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Surgery Clinical Trials

A listing of Surgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,628 clinical trials
N Nicolas GOLSE, phD

Hepatic and Systemic Hemodynamic Modeling During Liver Surgery

" Despite the medical and surgical progress of the last two decades, the selection of candidates for liver surgery remains based on old principles and insufficiently sensitive to fine-tune the gesture to patient-specific characteristics and make almost zero risks of postoperative liver failure (PLF) and death. It is therefore necessary …

18 years of age All Phase N/A
S Stacee Baker, MEd, BSN, RN

Skin Preparation for Elective Foot and Ankle Surgery

Surgical site infections (SSIs) make about 31% of all nosocomial infections and they are the most common hospital-acquired infection. For foot and ankle elective interventions, SSI rate is reported between 0.4% and 3.6%. This study will investigate the effectiveness of skin cleaning with isopropyl alcohol and scrubbing with chlorhexidine soap …

18 years of age All Phase 4

Who Will Benefit From Bariatric Surgery for Diabetes?

A study investigating the influence of fat distribution, genetic susceptibility markers for type 2 diabetes (T2DM) and fat distribution, epigenetic and transcriptomic changes and gut hormone responses to a mixed meal on diabetes remission following bariatric surgery.

18 - 80 years of age All Phase N/A
F For more information at the NIH Clinical Center contact Office of Patient Recruitment (OPR)

Surgery as a Treatment for Medically Intractable Epilepsy

Background \- Drug resistant epilepsy is the term used to describe epilepsy that cannot be controlled by medication. Many people whose seizures do not respond to medication will respond to surgical treatment, relieving seizures completely or almost completely in one-half to two-thirds of patients who qualify for surgery. The tests …

8 - 99 years of age All Phase N/A
H Hipolito Labandeyra Gonzalez, Anesthesiologist

Modulation of the Inflammatory Response in Bariatric Surgery

This study will evaluate how different anesthesia techniques affect inflammation after bariatric surgery. Patients will be randomly assigned to receive one of three approaches: opioid-free anesthesia, intravenous anesthesia with opioids, or inhalational anesthesia with opioids. The study will measure blood levels of inflammation-related substances (such as IL-6, CRP, cortisol, ESR …

18 - 65 years of age All Phase N/A

Enhanced Recovery After Surgery (ERAS) for Complicated Appendicitis

The exploratory objective of this pilot study is to evaluate the feasibility and safety of an enhanced recovery protocol that will allow adult patients to be discharged to home on an oral antibiotic regimen for three days following a laparoscopic appendectomy for complicated appendicitis. Feasibility will be determined by high …

18 years of age All Phase N/A
C Christina P Madsen, MD

Transverse Versus Longitudinal Groin Incision in Vascular Surgery

The purpose of the study is to examine whether incision type has an influence on the development of groin wound complications after operation in the groin in vascular surgery. The main questions it aims to answer are: Does a transverse incision in the groin lead to fewer surgical site complications …

years of age All Phase N/A
W Wan-guang Zhang, M.D.

Precision Adjuvant Therapy After Surgery for Hepatocellular Carcinoma

Vessels that encapsulate tumor clusters (VETC) is an invasive metastatic factor in HCC independent of the epithelial mesenchyme transition (EMT), and VETC-positive patients have a higher rate of postoperative recurrence. How to improve the prognosis of this group of patients is an urgent issue to be addressed.

18 - 75 years of age All Phase 4

Three Types of Papilla Incision in Periodontal Surgery

Three types of papilla incision in periodontal reconstruction techniques will be compared.

18 - 80 years of age All Phase N/A
A Abdul El-Rabbany, DMD

Antibiotics for Prevention of Infection Following Orthognathic Surgery

Orthognathic surgery describes a group of procedures aimed at correcting developmental or acquired deformities of the jaws and facial skeleton. The goal of these procedures is to improve speech, jaw and dental function, aesthetics, and symptoms of sleep apnea. This is accomplished by surgical repositioning of the upper jaw (maxilla) …

16 years of age All Phase 4

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