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pain Clinical Trials

A listing of pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 2,805 clinical trials
D Dr. Kesava Reddy

Postop Pain Management in Pituitary Tumour Patients

To assess the benefit of using an additional nerve block during minimally invasive pituitary surgery, to improve pain management after surgery. The medication (Bupivacaine) or a placebo (saline) will be injected during surgery and patients will be asked about their level of pain at multiple time points in the first …

18 - 100 years of age All Phase 4
D David Ogez

Self-hypnosis Training for Chronic Pain Management

Title: Self-hypnosis training in chronic pain management: A pilot study Our primary objective concerns the effect of hypnosis intervention on change in 24h pain between T0 (pre-intervention) and T4 (3-month follow-up). The secondary objectives concern the effects of the intervention on (i) change in 24h pain between T0 and T5 …

18 years of age All Phase N/A
E Erin Clancy

Non-Narcotic Pain Control After ACL Reconstruction

This is a double-blind randomized controlled trial of standard of care therapy, either oral ketorolac (experimental group) or oral oxycodone (control group) to demonstrate efficacy in reducing the percentage of narcotic doses taken and documenting the number of patients with no exposure to any narcotics (take zero oxycodone) after undergoing …

15 - 55 years of age All Phase 3
L Leila Yazdanbakhsh

Intravesical Bupivacaine on Post-Operative Ureteroscopy Pain

Post-operative pain and lower urinary tract symptoms are common following ureteroscopy in the treatment of stone disease. The use of bupivacaine as a topical pain medication is used routinely for other urologic procedures, however, to date there are no studies that have rigorously investigated the effect of instilling bupivacaine in …

18 years of age All Phase 2
G Gabrielle Reichard

Yoga for Back Pain in Adolescent Scoliosis

The Problem: Adolescent Idiopathic Scoliosis (AIS), the pre-eminent spinal pathology affecting over 5% of children and adolescents, presents a pronounced spinal curvature exceeding 10 degrees, with prevalence amongst female adolescents at a ratio of 3:1 compared to males. A significant portion of these patients are not immediate candidates for surgical …

10 - 20 years of age All Phase N/A
C Chwan-Li (Leslie) Shen, PhD

Ginger Root Extract for Sciatic Pain Individuals

Neuropathic pain affects the quality of life of many Americans. Non-pharmacological strategies such as bioactive compounds in foods are being explored as therapeutics but can also serve as tools to better understand pain mechanisms. The previous study reported that ginger root extract supplementation palliated pain-spectrum behaviors in animals with neuropathic …

18 - 85 years of age All Phase 2
B Bodil Ehn, MD

Screening for Pregnancy Related Pelvic Girdle Pain

To perform clinical manual pain provocation tests of the pelvic joints in pain free pregnant women early in pregnancy, follow them until delivery, and compare those who develop PPGP with those who don't.

years of age Female Phase N/A
M Musa Güneş, MsC

Relationship Between Low Back Pain and Sensitization

Chronic non-specific low back pain is a common health problem that significantly affects the quality of life of individuals. Increased pain intensity leads to deficiencies in the body's sensory organization, resulting in decreased awareness. This can lead to dysfunction in body awareness, which is known as the ability of individuals …

18 - 65 years of age All Phase N/A
A Areen Khoury, DMD

Nerve Block Treatment for Chronic Jaw Pain

Study Summary: Nerve Block Treatment for Chronic Jaw Pain This study is being conducted at the TMJ (temporomandibular joint) clinic, which is part of the oral and maxillofacial surgery department. The goal is to evaluate how effective peripheral nerve blocks are in reducing long-term jaw pain in patients with chronic …

18 years of age All Phase N/A
M Mercè Matute, MD, PhD

Chronic Insomnia in Non-Cancer Pain Patients

Pain and sleep are closely linked physiological processes that support overall health and functioning. Increasing evidence shows a dynamic, bidirectional relationship: poor sleep increases pain sensitivity, while chronic pain disrupts normal sleep. Both conditions are highly prevalent and significantly impair quality of life, making them major public health concerns. Chronic …

18 years of age All Phase N/A

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