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periodontitis Clinical Trials

A listing of periodontitis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 151 clinical trials
a amal AA ali, PhD

The Effect of Low-Level Laser Therapy as an Adjunct to Non-surgical Therapy in Different Age Groups

the summary is to evaluate The Effect of Low-Level Laser Therapy as an Adjunct to Non-surgical Therapy on Inducible Nitrous Oxide Synthase Salivary Levels in Different Age Groups of Chronic Periodontitis Patients

60 - 90 years of age Both Phase N/A
R Rehab Khalil

Effects of Platelet-rich Fibrin and Vitamin Dꝫ Injections on the Periodontal Health

The study aims to evaluate the effect of using PRF and vitamin Dꝫ injections on periodontal health and parameters and compare them when used to facilitate orthodontic treatment.

18 - 40 years of age Both Phase N/A
M May Abuzoor, phD

Investigate"Clinically" the Effectiveness of Boswellia Based Intracanal Medication Compared to Calcium Hydroxide Ca(OH)2 and Ledermix on the Levels of Bacteria and Inflammatory Cytokines in Root Canals and Periradicular Tissues of Teeth With Apical Periodontitis

The objective of this study is to investigate "clinically" the effectiveness of Boswellia based intracanal medication compared to the commonly used intracanal medicaments (calcium hydroxide Ca(OH)2 and Ledermix) on the levels of bacteria and inflammatory cytokines in root canals and periradicular tissues of teeth with apical periodontitis.

20 - 60 years of age Both Phase 2/3
A Alaa Ali, Ph.D.

Non - Incised Papilla Versus Single Flap Technique In The Reconstruction Of Intrabony Defect

The present study will aim to assess the effectiveness of the non-Incised Papilla surgical approach NIPSA used for the surgical debridement of deep intraosseous defects compared to the single-flap approach SFA. Primary outcome: interproximal clinical attachment level gain Secondary outcomes: residual probing pocket depth (PPD), pocket depth (PD) reduction, recession …

18 - 100 years of age Both Phase N/A

Evaluation of Autogenous Demineralized Dentin Graft Vs Autogenous Bone Graft in Management of Intrabony Defects

The main goal is to evaluate and compare the clinical and radiographic efficacy of autogenous demineralized dentin as bone graft substitute versus autogenous bone graft when performed with modified minimally invasive surgical technique (M-MIST) in the treatment of periodontal intrabony defects. The main question is: In periodontitis patients with intrabony …

18 - 50 years of age Both Phase 4
C Cristina Garcia Godoy, DDS

Rh-PDGF vs EMD for Treatment of Intra-bony Defects

Treatment of intra-bony defects is challenging and requires extensive knowledge of the etiology, anatomy, occlusion, and available biomaterials that can be used to treat this kind of defects. Patients who received scaling and root planing at the college of dental medicine due to periodontal disease, will be screened for inclusion. …

18 - 100 years of age Both Phase 1/2
G Gregg Gilbert, DDS

Shaping the Indications for Periodontal Adjunctive Antibiotics in Dental Practice

Periodontitis is a bacterial inflammatory disease and antibiotic use is being empirically used as part of its treatment. However, a clinical practice guideline on periodontal treatment adjuncts published in 2015 identified weak evidence on the use of systemic antibiotics and large heterogeneity across small scale studies, suggesting that larger pragmatic …

40 - 100 years of age Both Phase 3
F Fernando Mota de Almeida, PhD

One vs Two Visits Root Canal Treatments in Infected Teeth

The primary aim of the study is to compare the outcome of one vs two visits endodontics (root canal treatments) performed in general dental practice of infected (necrotic) teeth, one and four years after treatment. Secondary aims are to compare the root filling quality and the frequency of complications for …

18 - 100 years of age Both Phase N/A
H Heidi Fischer, Midwife

Oral Health and Adverse Pregnancy Complications

Pregnant women are susceptible to develop periodontitis, but these oral health changes related to pregnancy are often neglected. Periodontitis is accompanied by a low-grade systemic inflammation and can be harmful to the general health of the woman, contribute to pre-term birth and adversely influence the future health and metabolism of …

16 - 48 years of age Female Phase N/A
R Rinat Ezra, PhD

Different Surgical Modalities in the Treatment of Periodontitis

The purpose of the present study is to determine: 1) the efficacy of 2 periodontal surgical procedures, the conservative simplified papilla preservation technique and the more resective open flap debridement with osseous recontouring, in the treatment of chronic periodontitis in terms of clinical, radiographic, microbiological, immunological and PROMs, comparing them …

30 - 100 years of age Both Phase N/A

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