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pain Clinical Trials

A listing of pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,805 clinical trials

Ethanol Gel Versus Steroid in Refractory Lumbar Discogenic Pain

DISCOGEL® is on the market since 2007. About 20,000 kits were sold to date (October 2017). The device re-obtained its CE mark in 2017. A clinical evaluation was performed by bibliographic route in 2016. Clinical data on more than 600 patients treated by DISCOGEL® were analyzed. These data should be …

18 years of age All Phase N/A
H Hosam Hanna, MD

Vaginal Cuff Anesthesia and Post-Operative Pain Medication Use

The purpose of this study is to determine whether an injection of a local anesthetic (Bupivacaine with epinephrine) in the vaginal cuff prior to closure would result in less immediate postoperative pain medication and increase patient comfort/satisfaction.

18 years of age Female Phase 4
H Hafiz Ahmad Rauf, Mbbs

"Lignocaine vs GTN Ointment for Postoperative Pain After Hemorrhoidectomy")

This study is being conducted at the Department of General Surgery, King Edward Medical University, Lahore, Pakistan. The purpose of the trial is to compare the effectiveness of topical Lignocaine ointment versus topical Glyceryl Trinitrate (GTN) ointment in reducing postoperative pain following hemorrhoidectomy. Patients undergoing hemorrhoidectomy will be randomly assigned …

18 - 60 years of age All Phase N/A
F Fadi MQ Al Zoubi, PhD

Art Therapy for Adults With Chronic Low Back Pain

This project aims to assess the feasibility and preliminary efficacy of a supervised group-based art intervention for adults with chronic low back pain (CLBP).

18 - 59 years of age All Phase N/A
R Rubén Cuesta-Barriuso, PhD

Multidimensional Assessment of Chronic Pain in Severe Haemophilia A

Introduction: Haemophilia is a congenital coagulopathy characterised by haemarthrosis, mainly in the knees, ankles and elbows. Prophylactic treatment is the most effective therapeutic option for preventing or minimising these bleeds. Bispecific monoclonal antibodies have been shown to be effective in reducing bleeding in patients with haemophilia. Objectives: To investigate the …

18 years of age Male Phase N/A
M Molly E Sonenklar, MD

Virtual Reality As Adjunct Therapy for Vaso-Occlusive Pain

The goal of this randomized control clinical trial is to learn if virtual reality can be used to treat sickle cell pain in children. The main questions it aims to answer are: Does virtual reality reduce pain severity during a child's hospital stay for a vaso-occlusive pain crisis? Does virtual …

8 - 21 years of age All Phase N/A
C Chen-Fuh Lam, MD, PhD

Dinalbuphine Ester (Naldebain) for Pain Management After Cesarean Section

Inadequate postoperative pain management can lead to physical and psychological distress in patients as well as impact surgical wound healing and increase the risk of developing postoperative delirium and cardiopulmonary and thromboembolic events. Severe postoperative pain may also result in the development of chronic post-surgical pain (CPSP), which in turn …

20 years of age Female Phase 2/3
A Artur Biktimirov, MD

Study of Phantom Limb Pain Suppression Using Neuromodulation Methods

This study assesses the effectiveness of neuromodulation in alleviating pain through the stimulation of peripheral nerves. The research involves implanting electrodes for test stimulation of peripheral nerves (PNS - Peripheral Nerve Stimulation), spinal cord (SCS - Spinal Cord Stimulation), dorsal root ganglia (DRGS - Dorsal Root Ganglion Stimulation), and motor …

18 - 65 years of age All Phase N/A
M Mauro F Andreu, PhD

Contextual Factors-Enriched Standard Care on Mechanical Neck Pain

The primary purpose of this study will be to determine if a CFs-Enriched Standard Care approach is an effective treatment for mechanical neck pain in terms of reducing pain and improving function. We hypothesize that a 4-week CFs-Enriched Standard Care approach will be superior to Standard Care alone in terms …

18 years of age All Phase N/A
V Valentina Nicolardi

Quantitative Sensory Testing to Study Pain Perception in Autism

This study aims at assess sensory perception, and pain perception, in neurodivergent children and adolescent in the autism spectrum. To achieve this goal, the quantitive sensory testing (QST), a controlled and replicable protocol, will be used, to assess perception in different sensory modalities: heat sensations, mechanical detection threshold and pain …

5 - 17 years of age All Phase N/A

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