Advanced Filters
noise

Surgery Clinical Trials

A listing of Surgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,630 clinical trials
A Antti Nykänen, Docent

Atrial Appendage Micrograft Transplants to Assist Heart Repair After Cardiac Surgery

Ischemic heart disease (IHD) leads the global mortality statistics. Atherosclerotic plaques in coronary arteries hallmark IHD, drive hypoxia, and may rupture to result in myocardial infarction (MI) and death of contractile cardiac muscle, which is eventually replaced by a scar. Depending on the extent of the damage, dysbalanced cardiac workload …

18 - 75 years of age All Phase N/A
S Sevim Sen, PhD

The Effect of Virtual Reality on Preoperative Anxiety Before Abdominal Surgery

Hospitalization, medical interventions to be performed, and uncertainties specific to surgical intervention create a certain level of anxiety in the patient. It is known that being in the hospital negatively affects the coping mechanisms of the patient. In the pre-surgical period, the nurse's practices that will facilitate the patient's coping …

18 - 70 years of age All Phase N/A
G Grace Lander

SRG-514 Administered Intraoperatively to Patients Undergoing Breast-conserving Cancer Surgery

This is a multicenter, first-in-human (FIH), open label, Phase 1 dose escalation and recommended Phase 2 dose (RP2D) extension trial with a primary objective to define the RP2D of SRG-514 when administered intraoperatively to patients undergoing breast-conserving cancer surgery. SRG-514 will be investigated utilizing a 3+3 convention dose escalation cohorts.

18 years of age All Phase 1
D Doaa Ali Gamal

Processed Electroencephalography-guided General Anesthesia and Outcomes in Major Abdominal Surgery

This study aims to evaluate whether the reduction in the amount of intraoperative norepinephrine required to prevent hypotension, facilitated by processed electroencephalography (pEEG) -guided general anesthesia, will lead to a decrease in postoperative complications, particularly acute kidney injury (AKI).

18 - 70 years of age All Phase N/A
K Kenneth Cardona, MD

Function of Tamsulosin in Older Males Undergoing Surgery with Indwelling Catheter

This study is being done to answer the question: What is the impact of a medication called tamsulosin (also called Flomax) on the rate of postoperative urinary retention (POUR) and catheter-associated urinary tract infection (UTI)? One of the most common complications following surgery and associated with Foley catheters is post-operative …

50 years of age Male Phase 3
G Ghulam Murtaza, MBBS, FCPS, MRCS, MSc (epi)

Role of Tranexamic Acid in Reducing Hemorrhagic Events in Bariatric Surgery

The goal of this clinical trial is to learn if tranexamic acid (TXA) helps reduce bleeding during bariatric surgery, such as laparoscopic sleeve gastrectomy (LSG) and mini gastric bypass (MGB). It will also look at how safe TXA is for people undergoing these procedures. The main questions it aims to …

18 - 60 years of age All Phase 4
H Hongwei Zhu, doctorate

Application of Augmented Reality Neuronavigation in Transnasal Endoscopic Skull Base Surgery

"For lesions in the skull base, including meningiomas, chordomas and pituitary tumors, endoscopic surgery has replaced traditional microscopes as the mainstream procedure. Although neurosurgeons can enlarge the surgical area using a neuroendoscope, it does not provide any information on the morphology and location of anatomical structures beneath visible surfaces. Due …

years of age All Phase N/A
J Jiangling Wang, Dr.

Postoperative Analgesia Between Paravertebral Block and Epidural Block in Esophageal Surgery

Prevention of postoperative pain is essential for the recovery of esophageal surgery. Epidural analgesia is a traditional and standard perioperative pain management for these patients. Beneficials of epidural analgesia have been widely established. However, there are still several potential disadvantages such as perioperative hypotension, failure of administration, rare but serious …

18 - 80 years of age All Phase N/A
S Serkan Tulgar

Interscalene Vs Infraspinatus-teres Minor (ITM) Interfascial Block in Shoulder Surgery

Postoperative pain is important following arthroscopic shoulder surgery. Postoperative effective pain treatment provides early mobilization and shorter hospital stay.Ultrasound (US)-guided brachial plexus blocks such as interscalen and supraclavicular block are usually performed. Interscalene brachial plexus block is one of the most preferred techniques among these. Due to the phrenic nerve …

18 - 75 years of age All Phase N/A
P Peter-Martin Krarup, Associate Professor

Low Versus Standard Intraabdominal Pressure in Robot-assisted Colorectal Cancer Surgery

The goal of this clinical trial is to investigate the influence of low intraabdominal pressure (compared to standard intraabdominal pressure) during robot-assisted colorectal cancer surgery on patients wellbeing after surgery. Patients included are diagnosed with colon- or rectal cancer, and scheduled for curatively intended surgery. The main question the trial …

18 years of age All Phase N/A

Simplify language using AI