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pain Clinical Trials

A listing of pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,605 clinical trials
V Vasileios Balomenos, MD, MSc, PhD(c)

Cryoneurolysis Prior to Total Knee Arthroplasty (CRYO-TKA Trial)

Approximately 20-30% of patients experience persistent pain after a Total Knee Arthroplasty (TKA). This study investigates whether percutaneous cryoneurolysis of genicular nerves can reduce pain and improve physical function when performed at least 24 hours before surgery. Participants will be randomized to receive either the cryoneurolysis procedure + TKA or …

18 years of age All Phase N/A

Auricular Acupuncture in Patients With Multiple Myeloma

In the present study, the effect of ear acupressure treatment according to the NADA protocol on the quality of life of patients with multiple myeloma (all stages) will be investigated. Furthermore, the effect of ear acupressure on anxiety and depression, pain, fatigue and sleep of the patients will be assessed.

18 - 70 years of age All Phase N/A
A Ali Bin Asim, MS-OMPT

Effect of Muscle Energy Technique on Latissimus Dorsi on Pain , Functional Disability and Range of Motion in Patients With Mechanical Low Back Pain

Mechanical low back pain (LBP) stems from spinal structures or surrounding tissues, often caused by overuse or trauma, and is prevalent globally with high recurrence rates. Key contributing factors include biomechanical, psychological, and social elements. The latissimus dorsi (LD), along with other back muscles, plays a crucial role in lumbar …

30 - 55 years of age All Phase N/A

Effectiveness of Anti-Inflammatory Drugs for Preventing Pain Versus Treating Pain During Medical Abortion From 13 to 22 Weeks at Hung Vuong Hospital

The goal of this clinical trial is to assess the effectiveness of non-steroidal anti-inflammatory drugs (NSAIDs) for prophylactic pain relief compared to on-demand pain relief during medical abortion for pregnancies between 13 and 22 weeks at Hung Vuong Hospital in Ho Chi Minh City. The main questions it aims to …

18 years of age Female Phase N/A
N Natalie Isho, MPH

Evaluate the Impact of Targeted Physical Activity on Clinically Debilitated Dialysis Patients.

This research is being done to better understand the impact of the use of a specific physical activity training program (GH Method) in dialysis/kidney disease patients.

18 years of age All Phase N/A
F Fadel Zeidan, PhD

The Effects and Mechanisms of a High CBD Cannabis Extract (BRC-002) for the Treatment of Pain and Health in Complex Regional Pain Syndrome

The aim of this trial is to determine the potential effects and mechanisms of cannabinoid-induced pain relief in complex regional pain syndrome (CRPS). Multiple psychophysical approaches will be conducted in conjunction with psychological and inflammatory marker testing to determine if and how cannabinoids produce stabilized improvement in CRPS-related pain and …

21 - 75 years of age All Phase 1
H Hira Shaukat, TDPT

Effects of Voodoo Flossing Technique in Knee Osteoarthritis Patients

Knee osteoarthritis (KOA) is a prevalent degenerative joint disease characterized by pain, stiffness, and reduced physical function, significantly impacting quality of life especially in elderly population. This study aims to evaluating the effectiveness of an emerging technique, known as 'Voodoo Flossing' on pain, range of motion and physical function in …

45 - 65 years of age All Phase N/A
R Robert E Sorge, PhD

Diet Interventions, by Race, Evaluated as Complementary Treatments for Pain

Knee osteoarthritis (OA) is the most prevalent form of arthritis and race is a risk factor for poor outcomes. Non-Hispanic Black individuals (NHB) report greater disability and pain severity compared to Non-Hispanic Whites (NHW). These differences are reinforced through social and biological mechanisms, ultimately resulting in disparities in pain experience …

40 - 75 years of age All Phase N/A
L Laurent TAVERNIER

Modality of Pain Management in Ambulatory Tonsillectomy Surgery in Adults

No SFORL recommendation for adult ambulatory tonsillectomy. This study would allow the establishment of an ambulatory management during an adult tonsillectomy. This would allow a return home from J0 for the patient and therefore would improve the comfort of the patients and reduce the cost associated with a conventional hospitalization …

18 years of age All Phase N/A
F For more information at the NIH Clinical Center contact Office of Patient Recruitment (OPR)

Effects of External Ear Stimulation on Pain Perception and Mood

Background The vagus nerve runs from the brain to many organs. Stimulating it can affect the experience of pain. The nerve can be stimulated on the surface of the left ear. Researchers want to study how this stimulation affects the perception of pain. They also want to study how mood …

18 - 50 years of age All Phase N/A

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