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Surgery Clinical Trials

A listing of Surgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,670 clinical trials
G Guillaume Martel, MD

Hemoglobin Levels for Blood Transfusions During and After Surgery

The goal of this pilot clinical trial is to learn if it is achievable to conduct a large-scale clinical trial whereby, the investigators will compare two ways of deciding when to give a blood transfusion during surgery. Participants in this study are adults undergoing surgery with a risk of significant …

18 years of age All Phase N/A
L Laine Abernathy

Apixaban or Enoxaparin After Head and Neck Cancer Surgery

The goal of this clinical trial is to learn if apixaban (a pill) is a safe and easier alternative to taking enoxaparin (a daily shot) to prevent blood clots after head and neck cancer surgery. It will also learn about side effects of both medicines. The main questions it aims …

18 - 89 years of age All Phase 4

Intravenous Methadone for Sternotomy Pain Control in Cardiac Surgery

Background Postoperative pain is significant in cardiac surgical patients. Perioperative analgesia with intermittent administration of opioids can result in significant fluctuations in serum opioid concentrations. Methadone should provide a rapid onset and long-term pain relief upon a single intravenous dose at induction of anaesthesia, and may reduce chronic postsurgical pain …

18 years of age All Phase 3
C Calvin Sze Hang Ng

Thoracic Surgery by the Medtronic Hugo™ Robotic System

The introduction of robot-assisted surgery is one of the biggest breakthroughs in surgery, and represents the most significant advancement in minimally invasive surgery of recent decades. One of the first surgical uses of the robot was in orthopaedics, neurosurgery and cardiac surgery. However, it's use has now been well recognized …

18 - 80 years of age All Phase N/A

Ketamine for Preventing Post-Spinal Hypotension in Orthopedic Surgery

This randomized, double-blind, controlled clinical trial investigates the efficacy of a sub-anesthetic dose of ketamine (0.5 mg/kg IV) in preventing post-spinal hypotension in patients undergoing elective orthopedic surgeries under spinal anesthesia. The study compares ketamine with placebo (normal saline) in terms of blood pressure stability and incidence of hypotensive episodes …

18 years of age All Phase N/A
E Ehab Farag, MD

EOIFP Block Versus OSTAP Block for Upper Abdominal Surgery

The investigators propose a single-center, assessor blinded, randomized control trial to compare the efficacy of external oblique fascial plane (EOIFP) block versus Oblique Subcostal Transversus Abdominis Plane (OSTAP) block for patients undergoing open upper abdominal surgery at Cleveland Clinic Main Campus.

18 years of age All Phase N/A

Intraoperative Hypotension and Metabolomics in Major Upper Gastrointestinal Surgery

We will investigate the effect of hypotension prediction index guidance on intraoperative hypotension and metabolomics in patients undergoing major upper gastrointestinal surgery

20 - 80 years of age All Phase N/A
z zhang ying, Master degree

Clinical Study of Perioperative Sleep Disorders in Cardiac Surgery

The aim of this clinical trial is to understand the effects of dexmedetomidine and esketamine on postoperative sleep in patients undergoing cardiac surgery. The main questions it aims to answer are: Does dexmedetomidine or esketamine prevent the development of postoperative sleep disturbances? Which one works better? The researchers compared dexmedetomidine …

40 - 75 years of age All Phase 4
H Huanlei Huang Phd

Surgical Treatments of Tricuspid Valve Regurgitation After Cardiac Surgery

This study aims to present our center's experience in managing postoperative tricuspid valve regurgitation over the past 25years and to analyze the outcomes of these surgical treatments.

16 years of age All Phase N/A
S Shymaa Y Abo zaid

Phase One Cardiac Rehabilitation Outcomes Post Valve Replacement Surgery

Cardiac rehabilitation is a crucial component of postoperative recovery for patients who have received valve replacement surgery. Aim: This study aimed to evaluate the effectiveness of phase one cardiac rehabilitation in improving cardiovascular function, pulmonary capacity, functional ability, and quality of life.

40 - 55 years of age All Phase N/A

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