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pain Clinical Trials

A listing of pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,805 clinical trials

Efficacy of Methylprednisolone for Pain Control After ACL Repair

Opioids are commonly used after orthopedic surgery for pain control but have been shown to increase complications, surgeries, readmissions, and risk for opioid use disorder. The purpose of this study is to investigate the impact of adding a methylprednisolone taper to the pain regimen after ACL repair surgery to determine …

13 - 50 years of age All Phase 4
A Amy Monroe

Personalized Postoperative Pain Management Following Thoracic Surgery in Adults

The proposed research is an important extension of an ongoing perioperative personalized analgesia and intravenous opioid pharmacogenetic research. This research focuses on two of the most commonly used oral opioid analgesics, oxycodone, and methadone, in adults following thoracic surgery. Major inpatient thoracic surgeries (TS) for lung disease are common and …

18 - 99 years of age All Phase N/A
Y Ying Liu

Accelerated Intermittent Theta Burst Stimulation (AiTBS)on Neuropathic Pain

The present study was designed to be the first to evaluate the efficacy of the AiTBS protocol to relieve neuropathic pain in a therapeutic setting, i.e. with repeated stimulation sessions. The investigator directly compared the analgesic efficacy of AiTBS versus conventional 10-Hz rTMS delivered to the left M1. In addition …

18 years of age All Phase N/A
A Audrey Ager

Impact of Biophoton Therapy on Chronic Severe Arthritis Pain

Study Objective The purpose of this clinical study is to evaluate if biophoton therapy, delivered by Tesla BioHealing® Biophoton Generators (Biophotonizer), can alleviate chronic severe pain. Study Design This is a randomized, double-blinded, placebo-controlled intervention clinical study to assess the effectiveness of biophoton therapy in managing chronic severe pain. Approximately …

18 - 80 years of age All Phase N/A

Impact of Muscle Degeneration in Chronic Low Back Pain

Surgical interventions for the removal of intervertebral disc fragments or to enlarge a narrow spine canal are commonly performed worldwide and are considered efficient. Concomitant low back pain is not uncommon among patients with lumbar nerve compression and neurological symptoms. When present, controversy persists in the literature regarding its ideal …

18 years of age All Phase N/A

Cognitive Functional Therapy Versus Exercises for Chronic Shoulder Pain

The objective of this clinical trial is to determine whether cognitive functional therapy is superior to therapeutic exercises for the treatment of chronic shoulder pain. The main questions it aims to answer are: Is cognitive functional therapy superior to therapeutic exercises for pain and disability in individuals with chronic shoulder …

18 - 65 years of age All Phase N/A
J Joel E Bialosky, PhD

Perspectives on Spinal Manipulative Therapy for Low Back Pain

The goal of this study is to better understand how the thoughts and beliefs of patients with low back pain and their physical therapist influence how much patients benefit from physical therapy. Participants will receive physical therapy as determined by their physical therapist including spinal manipulative therapy, exercise, and education. …

18 - 70 years of age All Phase N/A
A Alon Yechiel, M.Sc

Group Hydrotherapy Treatment for Athletes With Lower Back Pain

The effect of group hydrotherapy on chronic low back pain and function among athletes will be examined.

18 years of age All Phase N/A
D Dr. Mara Sobel, MD

Low Versus Standard Pressure Pneumoperitoneum on Shoulder Tip Pain

This proposed study is a single-center, double blind, parallel group RCT comparing the use of low (10 mm Hg) versus standard pressure (15 mm Hg) pneumoperitoneum at the time of benign gynecologic laparoscopic surgery. Patients will be randomized to the control group (standard pressure) or the intervention group (low pressure) …

18 years of age Female Phase N/A
J Julian Gingold, MD PhD

Paracervical Block for Pain Reduction in Saline Infusion Sonograms

Inadequate pain management during gynecologic procedures is a growing women's health concern, especially as it reduces access to care for patients who may subsequently avoid further treatment. Although recent evidence has shown that local anesthesia reduces pain during certain gynecologic procedures, such as intrauterine (IUD) placements, there is still limited …

18 - 50 years of age Female Phase 4

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