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Surgery Clinical Trials

A listing of Surgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,628 clinical trials
Z Zhi Zheng, Attending surgon

Digital Rehabilitation for Gastric Cancer Surgery After Neoadjuvant Therapy

The goal of this clinical trial is to investigate the effects of a perioperative multimodal rehabilitation program on the incidence of postoperative complications and perioperative clinical indexes including functional capacity, nutritional and psychological status in patients with gastric cancer undergoing neoadjuvant therapy. Besides the investigators also develop a smart phone …

18 - 70 years of age All Phase N/A
a arif timuroglu

Mechanical Power During Different Ventilation Modes in Laparoscopic Surgery

This study investigates how different breathing machine (ventilator) settings affect the energy delivered to the lungs during surgery. Mechanical power is a measure of this energy, and high levels can sometimes lead to lung irritation. In clinical practice, a mode called Pressure-Regulated Volume Control (PRVC) is often used because it …

18 years of age All Phase N/A
M Murat Rıfat Research Assistan, DDS

Changes in Depression and Esthetic Perception After Orthognathic Surgery

This study aims to evaluate changes in depressive symptoms and subjective esthetic perception before and after bimaxillary orthognathic surgery in patients with different types of malocclusion. The study will analyze anonymized clinical data and questionnaire responses to assess the impact of orthognathic surgery on psychological well-being and esthetic perception.

18 - 40 years of age All Phase N/A
N Nieves Pérez, cirugía

Longitudinal Study of the Psychological Impact of Bariatric Surgery

This prospective observational study evaluates the effect of bariatric surgery on mental health and hair cortisol in patients with morbid obesity over a 3-year follow-up. Assessments will be performed before surgery and at 1 month, 1 year, 2 years, and 3 years to analyze psychological changes, weight changes, and the …

18 - 70 years of age All Phase N/A
S Salvatore Notaro, MD

NIRS MONITORING OF SPINAL CORD ISCHEMIA IN AORTIC SURGERY

This prospective observational study aims to evaluate the feasibility and clinical utility of near-infrared spectroscopy (NIRS) monitoring applied to paraspinal muscles as a surrogate marker of spinal cord perfusion in patients undergoing major noncardiac surgery. Spinal cord ischemia represents a rare but devastating complication, often difficult to detect in real …

18 years of age All Phase N/A
Y Yishan Huang, Ph.D

Bariatric Surgery Combined With GLP-1 Receptor Agonists Study

Obese patients exhibit considerable heterogeneity and complex comorbidities, making long-term effective management challenging with single therapies. While bariatric surgery remains the most effective weight-loss intervention, postoperative weight regain and metabolic deterioration require attention. GLP-1 RAs offer distinct advantages for weight and metabolic improvement, and their combined application with surgery may …

18 - 60 years of age All Phase 1/2
M Musa Zengin, MD

Flow-Controlled Versus Volume-Controlled Ventilation in Bariatric Surgery

This prospective trial aims to compare the effects of flow-controlled ventilation (FCV) and volume-controlled ventilation (VCV) on intraoperative airway pressures and oxygenation in bariatric surgery under general anesthesia. Obesity is associated with altered respiratory mechanics, reduced functional residual capacity, and increased airway pressures, making the selection of an optimal ventilation …

18 - 65 years of age All Phase N/A
M Mohammed H Ali, MD

Using Retrograde Intrarenal Surgery for Managing Staghorn Renal Stones.

This prospective, randomized study is comparing the safety and efficacy of using two types of ureteral access sheaths in managing staghorn renal stones by retrograde intrarenal surgery.

18 - 70 years of age All Phase N/A

CTR-FAPI-guided Precision Surgery for Newly Diagnosed MTC

This is a multicenter, randomized, open-label, non-inferiority Phase III clinical trial, aims to compare 68Ga-CTR-FAPI PET-CT-guided surgery to investigator-chosen surgical approaches to evaluate its efficacy in treating newly diagnosed medullary thyroid carcinoma. This study plans to enroll 150 newly diagnosed MTC patients, who will be randomly assigned in a 2:1 …

years of age All Phase 3
B Barbara Sinner, MD, PhD

Preoperative Optimization Before Total Hip or Knee Replacement Surgery

Preoperative Optimisation prior to Hip and Knee Arthroplasty (PrOpE) Many patients scheduled for planned hip or knee replacement surgery have health conditions that may affect recovery, such as reduced physical fitness, nutritional problems, multiple medications, or increased stress and anxiety. These factors can increase the risk of complications and delay …

18 - 99 years of age All Phase N/A

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