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Pain Clinical Trials

A listing of Pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,747 clinical trials
H Hüdanur Coşkun, M.D.

Effects of Close Follow-up on Patients With Low Back Pain

This study will include patients aged 18-65 with subacute or chronic mechanical low back pain who apply to the Physical Medicine and Rehabilitation Clinic. The age, gender, body mass index, duration of low back pain, smoking status, and educational status of the patients included in the study will be recorded. …

18 - 65 years of age All Phase N/A
M Malgorzata Domagalska, Ph.D.

Dexamethasone Vs. Dexmedetomidine for ESPB in Pain Management After Knee Arthroplasty

Effect of perineurial dexamethasone and dexmedetomidine on erector spinal plane block duration for knee arthroplasty

18 - 100 years of age All Phase 4
L Lucy Chen, M.D.

Virtual Reality Guided Acupuncture Imagery Treatment for Chronic Low Back Pain

Testing the effect of Virtual Reality - guided imagery acupuncture

18 - 75 years of age All Phase N/A
M Mindy Rodden, PhD, RN, CPNP-AC

Oral Acetaminophen for Post-Op Pain Management in Bariatric Surgery Patients

Adult patients with morbid obesity who have had Roux-en-Y gastric bypass (RYGB) or laparoscopic sleeve gastrectomy (LSG) surgery have impaired drug metabolism. There is a paucity of information available on how these patients metabolize acetaminophen post operatively and if drug preparation has any effect on achieving adequate pain control. The …

18 years of age All Phase 2
S Samar R. Amin, lecturer

Effect of Sedation After Ultrasound-Guided Spinal Anesthesia on Back Pain

This study will evaluate whether giving sedation before spinal anesthesia, when performed with ultrasound guidance, reduces the risk of developing back pain after surgery. Spinal anesthesia is commonly used but may cause discomfort or persistent back pain in some patients. By comparing standard techniques, ultrasound guidance, and sedation, we aim …

18 - 65 years of age All Phase N/A
F Fadi MQ Al Zoubi, PhD

Expressive Art Therapy for Elder Adults With Chronic Low Back Pain

This research project aims to assess the feasibility of expressive art therapy for elderly adults with chronic low back pain and to evaluate the preliminary efficacy of combining art therapy with exercise intervention. Additionally, the study will investigate facilitators and barriers to participation. A mixed-methods approach will be employed, including …

60 years of age All Phase N/A
M Maria Groza

Objective Integrated Multimodal Electrophysiological Index for the Quantification of Visceral Pain

The objectives of the study are to 1) Conduct telemetric biosignals (EDA, ECG, and EMG) recording in healthy controls and IBS participants experiencing cutaneous and visceral pain; and 2) Validate the OIME index as a biomarker for quantifying pain in IBS participants and its capability to assess the treatment of …

18 - 50 years of age All Phase N/A
U Umar Aulia, AB

The Erector Spinae Plane Block For Gastrointestinal Malignancy Pain Treatment (EGIPT)

This study will target patients with gastrointestinal (GI) malignancy who present to any of 4 Penn Medicine emergency departments (EDs) with intractable abdominal pain. We will offer eligible patients an erector spinae plane block (ESPB), a regional anesthesia technique which is already offered to such patients in the ED at …

18 years of age All Phase N/A
M Mahmoud M Metwaly, MD

Pressure Pain Tolerance in Relation to Balance and Strength in Children

Sickle cell disease (SCD) is the most frequent life-threatening genetic hemoglobinopathy in the world and occurs due to the synthesis of abnormal hemoglobin S (HbS).Cells with sickle cell hemoglobin are stiff and sticky. When they lose their oxygen, they form into the shape of a sickle or crescent. This can …

9 - 14 years of age All Phase N/A
R Rituparna Maiti, MD

Effect of Venlafaxine Versus Dosulepin in Pain Predominant Somatic Symptom Disorder

Somatic symptom disorder (SSD) is marked by persistent physical complaints, often involving pain, alongside excessive thoughts or behaviors related to health, which substantially disrupt daily functioning. The underlying mechanisms of SSD are multifaceted. The serotonin hypothesis links low serotonin levels to the development of somatic symptoms, while the cortisol hypothesis …

18 - 65 years of age All Phase 4

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