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pain Clinical Trials

A listing of pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,757 clinical trials
M Maha Nasr, Assistant professor

The Effect of Three Different Medications on Anesthetic Success and Postoperative Pain

Pain is a very important factor in Endodontic treatment, Both intra- and Post-operatively. In case of symptomatic Irreversible pulpitis, a build up of inflammatory mediators makes it very difficult for the operator to reach the desired level of anesthesia in order to deliver a pain free treatment as well as …

18 years of age All Phase N/A
F Frauke Musial, Ph.d.

Vacuum Massage vs Tactile Massage for the Treatment of Chronic Neck Pain

Chronic pain significantly impacts individuals and society, with about 30% of Norwegian adults affected, making it the leading cause of long-term sick leave and disability benefits. Concerns over addiction to pain medications highlight the need for non-pharmacological treatments, though many such therapies, often complementary or alternative, are not widely available …

21 - 75 years of age All Phase N/A
B Beni-Suef

KT vs IASTM on Upper Trapezius Myofascial Trigger Points To Compare Effect of KT VS IASTM on Pain Intensity, Pain Pressure Threshold, Cervical Range of Motion and Functional Disability Level.

This study would answer the following question: Is there a difference in the effects between IASTM and KT on pain intensity level, pain pressure threshold, cervical range of motion (ROM), functional disability level and satisfaction level in subjects with upper trapezius myofascial trigger points? The aims of this study are: …

19 - 23 years of age All Phase N/A
I Irene Bachero, MD

Pain and Quality of Life After Inguinal Hernia Repair: Laparoscopic Versus Open Repair.

This investigation will be a double-armed, randomized prospective study designed to compare open (Lichtenstein Technique) versus laparoscopic (TAPP) repair of primary unilateral inguinal hernia. Chronic pain, restriction of activities and esthetical outcome will be evaluated preoperatively and postoperatively, at 1, 4 and 12 months, using the European Registry for Abdominal …

18 - 85 years of age All Phase N/A
T Timothy Johnson, MD

Sustained Acoustic Medicine (SAM) for Symptomatic Treatment of Pain Related to Bone Fracture

The purpose of this study is to assess the ability of long-duration low-intensity therapeutic ultrasound (LITUS) to alleviate bone-fracture related pain over a 12-week period. The primary objective of this study is to evaluate the analgesic effect of LITUS in subjects suffering from bone-fracture pain. Secondary objectives are to assess …

18 - 80 years of age All Phase 1
D Deborah M Delevan, MEd

Group-Based Psychological Treatments Over Video Conference for Older Veterans With Chronic Pain

This study is being performed to compare the effects of three types of group-based psychological treatments delivered over video telehealth for chronic musculoskeletal pain in older U.S. military Veterans. The three types of psychological treatments are: Cognitive-Behavioral Therapy (CBT), Emotional Awareness and Expression Therapy (EAET), and Mindfulness Meditation (MM). In …

60 - 95 years of age All Phase N/A
M Marc K Olsen, MD

Perineural Injections of Incobotulinumtoxin-A for Diabetic Neuropathic Pain of the Lower Extremities

The goal of this clinical trial is to test perineural injections (injections around a nerve) of incobotulinumtoxin-A in participants with diabetic nerve pain of the feet and lower legs. The main questions it aims to answer are: Is the treatment safe and effective? Does the treatment affect participants quality of …

18 years of age All Phase 2
P PARICHAY SINGHAL, PG STUDENT

Effect of Cavity Disinfectants on Post Operative Pain & Success of Partial Caries Removal

To investigate The Effect of Sodium hypochlorite and Chlorhexidine as cavity Disinfectants on the post operative pain and Success of Partial Caries Removal in deep carious lesion with moderate pulpitis in permanent teeth

18 years of age All Phase N/A
M Mohamed ElMeligie, Ph.D

Mechanical Modalities vs. Standard Care for Edema and Pain Management After DRF Fixation

This single-blinded, randomized controlled trial (RCT) will evaluate the added benefit of mechanical modalities (continuous passive motion (CPM) and intermittent pneumatic compression (IPC)) when integrated into standard therapy for managing postoperative edema and pain in patients undergoing distal radius fracture (DRF) fixation. The primary outcomes are edema volume (measured via …

18 - 65 years of age All Phase N/A

Transcranial Direct Current Stimulation on Functionality and Pain in Individuals with Patellar Tendinopathy

The aim of the present study is to investigate the effectiveness of transcranial direct current stimulation (tDCS) prior to a therapeutic eccentric exercise program on parameters related to pain and functionality in individuals with patellar tendinopathy. For this purpose, participants will be randomly divided into two groups: i) experimental group, …

18 - 50 years of age All Phase N/A

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