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Intermittent Explosive Disorder Clinical Trials

A listing of Intermittent Explosive Disorder medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 60 clinical trials
J Jing Wang

Optimization of Minocycline for Helicobacter Pylori Rescue Treatment

The efficacy of bismuth-containing quadruple therapy with minocycline and metronidazole was not inferior to classical bismuth quadruple therapy for refractory H. pylori infection, though also accompanied with high occurrence of adverse events (55.4%). Optimization of minocycline-based regimen to achieve high eradication rate with fewer adverse events is imperative. This study …

18 - 80 years of age All Phase 4
H Haiming Zhang

High-dose Dual Therapy and Minocycline-cotaining Quadruple Therapy for Helicobacter Pylori Infection

This study is a multicentra, prospective study. The enrolled patients are HP positive. They are diagnosed as HP positive by rapid urease test and/or 13C urea breath test. According to the declaration of Helsinki, 200 patients will be included in this study. After obtaining the written informed consent of the …

18 - 70 years of age All Phase 4
M Miloš Mitrović, MD

Efficacy of Carminal in Helicobacter Pylori Gastritis

Eighty patients will be included and randomized in two groups, one group (40 patients) will be administered 30 ml of the supplement Carminal, once a day, plus therapy for HP gastitis and the control group (40 patients) will be given standard therapy for HP gastritis with placebo. Treatment will begin …

18 years of age All Phase 2

PyloPlus Urea Breath Test System Post Therapy Efficacy Confirmation Study

This is a multi-center, non-randomized, open label study. Subjects will be enrolled if they are deemed eligible given the inclusion criteria. Subjects who meet all inclusion criteria and none of the exclusion criteria will be entered into the study. Subjects will be exposed to non-radioactive 13C-Urea with citric acid, and …

18 years of age All Phase 3
Y Yizhen Liu, M.D., Ph.D.

Orelabrutinib in the Treatment of HP-positive Gastric MALT Lymphoma

Describe the efficacy and safety of Orelabrutinib in the treatment of HP-positive gastric MALT lymphoma

18 years of age All Phase 2
Z Zhenyu Zhang, Master

Fucoidan Assisted Eradication of Helicobacter Pylori

The purpose of this study is to investigate whether the eradication rate of H.pylori will be improved when adding fucoidan to the duplex scheme combination of amoxicillin and vonoprazan, and to explore the effect of fucoidan on gastrointestinal flora of patients.

18 - 70 years of age All Phase 1/2
M Mohamed G Flefel, MD

Potassium-Competitive Acid Blocker Versus Proton Pump Inhibitor as A Part of Bismuth Based Quadruple Therapy for Treatment of Helicobacter Pylori Infection

This study aims to compare the eradication rate, safety, and patient adherence between potassium-competitive acid blockers (P-CABs) and proton pump inhibitor-based bismuth quadruple therapy in patients with Helicobacter pylori infection.

18 years of age All Phase N/A

Helicobacter Pylori in Patients With Chronic Tonsillits Prepared for Tonsillectomy

Tonsillar disorders are frequent In both pediatric and adult otolaryngological practice, . Numerous disorders that damage tonsillar tissue necessitate tonsillectomy. Tonsillectomy is typically required for recurrent tonsillitis. (Mani et al., 2019). According to studies, the mucosa-associated lymphoid tissue (MALT) of the stomach and tonsillar tissue in the Waldeyer's ring are …

5 - 50 years of age All Phase N/A
T Tania Fleitas, MD, PhD

Personalised Health Recommendations to the General Population Through an Integrated AI Guided

This clinical study aims to be used to implement and validate the AIDA tool in two phases: Phase 1: Risk stratification and personalised recommendations & Model development Phase 2: Mechanistic Model (Bioresource) development & testing

18 years of age All Phase N/A
Y Yucheng Zhu, Ph.D.

Tegoprazan-Based Dual Therapy With Amoxicillin vs Tetracycline for H. Pylori Eradication

Current first-line Helicobacter pylori eradication protocols involve multidrug regimens comprising a proton pump inhibitor (PPI) or bismuth agent combined with dual antibiotics (e.g., clarithromycin, amoxicillin, quinolones, furazolidone, nitroimidazoles, or tetracycline) administered for 7-14 days. In China, the bismuth-containing quadruple therapy (BQT) remains the standard first-line treatment for H. pylori infection. …

18 - 70 years of age All Phase N/A

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