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brain-injury Clinical Trials

A listing of brain-injury medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 368 clinical trials
M Meghan Marotz, MS

Non-invasive Nerve Stimulation for PTSD and Sleep

In this study, our objective is to determine the effect of two different nerve stimulation types in changing sleep architecture.

18 - 55 years of age All Phase N/A
S Stefanie Howell, PhD

Traumatic Brain Injury and Stroke Long Term Outcome

Investigators will determine the long-lasting effects of post-acute rehabilitation after traumatic brain injury and stroke. Investigators will also evaluate if the beneficial effects of rehabilitation continue after discharge from a rehabilitative program.

18 years of age All Phase N/A
N Natalie Saba, BSc.

Cannabidiol as a Treatment for PTSD and PTSD Comorbid With TBI

This will be a randomized placebo controlled study to test the efficacy of cannabidiol (CBD) as a treatment for symptoms of post-traumatic stress disorder (PTSD). Subjects, 120 in total, will be males and females with PTSD, half of which will have comorbid mild traumatic brain injury (TBI). There will be …

18 - 70 years of age All Phase 2

Non-Trauma Intervention to Treat PTSD for Veterans and Service Members Suffering From a TBI

The investigators want to test a treatment for posttraumatic stress disorder (PTSD) especially designed for military veterans and service members with mild or moderate traumatic brain injuries (TBI) and PTSD. The treatment will include individual psychotherapy sessions to manage PTSD.

18 years of age All Phase N/A
I Isabelle M Taylor, MA

Rapid Treatment of PTSD With Accelerated Non-Invasive Brain Stimulation

This study will test the clinical efficacy of an accelerated TMS (accel-TMS) protocol that rapidly addresses PTSD symptoms with 1 week (25 sessions over 5 days) of condensed treatment.

18 - 65 years of age All Phase N/A
E Eric B Elbogen, PhD

Cognitive Rehabilitation for Treatment of Anger in Veterans With TBI and PTSD

This randomized clinical trial will enroll 100 Veteran-family/friend dyads to test the efficacy of CALM in treating anger in TBI and PTSD. The investigators hypothesize that compared to an active control group, Veterans randomized to the CALM group will demonstrate: Significantly larger decreases in anger dysregulation, impulsivity, and executive dysfunction. …

18 years of age All Phase N/A
S Samuel Meyer, MSc

Dizziness Due to Visual Stimuli in Patients With Concussion and Other Causes of Dizziness: Examination of Balance Behaviour

This research project aims to measure how balance is affected by special visual stimulation. Dizziness caused by complex moving visual patterns, known as optokinetic stimulation, is usually called visually induced dizziness (VID). The study includes patients with persistent symptoms after a concussion and those with non-traumatic dizziness. Healthy participants serve …

18 - 60 years of age All Phase N/A
J Jemy Delikat, OTR MA

Vestibular Rehabilitation App for Adults With Dizziness Related to mTBI

The goal of this clinical trial is to compare outcomes for standard vestibular rehabilitation home program to a digital vestibular rehabilitation home program in adults with dizziness related to mild traumatic brain injury (mTBI). The main question is whether participants who use the digital format of vestibular rehabilitation improve to …

18 years of age All Phase N/A
N Nicole Meredyth, MD

FFP In Traumatic BRAin INjury (FIT-BRAIN) Trial

The goal of this clinical trial is to learn about treatment with fresh frozen plasma (FFP) in individuals with moderate to severe traumatic brain injury. The two main question\[s\]it aims to answer are: Is the FFP treatment safe? Does the FFP treatment impact the 24-hour, 3-month and 6-month outcomes, intensive-care …

18 - 65 years of age All Phase 2/3

The Utility of Thromboelastography in Traumatic Brain Injury

Hemocoagulation disorder is recognized to have crucial effects on hemorrhagic or ischemic diseases. Coagulation-related damages secondary to traumatic brain injury are common and severe secondary insults of head trauma and often leads to a poor prognosis. In this study, we sought to assess if posttraumatic hemocoagulation disorders determined using thromboelastography …

18 - 80 years of age All Phase N/A

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