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pain Clinical Trials

A listing of pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,605 clinical trials
F For more information at the NIH Clinical Center contact Office of Patient Recruitment (OPR)

Resiniferatoxin for the Management of Refractory Morton s Neuroma Pain

Morton s neuroma is an irritation of the nerves that affect the feet. People with this condition may have burning or shooting pain in the balls of their feet. They may also have numbness in adjacent areas. These symptoms may become more frequent and severe over time. The pain may …

18 years of age All Phase 1
H Hannah Palanchi

Virtual Walking Intervention for Neuropathic Pain in Spinal Cord Injury

The purpose of this study is to determine if playing a virtual reality walking game can help improve neuropathic pain in adults with chronic spinal cord injury.

18 years of age All Phase N/A

RCT of Pain Perception With Fast and Slow Tenaculum Application

This project will be a randomized controlled trial (RCT) measuring pain perception with two different tenaculum placement techniques on the uterine cervix. A tenaculum is an instrument used to hold the cervix (the opening to the uterus or womb) in place. The trial will measure pain perception with a Visual …

18 years of age Female Phase N/A
T Thivya Sivarajan

rTMS and Steroid Joint Steroid Injection in Chronic Spinal Pain

Chronic spinal pain (CSP) is one of the most common chronic pain conditions globally. Steroid joint injections (SJI) are a routine treatment option for patients with CLBP that is recalcitrant to other treatments. However, SJI has been shown to have limited long-term efficacy with patients often requiring another injection within …

18 years of age All Phase N/A
J Joao M Montecchi, MD

Continuous Radiofrequency in Hip Osteoarthritis Pain: A Randomized Clinical Trial.

This will be a prospective, single-center, double-blinded, randomized study designed to compare the efficacy of the intraarticular injection of a corticosteroid and the Conventional Radiofrequency (CRF) of the anterior sensory branches to the hip in controlling pain and improving function related to hip osteoarthritis.

18 years of age All Phase N/A
B Birgül VURAL DOĞRU, Associate Professor

The Effect on Back Pain and Fatigue Level of Acupressure

This research was conducted with the aim of determining the effect of acupressure on the level of back pain and fatigue after coronary angiography.

18 - 80 years of age All Phase N/A
J John Winslow

Effect of Lumbar Manipulation on Intervertebral Motion, Pain, and Disability

Background / Purpose: There is an ongoing debate regarding the ability of physical therapists to manually sense intervertebral motion. Physical therapists use intervertebral hypomobility as a clinical indicator for spinal manipulation. Also in question is the mechanism of improvement observed after spinal manipulation. Some argue that the improvement is purely …

18 - 60 years of age All Phase N/A
J Jeppe Lange, MD, PhD

Exercise and Patient Education for Patients With Lateral Hip Pain

This prospective cohort trial will investigate a progressive exercise protocol and patient education for patients with hip abductor tendon pathology. The primary outcome is patient reported pain measured by the revised Copenhagen Hip And Groin Outcome Score (HAGOS), that will be conducted at baseline and at a 12 week follow-up.

18 - 75 years of age All Phase N/A
M Mohamed Eltorki, MBChB, MSc

Intravenous Ketorolac Vs. Morphine In Children With Acute Abdominal Pain

Appendicitis is a common condition in children 6-17 years of age, and the top reason for emergency surgery in Canada. Children with appendicitis can have very bad pain in their belly. Children often need pain medications given to them through a needle in their arm called an intravenous (IV). The …

6 - 17 years of age All Phase 3
O Omar Altirkawi

Detection of EEG-Based Biomarkers of Chronic Low Back Pain

Chronic low back pain (CLBP) is a pervasive disorder affecting up to one-fifth of adults globally and is the single greatest cause of disability worldwide. Despite the high prevalence and detrimental impact of CLBP, its treatments and mechanisms remain largely unclear. Biomarkers that predict symptom progression in CLBP support precision-based …

18 - 80 years of age All Phase N/A

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