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Essential Tremor Clinical Trials

A listing of Essential Tremor medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 52 clinical trials
L Liankun Ren, MD

Temporal Interference for Essential Tremor

This single-center prospective study aims to investigate the treatment efficacy of temporal interference (TI) in essential tremor patients aged 30-70.

30 - 70 years of age All Phase N/A
L Leo P. Sugrue, MD PhD

Ultrasound Neuromodulation in Essential Tremor

This study is being done to test whether low-intensity focused ultrasound (LIFU) (low energy sound waves) cause temporary changes in brain activity and behavior when directed at particular parts of the brain. By targeting LIFU to the parts of the brain thought to be responsible for essential tremor (ET), and …

18 years of age All Phase N/A
J Julia C Gonzalez, BA

Circadian Adaptive DBS in Essential Tremor

Deep brain stimulation (DBS) of the thalamus is an effective treatment for medically refractory essential tremor (ET). DBS involves delivering continuous stimulation to the brain through electrodes permanently implanted in the thalamus. Despite proven effectiveness, the long-term benefit of DBS can wane over time (habituation) and side effects, including paresthesia …

21 - 89 years of age All Phase N/A

The Swedish Essential Tremor (SWEET) Trial

To evaluate the effect of deep brain stimulation (DBS) vs best medical treatment in essential tremor (ET) in a randomized, single-blinded controlled trial.

18 - 75 years of age All Phase N/A
C Christian Iorio-Morin, MD, PhD

Bilateral Essential Tremor Treatment With Gamma Knife

Combined Phase II/III, multi-center, prospective, single-blinded trial. Ten (10) patients with essential tremor who previously underwent successful and uncomplicated GK thalamotomy for essential tremor will undergo a contralateral treatment. The incidence of side effects will be determined at 3 months postoperatively, graded per the CTCAE v5 and analyzed by a …

18 years of age All Phase 2/3

Repetitive Transcranial Magnetic Stimulation Therapy in Essential Tremor

The purpose of this study is to evaluate the efficacy and electrophysiology of repetitive transcranial magnetic stimulation in the treatment of essential tremor.

18 - 80 years of age All Phase N/A
M Mary Ann Barnett

3-D Tractography FUS Ablation for Essential Tremor

The investigators propose to advance Vim-FUSA (Ventral Intermediate Nucleus - Focused Ultrasound Ablation) with the support of 3-D tractography, a neuroimaging technique to visually represent nerve tracts within the brain. The investigators hypothesize that 3-D tractography Vim-FUSA will improve the Vim ablation compared to standard Vim-FUSA and prove safe and …

22 years of age All Phase N/A
P Peter M Grund, BS

Coordinated Reset Deep Brain Stimulation for Essential Tremor

Deep brain stimulation (DBS) is a surgical procedure for the treatment of Essential Tremor (ET). A novel approach to current DBS approaches is called coordinated reset DBS (CR-DBS) which uses different patterns of stimulation at lower currents and can address the limitations of traditional DBS that uses continuous high amplitude, …

21 years of age All Phase 1
A Aleksandra Napieralska, MD, PhD

Stereotactic Radiosurgery in the Treatment of Essential Tremor

The goal of this interventional study is to evaluate the effectiveness of treatment using stereotactic radiosurgery in the treatment of essential tremor in adult patients

50 years of age All Phase 2
S Shiro Horisawa, MD

Simultaneous Bilateral Radiofrequency Thalamotomy for Medication-Refractory Essential Tremor

This study aims to evaluate the safety and effectiveness of simultaneous bilateral radiofrequency thalamotomy for patients with medication-refractory essential tremor (ET). Essential tremor is a common neurological condition that causes involuntary shaking, often affecting the hands and interfering with daily activities such as writing, eating, or using tools. While medications …

20 - 70 years of age All Phase N/A

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