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Surgery Clinical Trials

A listing of Surgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,670 clinical trials

Intrathecal Morphine Versus Epidural Analgesia for Open Colon Surgery

Effective pain management after abdominal surgery is essential for recovery. This study compares two pain relief methods-intrathecal morphine (a single spinal injection) and continuous epidural analgesia-for patients undergoing open colorectal cancer surgery. The investigators expect intrathecal morphine to provide equal pain relief at rest 24 hours after surgery, while epidural …

18 - 80 years of age All Phase 4

Effect of Adult Spinal Deformity Surgery on Functional Reach

Adult spinal deformity (ASD) is a common spinal condition that often impacts an individual's ability to stand and maintain an upright posture. Poor balance often limits an individual's ability to perform basic activities of daily life (ADL) and can lead to disability. Current considerations of correcting ASD to improve balance …

18 years of age All Phase N/A
A Alexander T Yahanda, MD, MPHS

Trans-Auricular Stimulation for Postoperative Inflammation in Spine Surgery

This study is a randomized controlled trial that will evaluate the effect of non-invasive auricular vagal nerve stimulation on inflammatory markers, glycemic control, postoperative pain, and inflammation-related clinical outcomes after long-segment spinal fusion surgeries when compared to current accepted management.

18 years of age All Phase N/A
A Amy Monroe

Personalized Postoperative Pain Management Following Thoracic Surgery in Adults

The proposed research is an important extension of an ongoing perioperative personalized analgesia and intravenous opioid pharmacogenetic research. This research focuses on two of the most commonly used oral opioid analgesics, oxycodone, and methadone, in adults following thoracic surgery. Major inpatient thoracic surgeries (TS) for lung disease are common and …

18 - 99 years of age All Phase N/A
B Byung Soh Min

Ultrasonic Versus Conventional Clipping Hemostasis in Laparoscopic Colorectal Surgery

INTRODUCTION Colorectal cancer rates are rising, with surgery emphasizing radical resection and vessel ligation. Conventional methods using clips pose risks of bleeding and complications. Ultrasonic scalpels offer a safer alternative, approved for various surgeries, but their efficacy in colorectal cancer surgery needs prospective validation. STUDY OBJECTIVE Study compares safety/efficacy of …

19 - 80 years of age All Phase N/A
B Benedetta Guani BG HFR Fribourg - Hôpital cantonal

Confocal Histolog Scanner in Routine Breast-Conserving Surgery (CHiB)

The clinical performance study is collecting data from the use of a CE mark product used within the scope of its intended purpose to intraoperatively visualize tissue specimen. The subjects are not submitted to invasive and burdensome procedures compared to the standard of care surgical practices and regular use of …

18 years of age Female Phase N/A

Automated Intraoperative Lung Recruitment Maneuvers in Major Laparoscopic Surgery

Laparoscopic colorectal surgery is associated with an increased risk of intraoperative atelectasis due to pneumoperitoneum, Trendelenburg positioning, and prolonged anesthesia duration. Atelectasis developing during surgery may persist into the postoperative period and contribute to postoperative pulmonary complications. Automated lung recruitment maneuvers delivered by modern anesthesia ventilators may offer a standardized …

18 - 80 years of age All Phase N/A

Impact of Sleep Quality on Outcomes After Cardiac Surgery

Sleep is a basic human need and is essential for good quality of life, good health. In fact, humans spend one third of their life time in sleeping or attempting to do so. However, sleep is not given due importance in intensive care unit (ICU)'s, although it is critical in …

18 - 80 years of age All Phase N/A
M Michael Achiam, MD, DMSCi

FLuorescence Guided Assessment of Mesenteric Ischemia in Emergency Surgery

This is a prospective, multicentre, non-randomized cohort study using real-time intraoperative visualization of bowel perfusion by indocyanine green (ICG) in all-cause bowel ischemia. At intraoperative finding of bowel ischemia, the initial intraoperative plan is noted and resection margins marked with a steril pen. A fluorescence angiography will be performed and …

18 years of age All Phase N/A

A Study of Bevonescein in Patients Undergoing Abdominopelvic Surgery

Feasibility study of Bevonescein to highlight Nerves and Ureter in patients undergoing Minimally Invasive Surgery

18 years of age All Phase 2

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