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pain Clinical Trials

A listing of pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,605 clinical trials
M Mindy Rodden, PhD, RN, CPNP-AC

Oral Acetaminophen for Post-Op Pain Management in Bariatric Surgery Patients

Adult patients with morbid obesity who have had Roux-en-Y gastric bypass (RYGB) or laparoscopic sleeve gastrectomy (LSG) surgery have impaired drug metabolism. There is a paucity of information available on how these patients metabolize acetaminophen post operatively and if drug preparation has any effect on achieving adequate pain control. The …

18 years of age All Phase 2
S Shari L Barnett

Cryoablation Effects on Acute and Chronic Pain After Thoracotomy and Thoracoscopy

The researchers will compare the common methods of post-surgical pain control, such as epidural or intercostal nerve block with a newer method called cryoablation. The research team is conducting this study to determine if cryoablation provides more effective pain control when compared to an epidural or intercostal nerve block.

18 years of age All Phase N/A
F Fadi MQ Al Zoubi, PhD

Expressive Art Therapy for Elder Adults With Chronic Low Back Pain

This research project aims to assess the feasibility of expressive art therapy for elderly adults with chronic low back pain and to evaluate the preliminary efficacy of combining art therapy with exercise intervention. Additionally, the study will investigate facilitators and barriers to participation. A mixed-methods approach will be employed, including …

60 years of age All Phase N/A
M Maria Groza

Objective Integrated Multimodal Electrophysiological Index for the Quantification of Visceral Pain

The objectives of the study are to 1) Conduct telemetric biosignals (EDA, ECG, and EMG) recording in healthy controls and IBS participants experiencing cutaneous and visceral pain; and 2) Validate the OIME index as a biomarker for quantifying pain in IBS participants and its capability to assess the treatment of …

18 - 50 years of age All Phase N/A
U Umar Aulia, AB

The Erector Spinae Plane Block For Gastrointestinal Malignancy Pain Treatment (EGIPT)

This study will target patients with gastrointestinal (GI) malignancy who present to any of 4 Penn Medicine emergency departments (EDs) with intractable abdominal pain. We will offer eligible patients an erector spinae plane block (ESPB), a regional anesthesia technique which is already offered to such patients in the ED at …

18 years of age All Phase N/A
S Samar R. Amin, lecturer

Effect of Sedation After Ultrasound-Guided Spinal Anesthesia on Back Pain

This study will evaluate whether giving sedation before spinal anesthesia, when performed with ultrasound guidance, reduces the risk of developing back pain after surgery. Spinal anesthesia is commonly used but may cause discomfort or persistent back pain in some patients. By comparing standard techniques, ultrasound guidance, and sedation, we aim …

18 - 65 years of age All Phase N/A
A Adreanne Rivera

Photobiomodulation for Lower Back Pain Post Spinal Fusion and Decompression Surgery

After spinal fusion and decompression surgery there is a possible risk of developing chronic back pain. After surgery there is typically inflammation around the operation site and this inflammation can be painful and debilitating to patients. Many possible treatment plans have been incorporated to assist the patient with recovery - …

18 - 75 years of age All Phase N/A
N Nanees E Salem, PHD

Pressure Pain Tolerance in Relation to Balance and Strength in Children

Sickle cell disease (SCD) is the most frequent life-threatening genetic hemoglobinopathy in the world and occurs due to the synthesis of abnormal hemoglobin S (HbS).Cells with sickle cell hemoglobin are stiff and sticky. When they lose their oxygen, they form into the shape of a sickle or crescent. This can …

9 - 14 years of age All Phase N/A
N Nuray ALACA

Chronic Nonspecific Neck Pain and Central Nervous System Focused Treatment Program

Neck pain is one of the most common musculoskeletal pain disorders secondary to low back pain. Pharmacological and non-medical treatments such as physiotherapy are applied in its treatment. Patients with chronic nonspecific neck pain (CNSP) can be treated with various interventions such as drug therapy, manual therapy, heat and exercise. …

18 - 65 years of age All Phase N/A
G Guangyou Duan, MD

The Effect of Coenzyme Q10 in Preventing Pain After Thoracoscopic Surgery

This study aimed to assess the effectiveness of Coenzyme Q10 in preventing both acute and chronic pain following thoracoscopic surgery, with a focus on its potential benefits in reducing the incidence and severity of pain.

18 - 75 years of age All Phase 4

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