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Pain Clinical Trials

A listing of Pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,825 clinical trials
B Birute Gedrimaite

Low-Dose Naltrexone for the Treatment of Complex Regional Pain Syndrome

The investigators are testing treatment with low-dose naltrexone (LDN) for symptom relief of complex regional pain syndrome (CRPS). Study participants will be randomly assigned to receive either LDN or placebo for a period of several weeks. During this period participants will be asked to attend either in-person or virtual study …

18 - 70 years of age All Phase N/A
J Javeria Aslam, MS

Effects of Core Stability Exercises in Postpartum Female With Lumbopelvic Pain

The study aims to determine the effect of core stability exercise through using fully immersive virtual reality in postpartum female with lumbopelvic pain. This study will be randomized clinical -trial and will be conducted at Shalamar Institute of health sciences in 1 year after the approval by institutional review board. …

20 - 40 years of age Female Phase N/A
M Malin Ernberg

Peripheral TMD Pain Mechanisms and the Effect by Botulinum Toxin A

The goal of this clinical trial is to investigate the effect of botulinum toxin on neurons' plasticity in the masseter muscle in humans with and without painful myogenous temporomandibular disorders (TMDM). The main questions it aims to answer are: does treatment with botulinum toxin alter gene expressions, epigenetic signatures, and …

20 - 45 years of age Female Phase 2
R Ravi Naidoo, MD, PhD

Distraction as Treatment for Pain in Children in Resource-scarce Settings

Pain alleviation in pediatric patients can be challenging for medical professionals working in resource scarce settings due to limited availability of medication, monitoring equipment, or training in this field of expertise. This poses the need for a readily available tool for pain reduction that does not rely on expensive equipment …

7 - 12 years of age All Phase N/A
J Junwei Hao, PhD,MD

Transcranial Electrical Stimulation for Treating Chronic Pain in Inflammatory Demyelinating Diseases

Non-invasive neurostimulation can effectively improve patients' symptoms and has shown good therapeutic efficacy in alleviating the symptoms of IIDDs (Inflammatory Immune-mediated Demyelinating Diseases). However, some patients have not achieved the desired results, which may be due to individual differences in neural responsiveness . Therefore, this study aims to assess the …

18 - 65 years of age All Phase N/A
C Christian cv Vetter, MD

Endometriosis and Pain Treatment by Intraoperative Administration of Low-dose Ketamine

RCT comparing intraoperative administration of low-dose ketamine during laparoscopic endometriosis operation and the postoperative pain outcome

18 years of age Female Phase 4
M Maha Ali Mirza, BDS

Postoperative Pain Comparison of Two Root Canal Sealers in Irreversible Pulpitis

This study, approved by the Institutional Ethics Review Committee, AFID (Annex "A"), will involve 62 eligible patients from the Operative Dentistry Department, Armed Forces Institute of Dentistry. Patients (and their guardians) will receive a detailed explanation in Urdu, and written informed consent will be obtained (Annex "B"). Study Design: Randomized …

20 - 40 years of age All Phase 2
S Syed Shakil ur Rehman

Sound Sine Wave And Standard Physiotherapy In Mechanical Low Back Pain

The study design will be a randomized clinical trial (RCT). Sampling technique will be nonprobability convenience sampling. Data will be collected from KKT orthopedic spine center Lahore. Participants will be divided into 2 groups. Group A will receive Sound wave treatment protocol and standard physiotherapy treatment protocol , Group B …

18 - 45 years of age All Phase N/A
V VALERIA MARTINEZ, MD

The Role of Peripheral Afferents in Modulating Post-stroke Central Pain

Central post-stroke pain (CPP) is extremely difficult to relieve and responds very poorly to analgesics targeting neuropathic pain, probably because the mechanisms underlying this pain remain poorly understood. Stroke pain is traditionally considered to be of central origin and related to changes in the spinal cord and/or brain nociceptive systems. …

18 years of age All Phase 3
E Emma Hertel

Exploration of Gait Biomechanics and Muscle Pain of the Lower Extremity

This interventional study aims to test gait biomechanics in healthy individuals with and without experimental muscle pain in the lower extremities. The study aims to: Examine how experimental muscle pain in different types of muscles (ankle plantar-flexion, knee extension, and flexion muscles) affects kinematics, kinetics, and muscle activation Participants will …

18 - 45 years of age All Phase N/A

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