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Surgery Clinical Trials

A listing of Surgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,630 clinical trials
G Guillaume Besch, M.D., Ph.D.

Femoral Versus Radial Invasive Arterial Pressure Monitoring in Cardiac Surgery Patients

Background: Acute circulatory failure, often presenting as arterial hypotension, is a major contributor to postoperative morbidity and mortality. Accurate blood pressure (BP) monitoring is essential for timely therapeutic intervention, particularly in patients undergoing major surgery. Among invasive BP measurement sites, the radial artery is commonly used due to its accessibility …

18 - 80 years of age All Phase N/A
G Gabriela E Halder, MD, MPH

A Telehealth Intervention to Increase Patient Preparedness for Surgery in Latinas

There are 3 aims of this study. In Aim 1 community patient partners will be enrolled to help guide the research being performed in all of the aims. Investigators will also administer a survey that will help determine factors associated with surgical preparedness. In Aim 2 investigators will develop an …

18 years of age Female Phase N/A
M Mitch Gheorghiu

Bicuspid Aortic Valve Replacement: Evaluation of Transcatheter Versus Surgery-Pilot Trial

The study protocol is a randomized trial of standard of care therapies for severe aortic stenosis (AS) in patients with a bicuspid aortic valve (BAV). Namely, the therapies to which patients will be randomized will be transcatheter aortic valve replacement (TAVR) or surgical aortic valve replacement (SAVR), in patients deemed …

50 years of age All Phase N/A
B Bart CT van de Laar, MD

Sentinel Node and Organ-sparing Surgery in Stage I Colon Carcinoma

The aim of this study is to reduce the need for segmental colonic resection and its associated morbidity and mortality in patients with high-risk pT1 and low-risk pT2 colon cancer following endoscopic resection, by performing an endoscopic-assisted laparoscopic/robotic wedge resection of the residual tumor or scar, along with sentinel node …

18 years of age All Phase N/A
C Cristiana Griffoni, PhD

Which Markers of Musculoskeletal Health Can Explain Complications in Spinal Surgery?

The present study is related to the project "ORTHOSPINE FITNESS: WHICH MARKERS OF MUSCULOSKELETAL HEALTH CAN EXPLAIN COMPLICATIONS IN SPINE SURGERY?", winner of the Ministry of Health Call, financed by the European Union, "M6/C2_CALL 2023", Project Code " PNRR- MCNT2-2023-12378098", Call section "Non-chronic chronic diseases transmissible diseases (MCnT2) with a …

18 years of age All Phase N/A
S Stefan D Holubar, MD/MS

Pyridostigmine Efficacy and Safety for Treatment of Ileus After Colorectal Surgery

A double blind, placebo controlled, randomized control trial studying the safety and efficacy of pyridostigmine as a rescue therapy for postoperative ileus. Patients who undergo elective colorectal resection with or without creation of an ostomy, and subsequently develop postoperative ileus will be eligible for enrollment. Patients will be randomized to …

18 years of age All Phase 2/3
Y Youping Liu, PhD.

Endoscopic Surgery vs. Intensity Modulated Radiotherapy for Stage I Nasopharyngeal Carcinoma.

The goal of this clinical trial is to compare the survival and adverse reactions differences between endoscopic surgery and intensity modulated radiotherapy for patients with newly diagnosed stage Ⅰ nasopharyngeal carcinoma, aiming to verifying the efficacy and safety of endoscopic surgery for stage Ⅰ nasopharyngeal carcinoma.

18 - 75 years of age All Phase N/A

Safety and Efficacy of Enhanced Recovery After Surgery in Neurocritical Care

Enhanced recovery after surgery (ERAS) is a strategy of perioperative management aimed to accelerate the rehabilitation of patients through various optimized perioperative managements as well as ongoing adherence to a patient-focused, multidisciplinary, and multimodal approach. Alleviating the injury and stress caused by surgery or disease is the core principle of …

18 - 75 years of age All Phase N/A
S Sena Battal

The Effect of Ney Music on Patients Undergoing Lumbar Disc Surgery

This randomized controlled study aims to investigate the effects of ney music listening, a traditional Turkish wind instrument, on pain, anxiety, sleep quality, and vital signs in patients undergoing lumbar disc herniation surgery. Participants will be randomly assigned to intervention and control groups. The intervention group will receive a 15-minute …

18 - 70 years of age All Phase N/A
A Ana Maria Dumitriu, MD, PhD

Remimazolam vs. Midazolam for Sedation and Cognitive Outcomes in Orthopedic Surgery

This study aims to compare two medications, Remimazolam and Midazolam, used for sedation during orthopedic surgeries performed under regional anesthesia. We want to find out which medication provides better sedation during the procedure and which one affects early recovery of brain function after surgery. Older adults (65 years and above) …

65 years of age All Phase 3

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