Advanced Filters
noise

brain-injury Clinical Trials

A listing of brain-injury medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 368 clinical trials

Risk Stratification in Children With Concussion

This project will measure concussion symptoms, biological markers, and academic and social factors across the first year postconcussion to develop a model that enables early identification of and symptom management for children at higher risk for persistent postconcussive symptoms. Findings will provide novel insights into the longer-term effects of concussion …

11 - 17 years of age All Phase N/A
D Debra Demski

Pro-2-Cool Pivotal Trial II

This study is being conducted to determine the clinical safety and efficacy of Pro-2-Cool mediated head and neck cooling when applied after concussion and improved symptomatology among adolescent athletes as quantified by post-concussion symptom severity (PCSS) score.

13 - 21 years of age All Phase N/A
J Julia Finn, MPH

Examining the Efficacy of the Man Therapy Platform in Reducing Problematic Anger Among Military Service Members With and Without a TBI History

The goal of this randomized controlled trial is to determine if an interactive digital solution, Man Therapy, reduces indices of problematic anger in male military service members who screen positive for problematic anger. The man questions this study aims to answer are: Does Man Therapy reduce indices of problematic anger? …

18 years of age Male Phase N/A
T Tiana Maple

Eye Recovery Automation for Post Injury Dysfunction (iRAPID)

This study will test a portable virtual reality (VR) system with integrated eye tracking called Virtual Eye Rotation Vision Exercises (VERVE). The proposed VERVE platform will deliver vergence therapy in an automated manner. This research will involve 30 non-traumatic brain injury (TBI) binocularly normal (BNC) Veterans and 50 post-traumatic convergence …

18 - 40 years of age All Phase N/A
A Ananya Tripathi, MS

Efficacy of Xeomin for Migraines in Patients With Traumatic Brain Injuries vs. Anomalous Health Incidents

This cohort study aims to compare the efficacy of Xeomin injections for migraine management in patients with a history of Traumatic Brain Injury (TBI) versus those with a history of Anomalous Health Incidents (AHI). The study will be conducted at the National Intrepid Center of Excellence (NICOE) in Bethesda, MD. …

18 years of age All Phase N/A
J Jody Roberts

Carbon Dioxide Administration and Brain Waste Clearance

The current study tests whether different exposures to carbon dioxide (CO2) can safely result in the increased movement of proteins from the brain into the blood. The investigators believe that this would be a proxy for the brain clearing waste products more effectively. The current study will use a counter-balanced …

18 - 82 years of age All Phase N/A
O Omar Soliman

Tranexamic Acid in Traumatic Brain Injury

In this study, our aim is to investigate the role of tranexamic acid for modulating the inflammation in patients with traumatic brain injury (TBI).

18 - 65 years of age All Phase 3
I Ishita Basu

Early Neuromodulation in Traumatic Brain Injury

The two goals of the proposed study are: (1) To determine how brain activity changes with cognitive recovery over time from acute to chronic phases of traumatic brain injury (TBI). (2) To determine how the time of anodal transcranial electrical stimulation (A-tES) administration affects cognitive performance and brain activity in …

18 - 80 years of age All Phase N/A
K Kristi E Pruiksma, PhD

Behavioral Insomnia Treatment in Mild Traumatic Brain Injury

This is a single site, two-armed random controlled trials (RCT) comparing six sessions of Cognitive Behavioral Therapy for Insomnia (CBT-I) with four sessions of Brief Behavioral Therapy for Insomnia (BBT-I) in service members with comorbid insomnia and prolonged postconcussive symptoms present for at least 3 months after Mild Traumatic Brain …

18 - 45 years of age All Phase N/A
S Sarah Enock

Clinical Trial Comparing the Efficacy of Two Teletherapy Programs at Improving Psychological Health in People With Brain Injury

The purpose of the study is to test two different training programs to find out which is better at helping people with a concussion or mild TBI (mTBI) improve their emotional health and well-being. Study participation is completely remote and will last approximately 8 months total, involving 4 assessment visits …

18 years of age All Phase N/A

Simplify language using AI