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pain Clinical Trials

A listing of pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,605 clinical trials
M Mauro Cavarra, MSc

The Impact of Psilocybin on Pain in Fibromyalgia Patients

Rationale: Recent evidence shows that Lysergic Acid Diethylamide (LSD), even when administered in low, non-hallucinogenic doses, can produce analgesic effects and improve pain tolerance in a sample of healthy volunteers. Such results complement what was already observed with other serotonergic psychedelics such as psilocybin: survey studies and case series indicate …

18 - 65 years of age All Phase N/A

Closed-Loop Deep Brain Stimulation for Refractory Chronic Pain

Chronic pain affects 1 in 4 US adults, and many cases are resistant to almost any treatment. Deep brain stimulation (DBS) holds promise as a new option for patients suffering from treatment-resistant chronic pain, but traditional approaches target only brain regions involved in one aspect of the pain experience and …

22 - 80 years of age All Phase N/A
N Nadine ATTAL

Deep rTMS (H-coil) for Neuropathic Pain or Fibromyalgia

This study will investigate the efficacy and safety of "deep" rTMS on neuropathic pain or fibromyalgia. It will be randomized and sham controlled and will last 3 months. Patients will be randomized to receive acctive rTMS or sham rTMS and will receive repeated rTMS sessions (5 daily sessions then one …

18 - 80 years of age All Phase N/A
C Chen Chih-I

2% Lidocaine Gel in Reducing Postoperative Pain Following Haemorrhoidectomy

The study is a randomized, double-blind, controlled trial evaluating the efficacy of 2% lidocaine gel in reducing postoperative pain and analgesic consumption after haemorrhoidectomy. 222 patients undergoing Ferguson haemorrhoidectomy will be randomly assigned to receive either 2% lidocaine gel or a non-anaesthetic lubricant gel control. Pain scores using a visual …

18 - 80 years of age All Phase N/A
C Chi Wai Cheung, MBBS, MD

Peripheral Stimulation of Acupuncture Points for Low Back Pain

For decades, chronic low back pain has been one of the major health complaints in Hong Kong. Without proper management, low back pain is associated with functional disability and decreased quality of life. However, currently, there is still no "gold standard" treatment for cure of the problem.

18 years of age All Phase N/A
J Julian Gingold, MD PhD

Paracervical Block for Pain Reduction in Saline Infusion Sonograms

Inadequate pain management during gynecologic procedures is a growing women's health concern, especially as it reduces access to care for patients who may subsequently avoid further treatment. Although recent evidence has shown that local anesthesia reduces pain during certain gynecologic procedures, such as intrauterine (IUD) placements, there is still limited …

18 - 50 years of age Female Phase 4
H Hafiz Ahmad Rauf, Mbbs

"Lignocaine vs GTN Ointment for Postoperative Pain After Hemorrhoidectomy")

This study is being conducted at the Department of General Surgery, King Edward Medical University, Lahore, Pakistan. The purpose of the trial is to compare the effectiveness of topical Lignocaine ointment versus topical Glyceryl Trinitrate (GTN) ointment in reducing postoperative pain following hemorrhoidectomy. Patients undergoing hemorrhoidectomy will be randomly assigned …

18 - 60 years of age All Phase N/A

Postoperative Rotator Cuff Rehabilitation: Functional, Pain and Sleep Quality

Rotator cuff injuries are the third leasing cause of pain and disability, accounting for 16% of all musculoskeletal injuries. Following surgical intervention, patients typically undergo a 4 to 6 week immobilization period before starting physical therapy. This rehabilitation phase can last between 4 to 6 months. Despite this, there is …

50 years of age All Phase N/A
R Ryan Hellinger, BA

Duloxetine for Perioperative Pain in Hip Arthroplasty: A RCT

The primary objective of this study is to compare total narcotic intake standardized via milligram morphine equivalents between duloxetine and placebo cohorts after a total hip arthroplasty.

18 years of age All Phase 4
M Martin Gesheff

Platelet Rich Plasma Versus Corticosteroids in Hip Osteoarthritis Pain

Prospective, single-center that may go on to being multicenter, randomized trial comparing platelet rich plasma (PRP) versus corticosteroid injection for the treatment of symptoms of Hip osteoarthritis. The purpose of the study is to determine which therapy provides a greater reduction in patient reported outcome measures of pain and function.

21 - 80 years of age All Phase 4

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