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Pain Clinical Trials

A listing of Pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,824 clinical trials
B Bethany Hunt, BA

The Warmth, Anticipation, Sensation, Aversion, and Body-part Imaging Study

This functional magnetic-resonance imaging study of the brain will feature a within-subject crossover design to investigate the effects of a placebo cream on painful thermal stimulation rendered upon eight body sites. The investigators aim to 1.) improve the understanding of how the brain represents thermal pain responses somatotopically (i.e., across …

18 years of age All Phase N/A
O Olivia Baryluk, BS

Virtual Reality for Pain Management in Burn Patients

This study is a randomized proof-of-concept study to assess the efficacy of Virtual Reality (VR) vs standard of care in 50 adult patients in the New York Presbyterian Burn Unit. The participants who are randomized to receive the virtual reality intervention will also receive opioids, which is the standard of …

8 years of age All Phase N/A
J Julia C Finkel, MD

Measuring Analgesic Interventions

It is generally recognized that pain assessment and management especially in newborns, children and other nonverbal populations is an unmet need. According to the American Medical Association, "the pediatric population is at risk of inadequate pain management, with age-related factors affecting pain management in children. Children are often given minimal …

7 - 21 years of age All Phase N/A
M Mary E McDuffie, RN BSN

Defense and Veterans Center for Integrative Pain Management (DVCIPM) Pain Registry Biobank

This Pain Registry Biobank is a prospective cohort design study whereby data (PASTOR survey, blood and saliva specimens, clinical data) is collected from participants in a longitudinal fashion with continual enrollment.

18 - 80 years of age All Phase N/A
J Jessica Florig, MPH

Study of Low-intensity Focused Ultrasound Effects on Heat Evoked fMRI Signals

Study aims to examine the effects of noninvasive brain stimulation on brain signals. This insight may have potential clinical implications for addiction, pain, and mental health populations. Participants will receive MRI and CT imaging. Participants receive low-intensity focused ultrasound (LIFU) to temporarily change brain activity. Participants then receive fMRI scans …

18 - 65 years of age All Phase N/A
P PLAN lab

Oklahoma Study of Native American Pain Risk III: Stress and Resilience

The goal of this observational study is to learn about the relationship between environmental structural racism and discrimination and chronic pain risk in Native American adults. The main questions it aims to answer are: How does environmental structural racism and discrimination affect chronic pain-promoting mechanisms in Native Americans? What psychosocial …

18 years of age All Phase N/A
L Lauren E Nieder, MSPH

The Potential of Oxytocin to Reduce Opioid Abuse Liability and Pain Among Older Adults

Some research suggests that administration of oxytocin with oxycodone may reduce its abuse liability and improve its ability to reduce pain. In a 6-session laboratory study, we will be evaluating the effects of oxycodone and oxytocin (combined and separately, across sessions) on experimentally-induced pain, subjective effects, and decision-making.

45 - 85 years of age All Phase 0
K Ke Ma, PhD

A Clinical Study on the Efficacy of Cognitive Distraction Focus Relaxation Therapy Based on MR

A prospective, single blind, randomized, parallel controlled trial was conducted to evaluate the analgesic effect and safety of MR based "cognitive distraction focus relaxation therapy" in patients clinically diagnosed with chronic moderate to severe pain

18 - 85 years of age All Phase N/A
A Ayse Ulucay, MD

Contrast and Anesthetic Level With Lumbar Erector Spinae Plan (ESP) Block

As per usual care for spine surgery, participants will have their back cleaned with alcohol and a needle will be placed using ultrasound for the ESP block. Through the needle, a small catheter will be placed in the participants back and the needle removed. Approximately one hour prior to the …

21 - 75 years of age All Phase N/A
A Ayşe Kahraman, Assoc Prof

The Effect of Storigami Method on Pain, Fear and Anxiety Levels Associated With Peripheral Intravenous Catheterisation in Children

The aim of this study was to determine the effect of storigami method on reducing pain, fear and anxiety of children in peripheral intravenous catheter applications in children aged 6-9 years who were hospitalized in the pediatric health and diseases clinic.

6 - 9 years of age All Phase N/A

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