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brain-injury Clinical Trials

A listing of brain-injury medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Found 375 clinical trials

Comparing Concussion Education Types

The purpose of this study is to determine if there are differences in knowledge, self-efficacy, and empathy surrounding concussions, as well as intent to report a concussion, after viewing concussion education (CrashCourse and Brain Fly-Through) in 2D versus in 3D. In this randomized study, all participants will receive two types …

18 years of age All Phase N/A
K Keith Mcgregor, PhD

Brain Research Assessing Impacts of Neurophysiological Processing Speed Training in Veterans

Older veterans with a history of mild brain trauma exhibit early cognitive challenges, especially in driving-related tasks. This is attributed to alterations in the brain's excitatory/inhibitory (E/I) balance. This pilot project investigates this phenomenon by leveraging electroencephalography (EEG) to measure parietal lobe alpha rhythms during visual attention tasks. The hypothesis …

50 - 85 years of age All Phase N/A
S Sanjay Mediwala, MD

Growth Hormone Replacement Therapy in Veterans With Mild Traumatic Brain Injury (mTBI) and Adult Growth Hormone Deficiency (AGHD)

The purpose of this study is to determine whether growth hormone replacement therapy (GHRT) is effective versus placebo in the improvement of Quality of Life in patients with adult growth hormone deficiency (AGHD) and mild traumatic brain injury (mTBI).

21 - 55 years of age All Phase 3

Objectively Diagnose and Monitor Treatment of Light Sensitivity

The purpose of this project is to provide a new framework for diagnosing and monitoring treatment of light sensitivity and headache by objective measurement of facial features, pupil responses, retinal electrical responses and autonomic nerve responses to light.

18 - 80 years of age All Phase N/A
J Jonathan E Elliott, PhD

Improving Sleep in Veterans With the Polytrauma Clinical Triad

The "polytrauma clinical triad" (PCT), a highly disabling constellation of factors, is defined by the coexistence of traumatic brain injury, post-traumatic stress disorder, and chronic pain. Veterans with the PCT are medically complex, often refractory to conventional therapies, and suffer from additional related chronic sequela. Notably, sleep disturbances and cognitive …

18 - 89 years of age All Phase N/A
S Sarah Jackson, PhD

Development Of a Virtual Stress Inoculation Training (SIT) Platform and Mobile Health App

The purpose of this study is to demonstrate the feasibility and utility of SIT delivered asynchronously (self-paced) via fully virtual platform with and without the aid of a mobile health application and to determine initial change over baseline in terms of reduction in PTSD symptoms and improvement in resiliency in …

18 - 79 years of age All Phase N/A
R Raeghan Mueller

Cannabinoids and Traumatic Brain Injury: A Randomized, Placebo Controlled Trial

This is a double-blind, placebo-controlled, parallel group study designed to assess the tolerability and efficacy of fsCBD and bsCBD, compared to a placebo control, to improve cognition and traumatic brain injury-related symptoms. If eligible for the study, subjects will be randomized to receive one of the conditions for 12 weeks.

18 - 60 years of age All Phase 2
S Sandy Lwi, PhD

Brain Health & Wellness Classes for Veterans With Traumatic Brain Injury

This study is testing the usefulness of two types of Brain Health & Wellness classes for Veterans with a history of concussion to improve mental health.

18 - 75 years of age All Phase N/A
K KIm Walsh, OT

Multimodal, Enriched Environment for Rehabilitation in Chronic Traumatic Brain Injury

The goal of this study is to learn if a enhanced environment (Metro Café) with multi model approach (an approach that combines several therapies) in chronic traumatic brain injury improves outcomes of recovery better than traditional therapy. The main questions it aims to answer are: Determine the amount of therapy …

18 years of age All Phase N/A
A Ann Guernon, MS, CCC-SLP, CCRC

Neuromodulation and Neurorehabilitation for mTBI Plus PTSD

This study will determine (i) the magnitude of immediate and sustained effects of a current clinical standard interactive computer attention processing training (APT) when combined with intermittent theta burst stimulation (iTBS), a type of repetitive transcranial magnetic stimulation and (ii) determine how APT + iTBS changes the neurocognitive system of …

18 - 60 years of age All Phase N/A

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