-controlled study to determin the safety and efficacy of the NOVABLOC system on post-operative pain in patients undergoing TKA procedures.

21 years of age All Phase N/A
M Mesut YILMAZ, Dr.

Multisensory Methods and Patient Comfort in Thyroid Biopsy

This quasi-experimental study aims to determine the effect of watching an therapeutic video on patients' pain, anxiety, and comfort levels during thyroid biopsy procedures. The study will be conducted in the interventional radiology unit of Muş State Hospital between July 30, 2025, and August 28, 2026. A total of 68 …

18 - 90 years of age All Phase N/A

A Study of Single and Multiple Doses of HRS-6257 in Healthy Subjects

This is a phase I, randomised, single-blind placebo-controlled, 2-part study to assess the safety, tolerability, pharmacokinetics, pharmacodynamics and food effect of single and multiple oral doses of HRS-6257 in healthy volunteers.

18 - 55 years of age All Phase 1
F Fang Luo, M.D.

Pre-emptive Scalp Infiltration with Triamcinolone Acetonide Plus Ropivacaine for Post-Craniotomy Pain in Children

At present, pediatric postoperative analgesia has not been fully understood and controlled, particularly craniotomy surgery. On the one hand, professional evaluation of postoperative pain for young children is difficult; on the other hand, the particularity of craniotomy adds (such as consciousness obstacle, sleepiness, et al) disturbance to the pain assessment …

2 - 12 years of age All Phase 4
A Antoine Roger, MD

Epsom Salt Compresses to Relieve Perineal for Postpartum Care: a Clinical Trial

The goal of this clinical trial is to determine if topical application of compresses soaked in 25% magnesium sulfate on painful perineum after birth is effective to alleviate pain. Researchers will compare this treatment to a placebo, compresses soaked in water. Participants will be invited to use their compresses if …

18 years of age Female Phase 2
M Miranda McMillan

The Impact of Gender Affirming Hormone Therapy on Pain In Gender Minority Adults

TRANSPIRE is an observational study of \~200 individuals who (1) will be initiating gender-affirming hormone therapy (GHT) or (2) are gender minority individuals who do not use GHT. The primary outcome will be to identify how the presence of chronic pain changes overtime with GHT through the use of surveys, …

18 - 50 years of age All Phase N/A
J Jane Kelly

A First in Human Study of TT5 in Single and Multiple Ascending Doses in Healthy Volunteers and Surgical Patients

This study is a First in Human, three-parts, double-blind, randomized, placebo-controlled, single and multiple ascending dose study. The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of TT5 at different doses in healthy and surgical participants.

18 - 55 years of age All Phase 1

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