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pain Clinical Trials

A listing of pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,757 clinical trials

The Effect of Exposure to Aversive Non-verbal Vocalizations on Pain Tolerance

Humans produce non-verbal vocalizations (shouting, growling, screaming), laughter, ...) in various contexts that are likely to perform biological functions. and important social issues. Yet despite their importance in the human vocal repertoire, the mechanisms and functions of non-verbal vocalizations remain little studied and poorly understood including in humans. In this …

18 - 60 years of age All Phase N/A
H He Cai, Phd

Effects of Aromatherapy on Anxiety and Pain During Dental Treatment in Adults

Dental anxiety is a common problem in dental care. The aim of this protocol is to evaluate the effect of orange and tea essential oil for the control of anxiety and pain in adults during dental treatments.

18 - 40 years of age All Phase N/A

Impact of Gel Aromatherapy on Pain for Patients With De Quervain Disease

De Quervain disease is characterized by an adductor pollicis longus and extensor pollicis brevis tendons inflammation as thys pass beneath the extensor retinaculum at the radial styloid. This pathology is recognized as a musculoskeletal disorder of the upper limb triggering functional deficits resulting to possible modifications in the professional activity, …

18 - 75 years of age All Phase 4
S Serdar Kılınç

Comparison of Efficiency of Interferential Current Application Methods in Chronic Neck Pain

The aim of this study is to evaluate the effects of Interferential Current Therapy on pain, disability, and quality of life in patients with chronic neck pain and to compare the effects of applying Interferential Current Therapy with vacuum electrodes versus carbon-silicon pad electrodes.

20 - 50 years of age All Phase N/A
E Emma Ramsay Milford, DEdPsy

Digital Psychological Intervention for Pediatric Functional Abdominal Pain Disorders in Primary Care

The project involves researching two psychological treatments for functional abdominal pain in children. The treatments will be offered to children as an early intervention, at primary care level. The study will aim to find out if the treatments are effective and which children the different treatments are effective for.

8 - 14 years of age All Phase N/A
S Severin Vogt, Dr. med.

Acute Analgesic Effects of DMT on Experimentally Induced Pain in Healthy Participants

N,N-dimethyltryptamine (DMT) is a classical psychedelic with similar effects like LSD or psilocybin. Preliminary evidence from case series and small open-label trials suggests that psychedelics may be promising candidates for the treatment of several pain-related diseases such as chronic pain, migraine, cluster headache or phantom limb pain. However, data from …

25 - 75 years of age All Phase 1
W Weihua Zhao, Phd

The Power of Belief: Expectation-driven and Placebo Modulation of Empathic Pain

This study investigates how belief and expectation influence empathic pain-the pain we feel when observing others in distress. Healthy adult participants will be randomly assigned to one of three groups: no-treatment control, placebo nasal spray, oxytocin-containing nasal spray. Participants in both the placebo and oxytocin conditions will be informed that …

18 - 30 years of age All Phase N/A

Correlation Between Postoperative Pain and Apical Extrusion of Different Irrigation Activation Techniques

The aim of this clinical trial is : To evaluate effect of different techniques of irrigant activation: LASER activation sonic activation ultrasonic activation passive needle irrigation On Postoperative pain in vital teeth (Randomized controlled trial) Amount of apical extrusion (In vitro study) Participants will describe their preoperative pain and postoperative …

18 - 50 years of age All Phase N/A
A Afaf Mohamed Omar Tahoon, PhD/ Lecturer

Effect of Upper Thoracic Manipulation on Neck Pain and Selected Muscle Activities

This study will investigate the immediate and short-term effects of upper thoracic manipulation versus sham upper thoracic manipulation on Pain intensity, Cervical ROM, the myoelectric activity of the sternocleidomastoid muscle and upper trapezius muscle during Maximum voluntary isometric contraction.

18 - 40 years of age All Phase N/A
S Sara L. Peterson, PhD

Detecting Change in Muscle Parameters, Pain, and Function with NMES for TTA

The proposal aims to investigate a non-invasive, cost-effective method for rebuilding muscle mass in individuals with transtibial limb loss. Maintaining a healthy, pain-free residual limb is a primary concern for prosthesis users. Amputees commonly experience muscle deficits leading to mobility issues, poor prosthetic fit, and chronic pain. Neuromuscular electrical stimulation …

18 - 100 years of age All Phase N/A

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