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Essential Tremor Clinical Trials

A listing of Essential Tremor medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 48 clinical trials
L Leila Harwood

Evaluating the Impact of Virtual Reality on Mood in Patients Undergoing Magnetic Resonance-Guided Focused Ultrasound for Medication-Refractory Essential Tremor

The primary objective of this randomized study is to evaluate the effect of a virtual reality (VR) video on pre-treatment anxiety levels in individuals undergoing magnetic resonance-guided focused ultrasound (MRgFUS) treatment for medication-refractory essential tremor (ET). Participants will be randomized to view one of two VR videos, and pre-treatment anxiety …

18 years of age All Phase N/A
K Kristina Simonyan, MD, PhD

Clinical Validation of DystoniaNet Deep Learning Platform for Diagnosis of Isolated Dystonia

This research involves retrospective and prospective studies for clinical validation of a DystoniaNet deep learning platform for the diagnosis of isolated dystonia.

years of age All Phase N/A
E Edouard COURTIN, Dr

Electroclinical Correlates in Essential Tremor

Essential tremor (ET) is a neurological disorder that affects nearly 0.9% of the world's population. High-frequency Deep Brain Stimulation (DBS) of the ventral-intermediate nuclei of the thalamus (VIM) has been proven as an effective second-line treatment for severe forms of ET. The arrival on the market of the PERCEPT™ (new …

18 - 75 years of age All Phase N/A
L Liankun Ren, MD

Temporal Interference for Essential Tremor

This single-center prospective study aims to investigate the treatment efficacy of temporal interference (TI) in essential tremor patients aged 30-70.

30 - 70 years of age All Phase N/A
L Leo P. Sugrue, MD PhD

Ultrasound Neuromodulation in Essential Tremor

This study is being done to test whether low-intensity focused ultrasound (LIFU) (low energy sound waves) cause temporary changes in brain activity and behavior when directed at particular parts of the brain. By targeting LIFU to the parts of the brain thought to be responsible for essential tremor (ET), and …

18 years of age All Phase N/A
J Julia C Gonzalez, BA

Circadian Adaptive DBS in Essential Tremor

Deep brain stimulation (DBS) of the thalamus is an effective treatment for medically refractory essential tremor (ET). DBS involves delivering continuous stimulation to the brain through electrodes permanently implanted in the thalamus. Despite proven effectiveness, the long-term benefit of DBS can wane over time (habituation) and side effects, including paresthesia …

21 - 89 years of age All Phase N/A

The Swedish Essential Tremor (SWEET) Trial

To evaluate the effect of deep brain stimulation (DBS) vs best medical treatment in essential tremor (ET) in a randomized, single-blinded controlled trial.

18 - 75 years of age All Phase N/A
C Christian Iorio-Morin, MD, PhD

Bilateral Essential Tremor Treatment With Gamma Knife

Combined Phase II/III, multi-center, prospective, single-blinded trial. Ten (10) patients with essential tremor who previously underwent successful and uncomplicated GK thalamotomy for essential tremor will undergo a contralateral treatment. The incidence of side effects will be determined at 3 months postoperatively, graded per the CTCAE v5 and analyzed by a …

18 years of age All Phase 2/3
P Peter M Grund, BS

Coordinated Reset Deep Brain Stimulation for Essential Tremor

Deep brain stimulation (DBS) is a surgical procedure for the treatment of Essential Tremor (ET). A novel approach to current DBS approaches is called coordinated reset DBS (CR-DBS) which uses different patterns of stimulation at lower currents and can address the limitations of traditional DBS that uses continuous high amplitude, …

21 years of age All Phase 1

Repetitive Transcranial Magnetic Stimulation Therapy in Essential Tremor

The purpose of this study is to evaluate the efficacy and electrophysiology of repetitive transcranial magnetic stimulation in the treatment of essential tremor.

18 - 80 years of age All Phase N/A

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