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Surgery Clinical Trials

A listing of Surgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,630 clinical trials
B Bryan Carroll, MD, PhD

Effects of Lavender Aromatherapy on Patient Anxiety During Mohs Micrographic Surgery

This study aims to improve patient comfort by exploring the potential of lavender aromatherapy in reducing anxiety and unpleasant odor perception during Mohs Micrographic Surgery (MMS). Lavender has been widely studied for its sedative-like properties and calming effects, both in medical and dental settings. By investigating the impact of lavender …

18 years of age All Phase N/A
E EMBRACE study co-ordinator

Cross Bracing Protocol Versus Surgery for Acute Anterior Cruciate Ligament Rupture

The aim of the EMBRACE clinical trial is to compare outcomes (knee pain, symptoms, function and quality of life) between people with anterior cruciate ligament (ACL) rupture who are managed with either a novel bracing protocol (Cross Bracing Protocol), or with ACL reconstruction surgery. The main question that the trial …

16 - 40 years of age All Phase N/A
J Junlong Zhuang, MD

Radiotherapy or Surgery Combined With Intense Androgen Deprivation Therapy for mCRPC

This multi-center randomized controlled phase II trial was carried out in several hospitals in China to evaluate the efficacy and safety of radiotherapy or radical prostatectomy combined with intense androgen deprivation therapy for newly diagnosed metastatic prostate cancer.

18 - 80 years of age Male Phase 2
O Omur Ercelen, Professor

PECS-II vs ESP in Nociception Level Index Guided Breast Surgery

Background Breast surgery is often associated with significant perioperative pain. While systemic opioids are commonly used, their side effects (nausea, vomiting, respiratory depression, delayed recovery) have encouraged the adoption of regional anesthesia techniques for better analgesia and reduced opioid requirements. PECS-II and Erector Spinae Plane (ESP) blocks are two effective …

18 - 80 years of age Female Phase N/A
E Eleni Gkika

Immunochemotherapy, Surgery or Chemoradiation, and Durvalumab for Stage IIIA/B NSCLC

The hypothesis of the study is that induction immunochemotherapy, followed by surgery or chemoradiation and consolidation Durvalumab immunotherapy, can significantly improve event-free survival in patients with resectable or borderline resectable NSCLC at stage IIIA/B compared to existing treatment methods.

18 - 74 years of age All Phase 2
X Xavier Sala-Blanch, MD

Geniculate Nerve Block Versus Adductor Canal Block for ACL Reconstruction Surgery

Anterior cruciate ligament repair (ACL) surgery presents moderate to severe pain during the inmediate postoperative period and the first days after surgery. In addition, due to the interest of surgeons and patients for early reinstatement, the use of blockages that decrease the strength of the quadriceps is avoided. Therefore, in …

18 - 50 years of age All Phase N/A
C Chiun Ho Hou, Ph.D

Anxiety and Surgery Satisfaction for Cataract Patient With Different State Anxiety

This study aims to explore the effects of anxiety traits on pain, anxiety, and anesthesia satisfaction in patients undergoing cataract surgery under topical anesthesia. On the day of recruitment, patients will complete the BAI, STAI-S, and STAI-T anxiety questionnaires to assess baseline anxiety levels. Thirty minutes before the surgery, patients …

18 - 80 years of age All Phase N/A
R Robert Molloy, MD

Effectiveness of Exparel Anesthetic Administered by the Surgeon During Knee Surgery

Intra-articular Posteromedial Surgeon Administered (IPSA) Block in this study describes a new type of medical procedure where a surgeon provides anesthetic medication directly into a specific area inside a knee joint to numb the pain during knee surgery. Intra-articular refers to inside of knee joint, posteromedial refers to the back …

years of age All Phase N/A
E Ernestas Šileika, MD

Total Neoadjuvant Therapy and Organ Preservation Versus Surgery for Rectal Cancer.

This study hypothesizes that approximately 50% of rectal cancer patients can preserve their rectum using a watch-and-wait strategy if they achieve a complete or near-complete clinical response to total neoadjuvant therapy (TNT). The objective is to determine whether the complications, quality of life, and survival rates of rectal cancer patients …

18 years of age All Phase 2/3

Patient-led Follow-up from Home After Surgery for Colorectal Carcinoma

The primary goal of the patient-led follow-up from home, is the improvement of quality of life and the reduction of stress in patients, while obtaining a more complete picture of their health status. A series of assessments are performed in the home setting: Blood withdrawal for CEA determination Quality of …

21 years of age All Phase N/A

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