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periodontitis Clinical Trials

A listing of periodontitis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 113 clinical trials

Er:YAG Laser and Air Polishing Application in Periodontal Treatment

Periodontitis (gum disease) is an infection of the gums that can lead to tooth loss. In recent years, many types of dental lasers or other devices have been used for the non-surgical treatment of periodontal diseases. However, it remains unclear whether the combined application of laser and air polishing is …

35 - 65 years of age All Phase N/A

Application of CIELab Spectrophotometry to Analyze Gingival Color: a New Perspective for Evaluating the Effectiveness of Periodontal Basic Treatment

Objective: This study aims to explore the correlation between gingival color and clinical indicators and inflammatory factors in patients with periodontitis. Method: This study aims to include 30 periodontitis patients who visited the Periodontology Department of the Second Affiliated Hospital of Zhejiang University School of Medicine from October 2024 to …

18 - 65 years of age All Phase N/A
O Osman Babayiğit

Changes in Periodontal Pocket Depth After Periodontal Treatment

This study is a prospective, observational clinical research conducted at the Department of Periodontology, Faculty of Dentistry, Necmettin Erbakan University. The study aims to evaluate periodontal records routinely obtained before treatment and throughout the treatment process from individuals who visited the clinic and were planned for non-surgical periodontal treatment. Within …

18 - 65 years of age All Phase N/A
H Hatice Yemenoglu

Anti-inflammatory Nutrition on the Outcomes of Non-surgical Periodontal Therapy

This study aimed to determine the effect of anti-inflammatory nutrition on non-surgical periodontal treatment in individuals with periodontitis by evaluating gingival crevicular fluid (GCF) and serum biomarkers and clinical periodontal parameters. A total of 100 volunteers identified as having a pro-inflammatory diet (Q3 and Q4) will be included in the …

20 - 65 years of age All Phase N/A

Effectiveness of Adjunctive Therapy of Emdogain®FL in Non-surgical Periodontal Treatment

The goal of this clinical trial is to assess the safety and effectiveness of adjunctive Emdogain® therapy in non-surgical periodontal treatment for patients with stage 3 and 4 periodontitis. The main questions it aims to answer are: Will adjunctive treatment with Emdogain® result in a greater reduction in Bleeding on …

18 years of age All Phase N/A
A Ana Castro, Professor

Biologicals in Management of Intra-Bony Defects

The aim is of this study is to evaluate and compare the effects (clinical and radiological) of different biomaterials on the repair of bone defects around the teeth. When participating in this study, persons will be scheduled for local surgical intervention of the gums. Under local anaesthesia, the gums will …

18 years of age All Phase N/A
T Tolga Tozum, DDS PhD

Utilization of a Videoscope in Periodontal Regeneration

Clinical and preclinical studies confirm that regeneration of supporting tissues of teeth lost due to periodontal disease can be achieved using the principles of minimally invasive surgery (MIS). Although this therapeutic approach is well established in clinical settings and can rescue teeth with poor or questionable prognosis, MIS approaches often …

18 - 70 years of age All Phase N/A
N Nabeel Ayappali Kalluvalappil, MDS

Study on Treatment Results and Bone Changes After Replanting Severely Affected Teeth - A Before-and-After Study.

This research aims to evaluate the effectiveness of intentional replantation (IR) as a treatment for single-rooted teeth diagnosed as hopeless due to true periodontic lesions. The study will assess changes in alveolar bone and periodontal tissues, symptom resolution, and patient-reported outcomes (satisfaction and quality of life) following the procedure. Cone …

18 - 70 years of age All Phase N/A
M Mikko Kylmänen, Master of Health Care

Regular Use of aPDT in the Management and Prevention of Periodontitis Symptoms in Diabetic Patients

This is an investigator-initiated clinical study to establish easy referral and access for diabetic patients from primary health care to oral health care facilities for preventive oral care, periodontal assessment, and treatment, and to investigate the impact of regular home use of aPDT medical device on plaque control and gingival …

18 years of age All Phase N/A
R RAJINDER KR SHARMA, MDS

Impact of Subgingival Instrumentation on Psychological Distress and Mental Health Status in Bruxers With Periodontitis

Bruxism is a non-functional repetitive jaw-muscle activity characterized by grinding or clenching the teeth. Bruxism, characterized by the involuntary grinding or clenching of teeth, is a prevalent parafunctional habit affecting individuals of all ages. Stress, anxiety, and depression are the psychological factors most commonly associated with the presence of bruxism.

30 - 50 years of age All Phase N/A

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