Advanced Filters
noise

pain Clinical Trials

A listing of pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,605 clinical trials
E Erich Anderer

The Effect of Yoga Practice on Chronic Back Pain

Chronic low back pain is notoriously difficult to treat and is a primary contributor to lost work days and excessive health expenditures, and whose treatment has, in part, contributed to the opioid crisis. Surgery is only an option in a minority of these patients, usually confined to those with structural …

18 years of age All Phase N/A
D Donald (Hugh) L Myrick, MD BS

Effects of tDCS Combined With CBI on Postsurgical Pain

The purpose of this study is to determine whether a new medical technology can help reduce post-operative total knee or hip pain when combined with a Cognitive-Behavioral intervention (CBI). This new medical technology, is called transcranial direct current stimulation (tDCS), it uses a very small amount of electricity to temporarily …

18 - 90 years of age All Phase N/A
F For more information at the NIH Clinical Center contact Office of Patient Recruitment (OPR)

Resiniferatoxin to Treat Severe Pain Associated With Advanced Cancer

This study will examine the safety of giving the experimental drug, resiniferatoxin (RTX), to treat severe pain in patients with advanced cancer. RTX is a chemical extracted from a cactus-like plant. It is similar to capsaicin, the active ingredient in hot pepper. RTX has relieved pain and reduced the need …

18 - 99 years of age All Phase 1
N Nicole Kurata

Transcutaneous Electrical Nerve Stimulation for Post-Cesarean Pain Control

Purpose of study is to evaluate the efficacy of transcutaneous electrical nerve stimulation (TENS) for post-operative pain control after a cesarean delivery compared to placebo and no TENS.

18 years of age Female Phase N/A
D David W Sparrow, DSc

Telemedicine Intervention in Patients With Chronic Pain in PD

Pain is a very common and disabling symptom in Parkinson's disease, yet it is often untreated. This study will assess the impact of home-based physical and cognitive exercise interventions to reduce pain in this disease. This approach would offer an easily implemented and affordable way to encourage and maintain use …

40 - 89 years of age All Phase N/A
A Anastasia Keller, PhD

Transcutaneous Spinal Cord Stimulation for Chronic Low Back Pain

As a leading cause of disability worldwide, chronic low back pain (cLBP) represents a significant medical and socioeconomic problem with estimated health care spending of $87 billion/annually. The efficacy of dorsal column electrical stimulation to inhibit pain was first described over 50 years ago. Since then, several large clinical trials …

21 - 85 years of age All Phase N/A

Transcutaneous Electrical Nerve Stimulation (TENS) and Low Back Pain

Low back pain is a significant public health problem, is very prevalent, and is often characterized by the persistence of symptoms. Unfortunately, substantial improvements in people with chronic low back pain are rare, causing most people to live with the pain. People with chronic low back pain may have an …

18 - 60 years of age All Phase N/A
K Kim Dunleavy

Self-management of Low Back Pain in Horticulture Workers

The primary purpose of this hybrid comparative effectiveness and implementation study is to compare two self-management strategies to manage pain, and adjust work-related ergonomic risk in nursery and landscape workers. This cluster randomized pragmatic study will compare interventions with different degrees of support and Specific aim 1 is to determine …

18 - 65 years of age All Phase N/A
A Anne M McKenzie-Brown, MD

Low Dose Naltrexone for Pain in Patients With HIV

The increased life expectancy of Patients Living With HIV/AIDS (PLWHA) has increased the need for therapies for chronic conditions, such as chronic pain. Pain in the HIV population is often refractory and ends up being treated with chronic opioids, which are associated with adverse effects, including hyperalgesia, constipation, and risk …

18 - 65 years of age All Phase 4
B Behnam Liaghat, PhD

Exercise in Patients With Hypermobile Joints and Knee Pain

Pain associated with knee joint hypermobility is common in the adult population, but evidence on treatment is sparse. This study investigates if high-load resistance training is superior to usual care in improving activity-related pain in young patients (18-45 years) with hypermobile joints and knee pain.

18 - 45 years of age All Phase N/A

Simplify language using AI