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dermatitis-atopic Clinical Trials

A listing of dermatitis-atopic medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 191 clinical trials
E Elise Nelson

Dupixent and Narrowband UVB for Atopic Dermatitis

24 weeks open-label study with dupilumab and narrowband UVB phototherapy three times weekly for 12 weeks followed by 12 weeks of dupilumab monotherapy.

18 - 100 years of age Both Phase 4

A Study to Evaluate the Efficacy, and Safety Study of Ruxolitinib Cream in Adults With Moderate Atopic Dermatitis

This study is being conducted to establish the efficacy of ruxolitinib cream in participants with moderate AD who had an inadequate response to, or are intolerant to, or contraindicated to topical corticosteroid (TCS)s and topical calcineurin inhibitor (TCI)s.

18 - 100 years of age Both Phase 3

Dupilumab De-escalation in Pediatric Atopic Dermatitis

This is a pilot investigator-blinded, randomized clinical trial to assess the feasibility of dupilumab treatment discontinuation or dose-reduction in children aged 1-17 years who have achieved sustained atopic dermatitis (AD) control on dupilumab.

1 - 17 years of age Both Phase 4

A Study of LY3872386 in Healthy Participants and Participants With Atopic Dermatitis

The main purpose of this study is to evaluate the safety and tolerability of LY3872386 in healthy participants and participants with atopic dermatitis. The safety of prednisone is also evaluated in healthy participants. Blood tests will be performed to investigate how the body processes the LY3872386 following single and multiple …

18 - 65 years of age Both Phase 1

Moisturizer Mediated Prevention of Symptoms of Atopic Dermatitis in Early Childhood

In this study, it will be investigated if symptoms of atopic dermatitis of children with high familial risk will be delayed beyond the 6th or even 12th month of life by applying the SanaCutan Basiscreme.

- 21 years of age Both Phase 3
T Tsen-Fang Tsai, MD

UVB-induced Treg Cells Exert Antigen-specific Suppression Through LAG-3

The goal of this clinical trial is to compare the immune cell population in blood of the participants with psoriasis/atopic dermatitis before and after UVB treatment. The main questions it aims to answer are: how immune cells in the PBMCs from blood of participants are affected by UVB treatment will …

20 - 100 years of age Both Phase N/A

FIH Study to Evaluate the Tolerability of PF-07832837 in Healthy Adults and Patients

The purpose of the study is to evaluate the safety, tolerability, and pharmacokinetics of escalating single and repeat doses of PF-07832837 in healthy participants and in participants with moderate to severe atopic dermatitis. An additional goal is to assess the pharmacodynamics of PF-07832837 in participants with moderate to severe AD, …

18 - 70 years of age Both Phase 1
M Mathijs R de Veer, MSc

Effect of EMD Protocol for Urge on Dermatology-specific Quality of Life

The primary objective of this open randomised controlled trial is to assess the add-on effect of EMD-U compared to CAU alone, in improving dermatology-specific quality of life in patients with atopic dermatitis or prurigo nodularis who suffer from severe scratching behaviour. The main study parameter is the difference in treatment …

18 - 100 years of age Both Phase N/A
F For more information at the NIH Clinical Center contact Office of Patient Recruitment (OPR)

Effects of Treatments on Atopic Dermatitis

Background Atopic dermatitis, or eczema, is a chronic skin disorder. Patients sometimes have infections with S. aureus bacteria. Researchers want to study how eczema treatments affect the number and the type of bacteria on the skin. Objectives To study the effect of eczema treatments on skin bacteria. Eligibility Individuals between …

2 - 50 years of age Both Phase 2
C Charles CASSIUS

Meditation in Inflammatory Dermatosis

Psoriasis and atopic dermatitis are multifactorial inflammatory dermatoses, with a very high prevalence, reaching more than 120 million patients in the world. Although the physiopathological mechanisms are not yet clearly defined, these inflammatory dermatoses involve an interaction between the immune system and the epidermal cells, severe skin inflammation and often …

18 - 100 years of age Both Phase N/A

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